Pom1 regulates the assembly of Cdr2–Mid1 cortical nodes for robust spatial control of cytokinesis

Pom1 regulation of Cdr2 membrane association and interaction with Mid1 prevents Cdr2 assembly into stable nodes in the cell tip region, which ensures proper positioning of cytokinetic ring precursors and accurate division plane positioning in fission yeast.

[1]  M. Petronczki,et al.  Cytokinesis in animal cells. , 2015, Cold Spring Harbor perspectives in biology.

[2]  T. Pollard,et al.  Cytokinetic nodes in fission yeast arise from two distinct types of nodes that merge during interphase , 2014, The Journal of cell biology.

[3]  S. Gerber,et al.  Dueling Kinases Regulate Cell Size at Division through the SAD Kinase Cdr2 , 2014, Current Biology.

[4]  Sophie G. Martin,et al.  Distinct levels in Pom1 gradients limit Cdr2 activity and localization to time and position division , 2014, Cell cycle.

[5]  Jian-Qiu Wu,et al.  Cooperation between Rho-GEF Gef2 and its binding partner Nod1 in the regulation of fission yeast cytokinesis , 2013, Molecular biology of the cell.

[6]  K. Gould,et al.  SIN-dependent phosphoinhibition of formin multimerization controls fission yeast cytokinesis , 2013, Genes & development.

[7]  P. Nurse,et al.  Pom1 and cell size homeostasis in fission yeast , 2013, Cell cycle.

[8]  T. Toda,et al.  Fission Yeast Nod1 Is a Component of Cortical Nodes Involved in Cell Size Control and Division Site Placement , 2013, PloS one.

[9]  Sophie G. Martin,et al.  Fission yeast: in shape to divide. , 2012, Current opinion in cell biology.

[10]  J. Moseley,et al.  Blt1 and Mid1 Provide Overlapping Membrane Anchors To Position the Division Plane in Fission Yeast , 2012, Molecular and Cellular Biology.

[11]  M. Balasubramanian,et al.  Comparing contractile apparatus‐driven cytokinesis mechanisms across kingdoms , 2012, Cytoskeleton.

[12]  Erin A. White,et al.  Centralspindlin: At the heart of cytokinesis , 2012, Cytoskeleton.

[13]  T. Pollard,et al.  Characterization of structural and functional domains of the anillin-related protein Mid1p that contribute to cytokinesis in fission yeast , 2012, Molecular biology of the cell.

[14]  Sergio A. Rincon,et al.  Mid1/anillin and the spatial regulation of cytokinesis in fission yeast , 2012, Cytoskeleton.

[15]  Valerie C. Coffman,et al.  Contractile‐ring assembly in fission yeast cytokinesis: Recent advances and new perspectives , 2012, Cytoskeleton.

[16]  Jian-Qiu Wu,et al.  α-Actinin and fimbrin cooperate with myosin II to organize actomyosin bundles during contractile-ring assembly , 2012, Molecular biology of the cell.

[17]  D. Gerlich,et al.  Molecular control of animal cell cytokinesis , 2012, Nature Cell Biology.

[18]  Jian-Qiu Wu,et al.  Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis , 2012, Molecular biology of the cell.

[19]  Martin Howard,et al.  Noise reduction in the intracellular pom1p gradient by a dynamic clustering mechanism. , 2012, Developmental cell.

[20]  Jian-Qiu Wu,et al.  Model of myosin node aggregation into a contractile ring: the effect of local alignment , 2011, Journal of physics. Condensed matter : an Institute of Physics journal.

[21]  Sophie G. Martin,et al.  A Phosphorylation Cycle Shapes Gradients of the DYRK Family Kinase Pom1 at the Plasma Membrane , 2011, Cell.

[22]  K. Gould,et al.  Temporal Control of Contractile Ring Assembly by Plo1 Regulation of Myosin II Recruitment by Mid1/Anillin , 2011, Current Biology.

[23]  M. Balasubramanian,et al.  IQGAP-Related Rng2p Organizes Cortical Nodes and Ensures Position of Cell Division in Fission Yeast , 2011, Current Biology.

[24]  Valerie C. Coffman,et al.  Assembly and architecture of precursor nodes during fission yeast cytokinesis , 2011, The Journal of cell biology.

[25]  A. Laguna,et al.  DYRK family of protein kinases: evolutionary relationships, biochemical properties, and functional roles , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  V. Simanis,et al.  Dividing the Spoils of Growth and the Cell Cycle: The Fission Yeast as a Model for the Study of Cytokinesis , 2011, Cytoskeleton.

[27]  P. Janmey,et al.  Kinase Associated-1 Domains Drive MARK/PAR1 Kinases to Membrane Targets by Binding Acidic Phospholipids , 2010, Cell.

[28]  A. Paoletti,et al.  Mechanisms controlling division-plane positioning. , 2010, Seminars in cell & developmental biology.

[29]  Jian-Qiu Wu,et al.  Mechanisms of contractile-ring assembly in fission yeast and beyond. , 2010, Seminars in cell & developmental biology.

[30]  B. A. Ballif,et al.  Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. , 2010, Molecular cell.

[31]  Thomas D. Pollard,et al.  Understanding cytokinesis: lessons from fission yeast , 2010, Nature Reviews Molecular Cell Biology.

[32]  B. G. Fuller,et al.  Self-organization of intracellular gradients during mitosis , 2010, Cell Division.

[33]  K. Oegema,et al.  Analyzing the Effects of Delaying Aster Separation on Furrow Formation during Cytokinesis in the Caenorhabditis elegans Embryo , 2009, Molecular biology of the cell.

[34]  Sophie G. Martin.  Microtubule-dependent cell morphogenesis in the fission yeast. , 2009, Trends in cell biology.

[35]  Paul Nurse,et al.  A spatial gradient coordinates cell size and mitotic entry in fission yeast , 2009, Nature.

[36]  Sophie G. Martin,et al.  Polar gradients of the DYRK-family kinase Pom1 couple cell length with the cell cycle , 2009, Nature.

[37]  P. Nurse,et al.  Spatial Control of Cytokinesis by Cdr2 Kinase and Mid1/Anillin Nuclear Export , 2009, Current Biology.

[38]  Mohan K. Balasubramanian,et al.  Assembly of normal actomyosin rings in the absence of Mid1p and cortical nodes in fission yeast , 2008, The Journal of cell biology.

[39]  V. Simanis,et al.  Mid1p/anillin and the septation initiation network orchestrate contractile ring assembly for cytokinesis. , 2008, Genes & development.

[40]  M. Lemmon,et al.  Membrane recognition by phospholipid-binding domains , 2008, Nature Reviews Molecular Cell Biology.

[41]  Dimitrios Vavylonis,et al.  Assembly Mechanism of the Contractile Ring for Cytokinesis by Fission Yeast , 2008, Science.

[42]  I. Hagan,et al.  Schizosaccharomyces pombe protein phosphatase 1 in mitosis, endocytosis and a partnership with Wsh3/Tea4 to control polarised growth , 2007, Journal of Cell Science.

[43]  Sophie G. Martin,et al.  The Cell-End Factor Pom1p Inhibits Mid1p in Specification of the Cell Division Plane in Fission Yeast , 2006, Current Biology.

[44]  J. Sibarita,et al.  Pom1 kinase links division plane position to cell polarity by regulating Mid1p cortical distribution , 2006, Journal of Cell Science.

[45]  J. Vandenhaute,et al.  Three novel antibiotic marker cassettes for gene disruption and marker switching in Schizosaccharomyces pombe , 2005, Yeast.

[46]  Thomas D Pollard,et al.  Counting Cytokinesis Proteins Globally and Locally in Fission Yeast , 2005, Science.

[47]  Fred Chang,et al.  Dynamic positioning of the fission yeast cell division plane. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[48]  Nicole Bordes,et al.  C-Terminal Anchoring of mid1p to Membranes Stabilizes Cytokinetic Ring Position in Early Mitosis in Fission Yeast , 2004, Molecular and Cellular Biology.

[49]  K. Gould,et al.  The GIN4 family kinase, Cdr2p, acts independently of septins in fission yeast , 2004, Journal of Cell Science.

[50]  Thomas D Pollard,et al.  Spatial and temporal pathway for assembly and constriction of the contractile ring in fission yeast cytokinesis. , 2003, Developmental cell.

[51]  M. Balasubramanian,et al.  Sterol-rich plasma membrane domains in the fission yeast Schizosaccharomyces pombe , 2003, Journal of Cell Science.

[52]  C. Proud,et al.  Differing substrate specificities of members of the DYRK family of arginine‐directed protein kinases , 2002, FEBS letters.

[53]  P. Russell,et al.  A new inducible protein expression system in fission yeast based on the glucose-repressed inv1 promoter. , 1999, Gene.

[54]  P. Russell,et al.  The protein kinase Cdr2, related to Nim1/Cdr1 mitotic inducer, regulates the onset of mitosis in fission yeast. , 1998, Molecular biology of the cell.

[55]  K. Gould,et al.  The cdr2(+) gene encodes a regulator of G2/M progression and cytokinesis in Schizosaccharomyces pombe. , 1998, Molecular biology of the cell.

[56]  P. Philippsen,et al.  Heterologous modules for efficient and versatile PCR‐based gene targeting in Schizosaccharomyces pombe , 1998, Yeast.

[57]  J. Bähler,et al.  Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis. , 1998, Genes & development.

[58]  M. Sohrmann,et al.  The dmf1/mid1 gene is essential for correct positioning of the division septum in fission yeast. , 1996, Genes & development.

[59]  J. Boeke,et al.  Efficient targeted integration at leu1-32 and ura4-294 in Schizosaccharomyces pombe. , 1994, Genetics.

[60]  T. Blundell,et al.  Comparative protein modelling by satisfaction of spatial restraints. , 1993, Journal of molecular biology.

[61]  P. Russell,et al.  Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase , 1993, Nature.

[62]  Paul G. Young,et al.  Phosphorylation and inactivation of the mitotic inhibitor Weel by the nim1/cdr1 kinase , 1993, Nature.

[63]  T. Coleman,et al.  Negative regulation of the weel protein kinase by direct action of the nim1/cdr1 mitotic inducer , 1993, Cell.

[64]  Paul Russell,et al.  Negative regulation of mitosis by wee1 +, a gene encoding a protein kinase homolog , 1987, Cell.

[65]  P. Russell,et al.  The mitotic inducer nim1 + functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis , 1987, Cell.

[66]  Mark Bathe,et al.  Cytokinesis and the contractile ring in fission yeast: towards a systems-level understanding. , 2010, Trends in microbiology.

[67]  P. Nurse,et al.  Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. , 1996, Journal of cell science.

[68]  S. Moreno,et al.  Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. , 1991, Methods in enzymology.