IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival

[1]  P. Schneider,et al.  Identification of a new subset of lymph node stromal cells involved in regulating plasma cell homeostasis , 2018, Proceedings of the National Academy of Sciences.

[2]  M. Lederman,et al.  Lymphoid tissue fibrosis is associated with impaired vaccine responses , 2018, The Journal of clinical investigation.

[3]  Chun Jimmie Ye,et al.  Single‐Cell RNA Sequencing of Lymph Node Stromal Cells Reveals Niche‐Associated Heterogeneity , 2018, Immunity.

[4]  R. Ransohoff,et al.  IL-17 induced NOTCH1 activation in oligodendrocyte progenitor cells enhances proliferation and inflammatory gene expression , 2017, Nature Communications.

[5]  S. Gaffen,et al.  IL-17 Signaling: The Yin and the Yang. , 2017, Trends in immunology.

[6]  B. Ludewig,et al.  Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands , 2017, The Journal of clinical investigation.

[7]  Shinya Abe,et al.  Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs , 2016, Nature Immunology.

[8]  Ajay S. Gulati,et al.  Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. , 2016, Immunity.

[9]  V. Kuchroo,et al.  Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions. , 2015, Immunity.

[10]  S. Ludwin,et al.  Integration of Th17- and Lymphotoxin-Derived Signals Initiates Meningeal-Resident Stromal Cell Remodeling to Propagate Neuroinflammation. , 2015, Immunity.

[11]  Erin Stevens,et al.  Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation. , 2015, Immunity.

[12]  T. Mcclanahan,et al.  Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability. , 2015, Immunity.

[13]  S. Gaffen,et al.  MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation. , 2015, Immunity.

[14]  G. Stark,et al.  A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis , 2015, The Journal of experimental medicine.

[15]  A. Berglund,et al.  Antifibrotic therapy in simian immunodeficiency virus infection preserves CD4+ T-cell populations and improves immune reconstitution with antiretroviral therapy. , 2015, The Journal of infectious diseases.

[16]  Jian Liang,et al.  MCP-induced protein 1 mediates the minocycline-induced neuroprotection against cerebral ischemia/reperfusion injury in vitro and in vivo , 2015, Journal of Neuroinflammation.

[17]  S. Turley,et al.  Fibroblastic Reticular Cells: Organization and Regulation of the T Lymphocyte Life Cycle , 2015, The Journal of Immunology.

[18]  D. Mooney,et al.  The CLEC-2–podoplanin axis controls fibroblastic reticular cell contractility and lymph node microarchitecture , 2014, Nature Immunology.

[19]  Burkhard Ludewig,et al.  B cell homeostasis and follicle confines are governed by fibroblastic reticular cells , 2014, Nature Immunology.

[20]  Sarah L. Gaffen,et al.  The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing , 2014, Nature Reviews Immunology.

[21]  M. Udey,et al.  IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms , 2014, Proceedings of the National Academy of Sciences.

[22]  W. Reith,et al.  Lymph node stromal cells acquire peptide–MHCII complexes from dendritic cells and induce antigen-specific CD4+ T cell tolerance , 2014, The Journal of experimental medicine.

[23]  Björn Usadel,et al.  Trimmomatic: a flexible trimmer for Illumina sequence data , 2014, Bioinform..

[24]  F. Tacchini-Cottier,et al.  Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes , 2013, Proceedings of the National Academy of Sciences.

[25]  G. Lenz,et al.  IκB-ζ controls the constitutive NF-κB target gene network and survival of ABC DLBCL. , 2013, Blood.

[26]  K. Druey,et al.  IL-17RA Is Essential for Optimal Localization of Follicular Th Cells in the Germinal Center Light Zone To Promote Autoantibody-Producing B Cells , 2013, The Journal of Immunology.

[27]  Thomas Rülicke,et al.  Maturation of Lymph Node Fibroblastic Reticular Cells from Myofibroblastic Precursors Is Critical for Antiviral Immunity , 2013, Immunity.

[28]  S. Akira,et al.  Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease. , 2013, Immunity.

[29]  B. Stockinger,et al.  TH17 cell plasticity in Peyer’s patches is responsible for induction of T cell-dependent IgA responses , 2013, Nature Immunology.

[30]  W. Ouyang,et al.  A role for Th17 cells in the regulation of tertiary lymphoid follicles , 2012, European journal of immunology.

[31]  David R. Kelley,et al.  Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks , 2012, Nature Protocols.

[32]  M. Lipp,et al.  Coordinated Regulation of Lymph Node Vascular–Stromal Growth First by CD11c+ Cells and Then by T and B Cells , 2011, The Journal of Immunology.

[33]  D. Plas,et al.  IKKβ and NF-κB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1. , 2011, Cancer research.

[34]  P. Nelson,et al.  Fibroblastic Reticular Cells From Lymph Nodes Attenuate T Cell Expansion by Producing Nitric Oxide , 2011, PloS one.

[35]  Limin Liu,et al.  Regulation of T Cell Priming by Lymphoid Stroma , 2011, PloS one.

[36]  Kutlu G. Elpek,et al.  Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes , 2011, Nature Immunology.

[37]  Navdeep S. Chandel,et al.  NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration , 2011, Nature Cell Biology.

[38]  N. Perkins,et al.  p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB. , 2011, Cancer research.

[39]  J. Carlis,et al.  Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections. , 2011, The Journal of clinical investigation.

[40]  D. Sturdevant,et al.  IL-17-induced NF-κB Activation via CIKS/Act1 , 2011, The Journal of Biological Chemistry.

[41]  Thomas Korn,et al.  Proinflammatory T helper type 17 cells are effective B-cell helpers , 2010, Proceedings of the National Academy of Sciences.

[42]  P. Insel,et al.  Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax , 2010, Proceedings of the National Academy of Sciences.

[43]  S. Turley,et al.  Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions , 2010, The Journal of experimental medicine.

[44]  S. Gaffen,et al.  Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa , 2009, Mucosal Immunology.

[45]  V. Kuchroo,et al.  Cutting Edge: IL-23 Receptor GFP Reporter Mice Reveal Distinct Populations of IL-17-Producing Cells1 , 2009, The Journal of Immunology.

[46]  T. Mcclanahan,et al.  The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17–producing effector T helper cells in vivo , 2009, Nature Immunology.

[47]  A. Leonardi,et al.  The Adaptor Protein CIKS/Act1 Is Essential for IL-25-Mediated Allergic Airway Inflammation1 , 2009, The Journal of Immunology.

[48]  Sergio E. Baranzini,et al.  Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets , 2008, Nature.

[49]  A. Nakagawara,et al.  Activation of AMP-activated Protein Kinase Induces p53-dependent Apoptotic Cell Death in Response to Energetic Stress* , 2008, Journal of Biological Chemistry.

[50]  Robert W. Williams,et al.  Interleukin 17–producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice , 2008, Nature Immunology.

[51]  James M. Roberts,et al.  A New Description of Cellular Quiescence , 2006, PLoS biology.

[52]  J. Cyster,et al.  Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. , 2005, Annual review of immunology.

[53]  T. Hara,et al.  Lymph Node Fibroblastic Reticular Cells Construct the Stromal Reticulum via Contact with Lymphocytes , 2004, The Journal of experimental medicine.

[54]  S. Akira,et al.  Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IκBζ , 2004, Nature.

[55]  R. Loberg,et al.  Enhanced Glycogen Synthase Kinase-3β Activity Mediates Hypoxia-induced Apoptosis of Vascular Smooth Muscle Cells and Is Prevented by Glucose Transport and Metabolism* , 2002, The Journal of Biological Chemistry.

[56]  A. Vaheri,et al.  Coordinated induction of extracellular proteolysis systems during experimental autoimmune encephalomyelitis in mice. , 2001, The American journal of pathology.