Transcription factor Runx2 is a regulator of epithelial–mesenchymal transition and invasion in thyroid carcinomas

[1]  W. Chiou,et al.  8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription. , 2011, Life sciences.

[2]  Y. M. Lee Control of RUNX3 by histone methyltransferases , 2011, Journal of cellular biochemistry.

[3]  Tomonori Kawasaki,et al.  Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells. , 2010, Human pathology.

[4]  S. Inoue,et al.  Runx2 in human breast carcinoma: its potential roles in cancer progression , 2010, Cancer science.

[5]  G. Coetzee,et al.  Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis , 2010, Molecular Cancer.

[6]  T. Stein,et al.  Runx2 in normal tissues and cancer cells: A developing story. , 2010, Blood cells, molecules & diseases.

[7]  Toyoshi Endo,et al.  Runx2 deficiency in mice causes decreased thyroglobulin expression and hypothyroidism. , 2010, Molecular endocrinology.

[8]  B. Zhou,et al.  Snail: More than EMT. , 2010, Cell adhesion & migration.

[9]  G. Stein,et al.  Runx2 Association with Progression of Prostate Cancer in Patients: Mechanisms Mediating Bone Osteolysis and Osteoblastic Metastatic Lesions , 2009, Oncogene.

[10]  S. Asa,et al.  Application of immunohistochemistry to thyroid neoplasms. , 2009, Archives of pathology & laboratory medicine.

[11]  C. Zhong,et al.  Runx2 regulates survivin expression in prostate cancer cells , 2009, Laboratory Investigation.

[12]  K. Chan,et al.  Suppression of Androgen-Independent Prostate Cancer Cell Aggressiveness by FTY720: Validating Runx2 as a Potential Antimetastatic Drug Screening Platform , 2009, Clinical Cancer Research.

[13]  Qian Chen,et al.  HDAC4 Represses Vascular Endothelial Growth Factor Expression in Chondrosarcoma by Modulating RUNX2 Activity* , 2009, The Journal of Biological Chemistry.

[14]  R. Lloyd,et al.  RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors , 2009, Endocrine.

[15]  T. Yamagata,et al.  Role of the RUNX1‐EVI1 fusion gene in leukemogenesis , 2008, Cancer science.

[16]  Ka-Kui Chan,et al.  TWIST modulates prostate cancer cell-mediated bone cell activity and is upregulated by osteogenic induction. , 2008, Carcinogenesis.

[17]  S. Asa,et al.  Epigenetic dysregulation in thyroid neoplasia. , 2008, Endocrinology and metabolism clinics of North America.

[18]  S. Asa,et al.  Enhanced B-Raf protein expression is independent of V600E mutant status in thyroid carcinomas. , 2007, Human pathology.

[19]  H. Friess,et al.  Regulation and functional role of the Runt-related transcription factor-2 in pancreatic cancer , 2007, British Journal of Cancer.

[20]  Huiling He,et al.  Gene expression and functional evidence of epithelial-to-mesenchymal transition in papillary thyroid carcinoma invasion , 2007, Proceedings of the National Academy of Sciences.

[21]  G. Stein,et al.  Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone , 2006, Cancer and Metastasis Reviews.

[22]  G. M. Nagaraja,et al.  Gene expression signatures and biomarkers of noninvasive and invasive breast cancer cells: comprehensive profiles by representational difference analysis, microarrays and proteomics , 2006, Oncogene.

[23]  S. Asa,et al.  Pathogenetic mechanisms in thyroid follicular-cell neoplasia , 2006, Nature Reviews Cancer.

[24]  T. Nakazawa,et al.  Expression of CD73 and its ecto‐5′‐nucleotidase activity are elevated in papillary thyroid carcinomas , 2006, Histopathology.

[25]  D. Papachristou,et al.  The MAPK–AP‐1/–Runx2 signalling axes are implicated in chondrosarcoma pathobiology either independently or via up‐regulation of VEGF , 2005, Histopathology.

[26]  G. Stein,et al.  The Runx2 Osteogenic Transcription Factor Regulates Matrix Metalloproteinase 9 in Bone Metastatic Cancer Cells and Controls Cell Invasion , 2005, Molecular and Cellular Biology.

[27]  T. Komori Regulation of skeletal development by the Runx family of transcription factors , 2005, Journal of cellular biochemistry.

[28]  Adalberto Costessi,et al.  Extracellular nucleotides activate Runx2 in the osteoblast-like HOBIT cell line: a possible molecular link between mechanical stress and osteoblasts' response. , 2005, Bone.

[29]  G. Stein,et al.  Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[30]  G. Xiao,et al.  Regulation of the osteoblast‐specific transcription factor, Runx2: Responsiveness to multiple signal transduction pathways , 2003, Journal of cellular biochemistry.

[31]  T. Kondo,et al.  Expression of Human Pendrin in Diseased Thyroids , 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[32]  Xin Li,et al.  Expression of thyroid transcription factor-1 (TTF-1) in human C cells and medullary thyroid carcinomas. , 2000, Human pathology.

[33]  Lucila Ohno-Machado,et al.  Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis. , 2011, Cancer research.

[34]  R. DeLellis Pathology and genetics of tumours of endocrine organs , 2004 .

[35]  Cdm Fletcher,et al.  World Health Organization Classification of Tumours , 2002 .