Meta-Analysis of Randomized and Observational Studies Off-Pump Coronary Artery Surgery for Reducing Mortality and Morbidity:

doi:10.1016/j.jacc.2005.05.064 J. Am. Coll. Cardiol. published online Aug 24, 2005; A. Borger, Keyvan Karkouti, and Robert J. Cusimano Duminda N. Wijeysundera, W. Scott Beattie, George Djaiani, Vivek Rao, MichaelMeta-Analysis of Randomized and Observational Studies Off-Pump Coronary Artery Surgery for Reducing Mortality and Morbidity:This information is current as of May 14, 2011 http://content.onlinejacc.org/cgi/content/full/j.jacc.2005.05.064v1 located on the World Wide Web at: The online version of this article, along with updated information and services, isDownloaded from content.onlinejacc.org

[1]  J. Légaré,et al.  Conversion to on pump from OPCAB is associated with increased mortality: results from a randomized controlled trial. , 2005, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[2]  D. Bainbridge,et al.  Does Off-pump Coronary Artery Bypass Reduce Mortality, Morbidity, and Resource Utilization When Compared with Conventional Coronary Artery Bypass? A Meta-analysis of Randomized Trials , 2005, Anesthesiology.

[3]  T. Athanasiou,et al.  Does off-pump coronary artery bypass reduce the incidence of post-operative atrial fibrillation? A question revisited. , 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[4]  D. Grobbee,et al.  Meta-analysis on the effect of off-pump coronary bypass surgery. , 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[5]  Song Wan,et al.  Beating heart revascularization with or without cardiopulmonary bypass: evaluation of inflammatory response in a prospective randomized study. , 2004, The Journal of thoracic and cardiovascular surgery.

[6]  P. Falcoz,et al.  Beating versus arrested heart coronary revascularization: evaluation by cardiac troponin I release. , 2004, The Annals of thoracic surgery.

[7]  J. Pepper,et al.  Do off-pump techniques reduce the incidence of postoperative atrial fibrillation in elderly patients undergoing coronary artery bypass grafting? , 2004, The Annals of thoracic surgery.

[8]  W. Weintraub,et al.  Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial. , 2004, JAMA.

[9]  N. Doll,et al.  On-pump versus off-pump coronary artery bypass grafting: impact on postoperative renal failure requiring renal replacement therapy. , 2004, The Annals of thoracic surgery.

[10]  M. Jahangiri,et al.  S100 protein and its relation to cerebral microemboli in on-pump and off-pump coronary artery bypass surgery. , 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[11]  A. Grayson,et al.  Acute renal failure in coronary artery bypass surgery: independent effect of cardiopulmonary bypass. , 2004, The Annals of thoracic surgery.

[12]  P. Widimsky,et al.  Off-pump versus on-pump coronary surgery: final results from a prospective randomized study PRAGUE-4. , 2004, The Annals of thoracic surgery.

[13]  J. Pepper,et al.  A randomized comparison of off-pump and on-pump multivessel coronary-artery bypass surgery. , 2004, The New England journal of medicine.

[14]  J. Légaré,et al.  Coronary Bypass Surgery Performed off Pump Does Not Result in Lower In-Hospital Morbidity Than Coronary Artery Bypass Grafting Performed on Pump , 2004, Circulation.

[15]  J. Pepper,et al.  Off-pump myocardial revascularization is associated with less incidence of stroke in elderly patients. , 2004, The Annals of thoracic surgery.

[16]  G. Nasso,et al.  High risk coronary artery bypass patient: incidence, surgical strategies, and results. , 2004, The Annals of thoracic surgery.

[17]  A. Galloway,et al.  Propensity case-matched analysis of off-pump coronary artery bypass grafting in patients with atheromatous aortic disease. , 2004, The Journal of thoracic and cardiovascular surgery.

[18]  E. Buffolo,et al.  Off-pump versus on-pump myocardial revascularization in low-risk patients with one or two vessel disease: perioperative results in a multicenter randomized controlled trial. , 2004, The Annals of thoracic surgery.

[19]  M. Robson,et al.  Effects of Off-Pump Versus On-Pump Coronary Surgery on Reversible and Irreversible Myocardial Injury: A Randomized Trial Using Cardiovascular Magnetic Resonance Imaging and Biochemical Markers , 2004, Circulation.

[20]  L. Wiklund,et al.  Off‐pump CABG reduces complement activation but does not significantly affect peripheral endothelial function: a prospective randomized study , 2004, Scandinavian cardiovascular journal : SCJ.

[21]  A. Boening,et al.  Early and medium-term results after on-pump and off-pump coronary artery surgery: a propensity score analysis. , 2003, The Annals of thoracic surgery.

[22]  S. Tregear,et al.  Meta-analysis of short-term and mid-term outcomes following off-pump coronary artery bypass grafting. , 2003, The Annals of thoracic surgery.

[23]  M. Mack,et al.  Patient Selection and Current Practice Strategy for Off-pump Coronary Artery Bypass Surgery , 2003, Circulation.

[24]  J. Ahonen,et al.  Myocardial metabolism on off-pump surgery; a randomized study of 50 cases. , 2003, Scandinavian cardiovascular journal : SCJ.

[25]  M. Metra,et al.  Off-pump coronary artery bypass surgery technique for total arterial myocardial revascularization: a prospective randomized study. , 2003, The Annals of thoracic surgery.

[26]  F. Veglia,et al.  Oxygen metabolism during and after cardiac surgery: role of CPB. , 2003, The Annals of thoracic surgery.

[27]  J. Pepper,et al.  Is the use of cardiopulmonary bypass for multivessel coronary artery bypass surgery an independent predictor of operative mortality in patients with ischemic left ventricular dysfunction? , 2003, The Annals of thoracic surgery.

[28]  Alan Stein,et al.  Benefits of off-pump bypass on neurologic and clinical morbidity: a prospective randomized trial. , 2003, The Annals of thoracic surgery.

[29]  L. Bonati,et al.  Off-pump versus on-pump coronary artery bypass: meta-analysis of currently available randomized trials. , 2003, The Annals of thoracic surgery.

[30]  Laura P Coombs,et al.  The Society of Thoracic Surgeons: 30-day operative mortality and morbidity risk models. , 2003, The Annals of thoracic surgery.

[31]  D. Hett,et al.  A prospective randomized study to evaluate splanchnic hypoxia during beating-heart and conventional coronary revascularization. , 2003, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[32]  C. Maynard,et al.  Use of Off‐Pump and On‐Pump CABG Strategies in Current Clinical Practice: The Clinical Outcomes Assessment Program of the State of Washington , 2003, Journal of cardiac surgery.

[33]  G. Angelini,et al.  Off-pump coronary artery bypass surgery: the implications of the evidence. , 2003, The Journal of thoracic and cardiovascular surgery.

[34]  W. Weintraub,et al.  Off-pump coronary artery bypass grafting provides complete revascularization with reduced myocardial injury, transfusion requirements, and length of stay: a prospective randomized comparison of two hundred unselected patients undergoing off-pump versus conventional coronary artery bypass grafting. , 2003, The Journal of thoracic and cardiovascular surgery.

[35]  D. A. Wellman,et al.  An appraisal of multivariable logistic models in the pulmonary and critical care literature. , 2003, Chest.

[36]  Volkmar Falk,et al.  Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients. , 2003, The Annals of thoracic surgery.

[37]  D. Grobbee,et al.  A comparison of on-pump and off-pump coronary bypass surgery in low-risk patients. , 2003, The New England journal of medicine.

[38]  M. Caputo,et al.  Effect of off-pump coronary surgery with right ventricular assist device on organ function and inflammatory response: a randomized controlled trial. , 2002, The Annals of thoracic surgery.

[39]  M. Mack,et al.  Outcomes experience with off-pump coronary artery bypass surgery in women. , 2002, The Annals of thoracic surgery.

[40]  S Karthikeyan,et al.  Assessment of neurocognitive impairment after off-pump and on-pump techniques for coronary artery bypass graft surgery: prospective randomised controlled trial , 2002, BMJ : British Medical Journal.

[41]  N. Smedira,et al.  Does off-pump coronary surgery reduce morbidity and mortality? ☆ ☆☆ , 2002 .

[42]  L. Bonchek.  Off-pump coronary bypass: Is it for everyone? , 2002, The Journal of thoracic and cardiovascular surgery.

[43]  N. Yonan,et al.  The effect off-pump coronary artery bypass surgery on in-hospital mortality and morbidity. , 2002, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[44]  G. Grunkemeier,et al.  Propensity score analysis of stroke after off-pump coronary artery bypass grafting. , 2002, The Annals of thoracic surgery.

[45]  G. Angelini,et al.  Predictors of stroke in the modern era of coronary artery bypass grafting: a case control study. , 2002, The Annals of thoracic surgery.

[46]  S. Ohri,et al.  A prospective randomized study to evaluate the renoprotective action of beating heart coronary surgery in low risk patients. , 2002, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[47]  Raimondo Ascione,et al.  Early and midterm outcome after off-pump and on-pump surgery in Beating Heart Against Cardioplegic Arrest Studies (BHACAS 1 and 2): a pooled analysis of two randomised controlled trials , 2002, The Lancet.

[48]  H. Hirose,et al.  Side clamp used during off-pump coronary artery bypass does not increase the risk of stroke. , 2002, Medical science monitor : international medical journal of experimental and clinical research.

[49]  W. Cohn,et al.  In-hospital outcomes of off-pump versus on-pump coronary artery bypass procedures: a multicenter experience. , 2001, The Annals of thoracic surgery.

[50]  D. Grobbee,et al.  Early Outcome After Off-Pump Versus On-Pump Coronary Bypass Surgery: Results From a Randomized Study , 2001, Circulation.

[51]  M. di Mauro,et al.  Myocardial revascularization with and without cardiopulmonary bypass in multivessel disease: impact of the strategy on early outcome. , 2001, The Annals of thoracic surgery.

[52]  G. Grunwald,et al.  Off-pump coronary artery bypass is associated with improved risk-adjusted outcomes. , 2001, The Annals of thoracic surgery.

[53]  E. Covino,et al.  Surgical myocardial revascularization (CABG) in patients with pulmonary disease: beating heart versus cardiopulmonary bypass. , 2001, The Journal of cardiovascular surgery.

[54]  I. Hassinen,et al.  Myocardial preservation during coronary surgery with and without cardiopulmonary bypass. , 2001, The Annals of thoracic surgery.

[55]  J. Tamis-Holland,et al.  Atrial fibrillation after minimally invasive direct coronary artery bypass surgery. , 2000, Journal of the American College of Cardiology.

[56]  E. Trampitsch,et al.  Off-pump coronary bypass operations significantly reduce S100 release: an indicator for less cerebral damage? , 2000, The Annals of thoracic surgery.

[57]  K. Yun,et al.  Pulmonary abnormalities after coronary arterial bypass grafting operation: cardiopulmonary bypass versus mechanical stabilization. , 2000, The Annals of thoracic surgery.

[58]  V Falk,et al.  Neuromonitoring and neurocognitive outcome in off-pump versus conventional coronary bypass operation. , 2000, The Annals of thoracic surgery.

[59]  M. Galiñanes,et al.  Off-pump bypass graft operation significantly reduces oxidative stress and inflammation. , 2000, The Annals of thoracic surgery.

[60]  I. Olkin,et al.  Improving the quality of reports of meta-analyses of randomised controlled trials: the QUOROM statement , 1999, The Lancet.

[61]  V. Gulielmos,et al.  Influence of median sternotomy on the psychosomatic outcome in coronary artery single-vessel bypass grafting. , 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[62]  A. Bochenek,et al.  Cardiac troponin T release during coronary surgery using intermittent cross-clamp with fibrillation, on-pump and off-pump beating heart. , 1999, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[63]  D. Cook,et al.  Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? , 1998, The Lancet.

[64]  W. van Oeveren,et al.  Reduction of the inflammatory response in patients undergoing minimally invasive coronary artery bypass grafting. , 1998, The Annals of thoracic surgery.

[65]  G. Smith,et al.  Meta-analysis Spurious precision? Meta-analysis of observational studies , 1998, BMJ.

[66]  C. Hack,et al.  Activation of the complement system during and after cardiopulmonary bypass surgery: postsurgery activation involves C-reactive protein and is associated with postoperative arrhythmia. , 1997, Circulation.

[67]  J. Gold,et al.  Impact of embolization during coronary artery bypass grafting on outcome and length of stay. , 1997, The Annals of thoracic surgery.

[68]  O. Taşdemír,et al.  Comparison of the Early Results of Coronary Artery Bypass Grafting With and Without Extracorporeal Circulation , 1995, The Thoracic and cardiovascular surgeon.

[69]  Robert Emery,et al.  Comparison of coronary bypass surgery with and without cardiopulmonary bypass in patients with multivessel disease. , 2004, The Journal of thoracic and cardiovascular surgery.

[70]  B. Lytle,et al.  Equivalent midterm outcomes after off-pump and on-pump coronary surgery. , 2004, The Journal of thoracic and cardiovascular surgery.

[71]  E. Fosse,et al.  Clinical and Angiographic Outcome of Coronary Surgery with and without Cardiopulmonary Bypass: A Prospective Randomized Trial. , 2004, The heart surgery forum.

[72]  J. Lundahl,et al.  Activation of complement and leukocyte receptors during on- and off pump coronary artery bypass surgery. , 2004, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

[73]  M. Carrier,et al.  Randomized trial comparing off-pump to on-pump coronary artery bypass grafting in high-risk patients. , 2003, The heart surgery forum.

[74]  R. Baker,et al.  The Octopus II stabilizing system: biochemical and neuropsychological outcomes in coronary artery bypass surgery. , 2001, The heart surgery forum.

[75]  C. Yakut,et al.  Different CABG methods in patients with chronic obstructive pulmonary disease. , 2001, The Annals of thoracic surgery.

[76]  M. Czerny,et al.  Complete revascularization in coronary artery bypass grafting with and without cardiopulmonary bypass. , 2001, The Annals of thoracic surgery.