Mitochondria and free radicals in neurodegenerative diseases

Historical Overview Basic Concepts of Mitochondrial Function and Free Radical Generation Relationship of Mitochondrial Dysfunction to Excitoxicity and Apoptosis The Role of Mitochondrial Dysfunction in Animal Models of Neurodegenerative Disease Neurologic Dysfunction in Known Mitochondrial Diseases The Role of Mitochondria and Oxidative Damage in Neurodegenerative Diseases Therapeutic Approaches to Neurodegenerative Diseases Implicated by Mitochondrial Dysfunction.