DHEA for postmenopausal women: a review of the evidence.

[1]  V. Montori,et al.  A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA treatment effects on quality of life in women with adrenal insufficiency. , 2009, The Journal of clinical endocrinology and metabolism.

[2]  C. Labrie,et al.  Effect of intravaginal dehydroepiandrosterone (Prasterone) on libido and sexual dysfunction in postmenopausal women , 2009, Menopause.

[3]  C. Labrie,et al.  Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration , 2009, Menopause.

[4]  R. Wolfe,et al.  A randomized trial of oral DHEA treatment for sexual function, well-being, and menopausal symptoms in postmenopausal women with low libido. , 2009, The journal of sexual medicine.

[5]  C. Labrie,et al.  Intravaginal dehydroepiandrosterone (Prasterone), a physiological and highly efficient treatment of vaginal atrophy , 2009, Menopause.

[6]  Jenny Adams,et al.  The safety of 52 weeks of oral DHEA therapy for postmenopausal women. , 2009, Maturitas.

[7]  J. Thorp,et al.  Hypoactive sexual desire disorder in postmenopausal women: quality of life and health burden. , 2009, Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.

[8]  G. Greendale,et al.  Longitudinal changes in sexual functioning as women transition through menopause: results from the Study of Women's Health Across the Nation , 2009, Menopause.

[9]  R. Nappi,et al.  The use of estrogen therapy in women's sexual functioning (CME). , 2009, The journal of sexual medicine.

[10]  K. Nair,et al.  Effect of dehydroepiandrosterone replacement on lipoprotein profile in hypoadrenal women. , 2009, The Journal of clinical endocrinology and metabolism.

[11]  G. Braunstein,et al.  Testosterone for low libido in postmenopausal women not taking estrogen. , 2008, The New England journal of medicine.

[12]  C. Johannes,et al.  Sexual Problems and Distress in United States Women: Prevalence and Correlates , 2008, Obstetrics and gynecology.

[13]  D. V. von Mühlen,et al.  Effects of Dehydroepiandrosterone Supplementation on Cognitive Function and Quality of Life: The DHEA and Well‐Ness (DAWN) Trial , 2008, Journal of the American Geriatrics Society.

[14]  A. Genazzani,et al.  One-year therapy with 10mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu. , 2008, Maturitas.

[15]  R. Norman,et al.  Safety and Efficacy of a Testosterone Metered-Dose Transdermal Spray for Treating Decreased Sexual Satisfaction in Premenopausal Women , 2008, Annals of Internal Medicine.

[16]  K. Nair,et al.  Lack of dehydroepiandrosterone effect on a combined endurance and resistance exercise program in postmenopausal women. , 2008, The Journal of clinical endocrinology and metabolism.

[17]  F. Stanczyk,et al.  Ovarian androgen production in postmenopausal women. , 2007, The Journal of clinical endocrinology and metabolism.

[18]  S. Davis,et al.  DHEA therapy for women: effect on sexual function and wellbeing. , 2007, Human reproduction update.

[19]  R. Bérubé,et al.  Metabolism of DHEA in postmenopausal women following percutaneous administration , 2007, The Journal of Steroid Biochemistry and Molecular Biology.

[20]  D. Tindall,et al.  DHEA in elderly women and DHEA or testosterone in elderly men , 2007 .

[21]  E. Laan,et al.  Female sexual satisfaction and pharmaceutical intervention: a critical review of the drug intervention studies in female sexual dysfunction. , 2006, The journal of sexual medicine.

[22]  P. Bélanger,et al.  Androgen glucuronides, instead of testosterone, as the new markers of androgenic activity in women , 2006, The Journal of Steroid Biochemistry and Molecular Biology.

[23]  N. Watts,et al.  Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial , 2006, Menopause.

[24]  R. Rosen,et al.  Hypoactive sexual desire disorder in postmenopausal women: US results from the Women's International Study of Health and Sexuality (WISHeS) , 2006, Menopause.

[25]  J. Simard,et al.  Is dehydroepiandrosterone a hormone? , 2005, The Journal of endocrinology.

[26]  M. Seif,et al.  Testosterone for peri- and postmenopausal women. , 2005, The Cochrane database of systematic reviews.

[27]  N. Watts,et al.  Safety and Efficacy of a Testosterone Patch for the Treatment of Hypoactive Sexual Desire Disorder in Surgically Menopausal Women: A Randomized, Placebo-Controlled Trial , 2005 .

[28]  S. Davis,et al.  Androgen levels in adult females: changes with age, menopause, and oophorectomy. , 2005, The Journal of clinical endocrinology and metabolism.

[29]  K. Barnhart,et al.  Supplementation with DHEA: effect on muscle size, strength, quality of life, and lipids. , 2005, Journal of women's health.

[30]  J. Romijn,et al.  Effects of dehydroepiandrostenedione, superimposed on growth hormone substitution, on quality of life and insulin-like growth factor I in patients with secondary adrenal insufficiency: a randomized, placebo-controlled, cross-over trial. , 2005, The Journal of clinical endocrinology and metabolism.

[31]  Candace S. Brown,et al.  Testosterone Patch for Low Sexual Desire in Surgically Menopausal Women: A Randomized Trial , 2005 .

[32]  K. Nair,et al.  Effect of dehydroepiandrosterone replacement on insulin sensitivity and lipids in hypoadrenal women. , 2005, Diabetes.

[33]  D. Rubinow,et al.  Dehydroepiandrosterone monotherapy in midlife-onset major and minor depression. , 2005, Archives of general psychiatry.

[34]  D. B. Hales,et al.  Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. , 2004, Endocrine reviews.

[35]  J. Holloszy,et al.  Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial. , 2004, JAMA.

[36]  R. Auchus.  Overview of dehydroepiandrosterone biosynthesis. , 2004, Seminars in reproductive medicine.

[37]  F. Labrie.  Adrenal androgens and intracrinology. , 2004, Seminars in reproductive medicine.

[38]  L. Dennerstein,et al.  The effects of postmenopausal hormone therapies on female sexual functioning: a review of double-blind, randomized controlled trials , 2004, Menopause.

[39]  Dongmin Liu,et al.  Dehydroepiandrosterone stimulates nitric oxide release in vascular endothelial cells: evidence for a cell surface receptor , 2004, Steroids.

[40]  B. V. VON Schoultz,et al.  Serum lipids in oophorectomized women during estrogen and testosterone replacement therapy. , 2004, Maturitas.

[41]  A. Genazzani,et al.  Long-term low-dose dehydroepiandrosterone oral supplementation in early and late postmenopausal women modulates endocrine parameters and synthesis of neuroactive steroids. , 2003, Fertility and sterility.

[42]  E. Briganti,et al.  Transdermal testosterone therapy improves well-being, mood, and sexual function in premenopausal women , 2003, Menopause.

[43]  J. Simard,et al.  Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. , 2003, Endocrine reviews.

[44]  F. Labrie.  Extragonadal synthesis of sex steroids: intracrinology. , 2003, Annales d'endocrinologie.

[45]  A. von Eckardstein,et al.  Androgens and coronary artery disease. , 2003, Endocrine reviews.

[46]  E. Husebye,et al.  Replacement of dehydroepiandrosterone in adrenal failure: no benefit for subjective health status and sexuality in a 9-month, randomized, parallel group clinical trial. , 2003, The Journal of clinical endocrinology and metabolism.

[47]  Dongmin Liu,et al.  Dehydroepiandrosterone Activates Endothelial Cell Nitric-oxide Synthase by a Specific Plasma Membrane Receptor Coupled to Gαi2,3 * , 2002, The Journal of Biological Chemistry.

[48]  B. Bengtsson,et al.  Low dose dehydroepiandrosterone affects behavior in hypopituitary androgen-deficient women: a placebo-controlled trial. , 2002, The Journal of clinical endocrinology and metabolism.

[49]  H. Burger,et al.  Hormones, mood, sexuality, and the menopausal transition. , 2002, Fertility and sterility.

[50]  H. Burger,et al.  Female androgen insufficiency: the Princeton consensus statement on definition, classification, and assessment. , 2002, Fertility and sterility.

[51]  J. Heiman,et al.  Acute dehydroepiandrosterone (DHEA) effects on sexual arousal in postmenopausal women. , 2002, Journal of women's health & gender-based medicine.

[52]  M. Collison,et al.  Sex steroids and insulin resistance. , 2002, Clinical science.

[53]  H. Burger,et al.  Differing effects of low-dose estrogen–progestin therapy and pravastatin in postmenopausal hypercholesterolemic women , 2002, Climacteric : the journal of the International Menopause Society.

[54]  D. Cucinotta,et al.  Metabolic effects of dehydroepiandrosterone replacement therapy in postmenopausal women. , 2001, European journal of endocrinology.

[55]  M. Fassnacht,et al.  Dehydroepiandrosterone replacement in women with adrenal insufficiency: effects on body composition, serum leptin, bone turnover, and exercise capacity. , 2001, The Journal of clinical endocrinology and metabolism.

[56]  F. Huppert,et al.  Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial. , 2000, The Journal of clinical endocrinology and metabolism.

[57]  W. Kohrt,et al.  Effects of DHEA replacement on bone mineral density and body composition in elderly women and men , 2000, Clinical endocrinology.

[58]  Orman,et al.  Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. , 2000, The New England journal of medicine.

[59]  C. Berne,et al.  Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease , 2000, Clinical endocrinology.

[60]  E. Baulieu,et al.  Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[61]  J. Williams.  The effects of dehydroepiandrosterone on carcinogenesis, obesity, the immune system, and aging , 2000, Lipids.

[62]  S. Puccetti,et al.  Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause , 2000, Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.

[63]  K. Barnhart,et al.  The effect of deydroepiandrosterone supplementation to symptomatic perimenopausal women on serum endocrine profiles, lipid parameters, and health-related quality of life , 1999 .

[64]  M. Bidlingmaier,et al.  Dehydroepiandrosterone replacement in women with adrenal insufficiency. , 1999, The New England journal of medicine.

[65]  S. Davis,et al.  Concurrent use of simvastatin and estrogen--progestin therapy compared with each therapy alone for hypercholesterolemia in postmenopausal women. , 1999, Climacteric : the journal of the International Menopause Society.

[66]  D. Rubinow,et al.  Dehydroepiandrosterone treatment of midlife dysthymia∗ ∗ See accompanying Editorial, in this issue. , 1999, Biological Psychiatry.

[67]  S. Davis,et al.  Androgen replacement in women: a commentary. , 1999, The Journal of clinical endocrinology and metabolism.

[68]  L. Shane-McWhorter,et al.  The Role of Dehydroepiandrosterone in Diabetes Mellitus , 1999, Pharmacotherapy.

[69]  R. Haubrich,et al.  The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age‐advanced men and women , 1998, Clinical endocrinology.

[70]  N. Santoro,et al.  Postmenopausal dehydroepiandrosterone administration increases free insulin-like growth factor-I and decreases high-density lipoprotein: a six-month trial. , 1998, Fertility and sterility.

[71]  F. Labrie.  DHEA as physiological replacement therapy at menopause , 1998, Journal of endocrinological investigation.

[72]  F. Labrie,et al.  Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology. , 1997, The Journal of clinical endocrinology and metabolism.

[73]  J. Goméz,et al.  Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. , 1997, The Journal of clinical endocrinology and metabolism.

[74]  E. Barrett-Connor,et al.  The Postmenopausal Estrogen/Progestin Interventions Study: primary outcomes in adherent women. , 1997, Maturitas.

[75]  C. Kirschbaum,et al.  Effects of a two-week physiological dehydroepiandrosterone substitution on cognitive performance and well-being in healthy elderly women and men. , 1997, The Journal of clinical endocrinology and metabolism.

[76]  F. Labrie,et al.  Metabolic effects of 12-month percutaneous dehydroepiandrosterone replacement therapy in postmenopausal women , 1996 .

[77]  N. Santoro,et al.  Evidence for diminished midcycle ovarian androgen production in older reproductive aged women. , 1996, Fertility and sterility.

[78]  W. Rosner,et al.  Twenty-four-hour mean plasma testosterone concentration declines with age in normal premenopausal women. , 1995, The Journal of clinical endocrinology and metabolism.

[79]  E. Barrett-Connor,et al.  Dehydroepiandrosterone sulfate does not predict cardiovascular death in postmenopausal women. The Rancho Bernardo Study. , 1995, Circulation.

[80]  S. Yen,et al.  Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. , 1994, The Journal of clinical endocrinology and metabolism.

[81]  A. Morales.  Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age [published erratum appears in J Clin Endocrinol Metab 1995 Sep;80(9):2799] , 1994 .

[82]  W. Everaerd,et al.  Impact of climacteric on well-being. A survey based on 5213 women 39 to 60 years old. , 1993, American journal of obstetrics and gynecology.

[83]  S. Yen,et al.  90291970 The effects of oral dehydroepiandrosterone on endocrine-metabolic parameters in postmenopausal women , 1991 .

[84]  C. Labrie,et al.  Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate. , 1988, Endocrinology.

[85]  E. Barrett-Connor,et al.  A prospective study of dehydroepiandrosterone sulfate, mortality, and cardiovascular disease. , 1986, The New England journal of medicine.

[86]  Heng-hui Cheng,et al.  Dehydroepiandrosterone anti-atherogenesis effect is not via its conversion to estrogen , 2009, Acta Pharmacologica Sinica.

[87]  L. Dennerstein,et al.  Relationship between hypoactive sexual desire disorder and aging. , 2007, Fertility and sterility.

[88]  C. Coeli,et al.  Influence of methyltestosterone postmenopausal therapy on plasma lipids, inflammatory factors, glucose metabolism and visceral fat: a randomized study. , 2006, European journal of endocrinology.

[89]  S. Davis,et al.  MALE AND FEMALE SEXUAL FUNCTION AND DYSFUNCTION; ANDROLOGY Circulating Androgen Levels and Self-Reported Sexual Function in Women , 2006 .

[90]  G. Bachmann,et al.  The impact of hormones on menopausal sexuality: a literature review. , 2004, Menopause.

[91]  S. Cummings,et al.  Female sexual dysfunction in postmenopausal women: systematic review of placebo-controlled trials. , 2003, American journal of obstetrics and gynecology.

[92]  S. Davis,et al.  Androgens and female sexuality. , 2000, The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia.

[93]  B. Allolio,et al.  Dehydroepiandrosterone substitution in women. , 1999, Journal of endocrinological investigation.

[94]  J. Goméz,et al.  Journal of Clinical Endocrinology and Metabolism Printed in U.S.A. Copyright © 1997 by The Endocrine Society Effect of 12-Month Dehydroepiandrosterone Replacement Therapy on Bone, Vagina, and Endometrium in Postmenopausal Women , 2022 .