The DNA Damage Checkpoint Response Requires Histone H2B Ubiquitination by Rad6-Bre1 and H3 Methylation by Dot1*
暂无分享,去创建一个
Paolo Plevani | P. Plevani | Federico Lazzaro | M. Muzi-Falconi | M. Giannattasio | Michele Giannattasio | Marco Muzi-Falconi | Federico Lazzaro
[1] Charles Boone,et al. A conserved RING finger protein required for histone H2B monoubiquitination and cell size control. , 2003, Molecular cell.
[2] J. Vialard,et al. The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1‐dependent hyperphosphorylation and interacts with Rad53 after DNA damage , 1998, The EMBO journal.
[3] E. Rogakou,et al. Histone H2A variants H2AX and H2AZ. , 2002, Current opinion in genetics & development.
[4] J. Haber,et al. Regulation of Saccharomyces Rad53 checkpoint kinase during adaptation from DNA damage-induced G2/M arrest. , 2001, Molecular cell.
[5] C. Gilbert,et al. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. , 2001, Molecular cell.
[6] G. Lucchini,et al. The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast. , 2000, Genes & development.
[7] W. Xiao,et al. DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae. , 2001, Mutation research.
[8] Karl Henry,et al. Rad6 plays a role in transcriptional activation through ubiquitylation of histone H2B. , 2004, Genes & development.
[9] S. Jackson,et al. Interfaces Between the Detection, Signaling, and Repair of DNA Damage , 2002, Science.
[10] P. Sung,et al. Mutation of cysteine-88 in the Saccharomyces cerevisiae RAD6 protein abolishes its ubiquitin-conjugating activity and its various biological functions. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[11] R. Rothstein,et al. Choreography of the DNA Damage Response Spatiotemporal Relationships among Checkpoint and Repair Proteins , 2004, Cell.
[12] P. Sung,et al. Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites. , 1994, Genes & development.
[13] E. Gilson,et al. Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions , 1999, Nature Genetics.
[14] Katsunori Sugimoto,et al. Association of Rad9 with Double-Strand Breaks through a Mec1-Dependent Mechanism , 2004, Molecular and Cellular Biology.
[15] P. Russell,et al. Retention but Not Recruitment of Crb2 at Double-Strand Breaks Requires Rad1 and Rad3 Complexes , 2003, Molecular and Cellular Biology.
[16] D. Stern,et al. Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint. , 2002, Molecular cell.
[17] Tom J. Petty,et al. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks , 2004, Nature.
[18] D. Gottschling,et al. The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae , 1997, Molecular and cellular biology.
[19] Michel Nussenzweig,et al. H2AX: the histone guardian of the genome. , 2004, DNA repair.
[20] A. Varshavsky,et al. The N-end rule is mediated by the UBC2(RAD6) ubiquitin-conjugating enzyme. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[21] R. T. Bree,et al. The MRN complex: coordinating and mediating the response to broken chromosomes , 2003, EMBO reports.
[22] Katsunori Sugimoto,et al. Pie1, a Protein Interacting with Mec1, Controls Cell Growth and Checkpoint Responses in Saccharomyces cerevisiae , 2001, Molecular and Cellular Biology.
[23] G. Almouzni,et al. When repair meets chromatin , 2002, EMBO reports.
[24] J. Mata,et al. Methylation of Histone H4 Lysine 20 Controls Recruitment of Crb2 to Sites of DNA Damage , 2004, Cell.
[25] M. Osley. H2B ubiquitylation: the end is in sight. , 2004, Biochimica et biophysica acta.
[26] Brian D. Strahl,et al. Gene silencing: Trans-histone regulatory pathway in chromatin , 2002, Nature.
[27] R. Bonner,et al. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks , 2003, Nature Cell Biology.
[28] J. Soulier,et al. The BRCT domain of the S. cerevisiae checkpoint protein Rad9 mediates a Rad9–Rad9 interaction after DNA damage , 1999, Current Biology.
[29] Stephen J. Elledge,et al. Cell Cycle Checkpoints: Preventing an Identity Crisis , 1996, Science.
[30] Erich A Nigg,et al. Human Asf1 and CAF‐1 interact and synergize in a repair‐coupled nucleosome assembly pathway , 2002, EMBO reports.
[31] Boris Pfander,et al. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO , 2002, Nature.
[32] D. Toczyski,et al. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. , 2001, Genes & development.
[33] G. Cagney,et al. Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II , 2003, Molecular and Cellular Biology.
[34] P. Plevani,et al. Physical and functional interactions between nucleotide excision repair and DNA damage checkpoint , 2004, The EMBO journal.
[35] D. Stern,et al. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. , 1998, Science.
[36] Philip R. Gafken,et al. Dot1p Modulates Silencing in Yeast by Methylation of the Nucleosome Core , 2002, Cell.
[37] P. Russell,et al. Histone H2A Phosphorylation Controls Crb2 Recruitment at DNA Breaks, Maintains Checkpoint Arrest, and Influences DNA Repair in Fission Yeast , 2004, Molecular and Cellular Biology.
[38] E. Rogakou,et al. DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139* , 1998, The Journal of Biological Chemistry.
[39] S. Jackson,et al. LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae , 2000, The EMBO journal.
[40] A. Emili,et al. MEC1-dependent phosphorylation of Rad9p in response to DNA damage. , 1998, Molecular cell.
[41] Yi Zhang,et al. Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. , 2003, Molecular cell.
[42] G. Almouzni,et al. Interplay between chromatin and cell cycle checkpoints in the context of ATR/ATM-dependent checkpoints. , 2004, DNA repair.
[43] G. Lucchini,et al. DNA damage checkpoint in budding yeast , 1998, The EMBO journal.
[44] Mark Johnston,et al. The Paf1 Complex Is Essential for Histone Monoubiquitination by the Rad6-Bre1 Complex, Which Signals for Histone Methylation by COMPASS and Dot1p* , 2003, Journal of Biological Chemistry.
[45] D. Toczyski,et al. A unified view of the DNA-damage checkpoint. , 2002, Current opinion in cell biology.
[46] G. Lucchini,et al. Yeast pip3/mec3 mutants fail to delay entry into S phase and to slow DNA replication in response to DNA damage, and they define a functional link between Mec3 and DNA primase , 1996, Molecular and cellular biology.
[47] M. Kastan,et al. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.
[48] M. Osley,et al. Rad6-dependent ubiquitination of histone H2B in yeast. , 2000, Science.
[49] Philipp Stelter,et al. Control of spontaneous and damage-induced mutagenesis by SUMO and ubiquitin conjugation , 2003, Nature.
[50] Kunihiro Matsumoto,et al. Recruitment of Mec1 and Ddc1 Checkpoint Proteins to Double-Strand Breaks Through Distinct Mechanisms , 2001, Science.
[51] Oscar Fernandez-Capetillo,et al. Focusing on Foci: H2AX and the Recruitment of DNA-Damage Response Factors , 2003, Cell cycle.
[52] P. Plevani,et al. Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase , 1999, The EMBO journal.
[53] P. Philippsen,et al. Additional modules for versatile and economical PCR‐based gene deletion and modification in Saccharomyces cerevisiae , 1998, Yeast.
[54] P. Sung,et al. DNA repair genes and proteins of Saccharomyces cerevisiae. , 1993, Annual review of genetics.
[55] Stephen P. Jackson,et al. A role for Saccharomyces cerevisiae histone H2A in DNA repair , 2000, Nature.