Chapter 52 – Viral Responses – Hepatitis

[1]  C. Rice,et al.  Presence of functional dendritic cells in patients chronically infected with hepatitis C virus. , 2004, Blood.

[2]  C. Rice,et al.  CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection , 2004, Journal of Virology.

[3]  S. Akira,et al.  The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily , 2003, European journal of immunology.

[4]  Charles M. Rice,et al.  HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help , 2003, Science.

[5]  J. Mosnier,et al.  Phenotypic and functional characterization of intrahepatic T lymphocytes during chronic hepatitis C , 2003, Hepatology.

[6]  R. Bontrop,et al.  Chronic hepatitis C virus infection established and maintained in chimpanzees independent of dendritic cell impairment , 2003, Hepatology.

[7]  B. Walker,et al.  Ex vivo analysis of human memory CD4 T cells specific for hepatitis C virus using MHC class II tetramers. , 2003, The Journal of clinical investigation.

[8]  Antonio Bertoletti,et al.  Kinetics of the immune response during HBV and HCV infection , 2003, Hepatology.

[9]  J. Ghrayeb,et al.  Memory CD8+ T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection , 2003, The Journal of experimental medicine.

[10]  V. de Lédinghen,et al.  Evidence of viral replication in circulating dendritic cells during hepatitis C virus infection. , 2003, The Journal of infectious diseases.

[11]  Stanley M. Lemon,et al.  Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease , 2003, Science.

[12]  N. Gruener,et al.  Detection of functionally altered hepatitis C virus‐specific CD4+ T cells in acute and chronic hepatitis C , 2003, Hepatology.

[13]  C. Rice,et al.  Kinetics of CD4+ and CD8+ Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees , 2003, Journal of Virology.

[14]  D. Lewinsohn,et al.  Novel CD4+ and CD8+ T‐cell determinants within the NS3 protein in subjects with spontaneously resolved HCV infection , 2003, Hepatology.

[15]  N. Hayashi,et al.  Critical Role of MHC Class I-Related Chain A and B Expression on IFN-α-Stimulated Dendritic Cells in NK Cell Activation: Impairment in Chronic Hepatitis C Virus Infection 1 , 2003, The Journal of Immunology.

[16]  A. Lau,et al.  Dendritic cells and immune regulation in the liver , 2003, Gut.

[17]  R. Purcell,et al.  CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection , 2003, Journal of Virology.

[18]  N. Hayashi,et al.  380 IFN-γ or IL-15 restores the impaired helper T-cell polarizing ability of blood dendritic cell subsets in chronic hepatitis C , 2003 .

[19]  I. N. Crispe,et al.  Hepatic T cells and liver tolerance , 2003, Nature Reviews Immunology.

[20]  M. Massari,et al.  Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C , 2002, Journal of Virology.

[21]  B. Walker,et al.  Broad Specificity of Virus-Specific CD4+ T-Helper-Cell Responses in Resolved Hepatitis C Virus Infection , 2002, Journal of Virology.

[22]  L. Wodicka,et al.  Genomic analysis of the host response to hepatitis C virus infection , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[23]  R. Purcell,et al.  Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[24]  S. Rose-John,et al.  Reduced virus specific T helper cell induction by autologous dendritic cells in patients with chronic hepatitis B – restoration by exogenous interleukin‐12 , 2002, Clinical and experimental immunology.

[25]  S. Kamal,et al.  Peginterferon alone or with ribavirin enhances HCV-specific CD4 T-helper 1 responses in patients with chronic hepatitis C. , 2002, Gastroenterology.

[26]  J. Hoofnagle,et al.  Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection1 , 2002, The Journal of Immunology.

[27]  P. Klenerman,et al.  The dynamics of T‐lymphocyte responses during combination therapy for chronic hepatitis C virus infection , 2002, Hepatology.

[28]  D. Stolz,et al.  Reduction in the circulating pDC1/pDC2 ratio and impaired function of ex vivo-generated DC1 in chronic hepatitis B infection. , 2002, Clinical immunology.

[29]  B. Walker,et al.  Comprehensive Analysis of CD8+-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities , 2002, Journal of Virology.

[30]  J. Prieto,et al.  Abnormal Priming of CD4+ T Cells by Dendritic Cells Expressing Hepatitis C Virus Core and E1 Proteins , 2002, Journal of Virology.

[31]  A. King,et al.  Escaping High Viral Load Exhaustion , 2002, The Journal of experimental medicine.

[32]  G. Missale,et al.  Intrahepatic and circulating HLA class II–restricted, hepatitis C virus–specific T cells: Functional characterization in patients with chronic hepatitis C , 2002, Hepatology.

[33]  Yong‐jun Liu,et al.  Mouse and human dendritic cell subtypes , 2002, Nature Reviews Immunology.

[34]  S. Nuti,et al.  Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein , 2002, The Journal of experimental medicine.

[35]  B. McMahon,et al.  Chronic hepatitis B , 2001, Hepatology.

[36]  F. Chisari,et al.  Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection , 2001, The Journal of experimental medicine.

[37]  N. Kadowaki,et al.  Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens , 2001, The Journal of experimental medicine.

[38]  D. Speiser,et al.  Discrepancy between ELISPOT IFN-γ secretion and binding of A2/peptide multimers to TCR reveals interclonal dissociation of CTL effector function from TCR-peptide/MHC complexes half-life , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[39]  F. Gheyas,et al.  Depletion of circulating natural type 1 interferon-producing cells in HIV-infected AIDS patients. , 2001, Blood.

[40]  P. Klenerman,et al.  Direct ex vivo comparison of the breadth and specificity of the T cells in the liver and peripheral blood of patients with chronic HCV infection , 2001, European journal of immunology.

[41]  B. Walker,et al.  Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus , 2001, Journal of Virology.

[42]  G. Ogg,et al.  Lamivudine treatment can overcome cytotoxic T‐cell hyporesponsiveness in chronic hepatitis B: New perspectives for immune therapy , 2001, Hepatology.

[43]  A. Sette,et al.  Virus‐specific CD8+ T cells with type 1 or type 2 cytokine profile are related to different disease activity in chronic hepatitis C virus infection , 2001, European journal of immunology.

[44]  F. Zoulim,et al.  Impaired allostimulatory function of dendritic cells in chronic hepatitis C infection. , 2001, Gastroenterology.

[45]  D. Subirá,et al.  Hepatitis B virus–specific T‐cell proliferation and cytokine secretion in chronic hepatitis B e antibody–positive patients treated with ribavirin and interferon alfa , 2001 .

[46]  F. Chisari,et al.  Differential CD4+ and CD8+ T‐cell responsiveness in hepatitis C virus infection , 2001, Hepatology.

[47]  F. Chisari,et al.  Noncytolytic control of viral infections by the innate and adaptive immune response. , 2001, Annual review of immunology.

[48]  P. Klenerman,et al.  Studies of human antiviral CD8+ lymphocytes using class I peptide tetramers , 2001, Reviews in medical virology.

[49]  S. Miltenyi,et al.  BDCA-2, BDCA-3, and BDCA-4: Three Markers for Distinct Subsets of Dendritic Cells in Human Peripheral Blood , 2000, The Journal of Immunology.

[50]  T. Braciale,et al.  Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation. , 2000, The Journal of clinical investigation.

[51]  D. Vergani,et al.  Incubation phase of acute hepatitis B in man: Dynamic of cellular immune mechanisms , 2000, Hepatology.

[52]  F. Chisari,et al.  Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo , 2000, The Journal of experimental medicine.

[53]  A. B. Lyons,et al.  Analysing cell division in vivo and in vitro using flow cytometric measurement of CFSE dye dilution. , 2000, Journal of immunological methods.

[54]  M. Houghton,et al.  Liver‐Derived Hepatitis C Virus (HCV)‐Specific CD4+ T Cells Recognize Multiple HCV Epitopes and Produce Interferon Gamma , 2000, Hepatology.

[55]  M. Manns,et al.  Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C , 2000, Nature Medicine.

[56]  B. Walker,et al.  Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus , 2000, The Journal of experimental medicine.

[57]  Antonio Bertoletti,et al.  The role of virus-specific CD8(+) cells in liver damage and viral control during persistent hepatitis B virus infection. , 2000 .

[58]  J. Hoofnagle,et al.  Pathogenesis, Natural History, Treatment, and Prevention of Hepatitis C , 2000, Annals of Internal Medicine.

[59]  Roger Williams,et al.  Hepatitis C virus-specific T-cell reactivity during interferon and ribavirin treatment in chronic hepatitis C. , 2000, Gastroenterology.

[60]  N. Kadowaki,et al.  T cell activation and polarization by DC1 and DC2. , 2000, Current topics in microbiology and immunology.

[61]  C Caux,et al.  Immunobiology of dendritic cells. , 2000, Annual review of immunology.

[62]  D. Vergani,et al.  Direct ex vivo analysis of hepatitis B virus-specific CD8(+) T cells associated with the control of infection. , 1999, Gastroenterology.

[63]  D. R. Taylor,et al.  Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein. , 1999, Science.

[64]  A Sette,et al.  Presence of effector CD8+ T cells in hepatitis C virus-exposed healthy seronegative donors. , 1999, Journal of immunology.

[65]  M. Davis,et al.  Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[66]  N. Hayashi,et al.  Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. , 1999, Journal of immunology.

[67]  P Parham,et al.  Analysis of a successful immune response against hepatitis C virus. , 1999, Immunity.

[68]  B. Walker,et al.  Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection. , 1998, Journal of immunology.

[69]  B. Walker,et al.  Hepatitis C virus-specific cytolytic T lymphocyte and T helper cell responses in seronegative persons. , 1997, The Journal of infectious diseases.

[70]  Y. Yazaki,et al.  Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection , 1997, Hepatology.

[71]  C. Rice,et al.  The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C. , 1997, Journal of immunology.

[72]  C. Rice,et al.  Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients , 1996, Journal of virology.

[73]  F. Chisari,et al.  Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection. , 1996, The Journal of clinical investigation.

[74]  F. Chisari,et al.  Long-lasting memory T cell responses following self-limited acute hepatitis B. , 1996, The Journal of clinical investigation.

[75]  F. Chisari,et al.  Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection. , 1996, The Journal of clinical investigation.

[76]  T. Santantonio,et al.  Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection , 1995, The Lancet.

[77]  M. Shapiro,et al.  Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[78]  R. Steinman,et al.  Proliferating dendritic cell progenitors in human blood , 1994, The Journal of experimental medicine.

[79]  J. Hoofnagle,et al.  High levels of viral replication during acute hepatitis B infection predict progression to chronicity , 1994, Journal of medical virology.