Rescue of PFOS-induced human Sertoli cell injury by overexpressing a p-FAK-Y407E phosphomimetic mutant

[1]  C. Nahmias,et al.  Regulation of end-binding protein EB1 in the control of microtubule dynamics , 2017, Cellular and Molecular Life Sciences.

[2]  B. Geiger,et al.  The Diverse Family of Arp2/3 Complexes. , 2017, Trends in cell biology.

[3]  C. Cheng,et al.  Rescue of perfluorooctanesulfonate (PFOS)-mediated Sertoli cell injury by overexpression of gap junction protein connexin 43 , 2016, Scientific Reports.

[4]  Limin Liu,et al.  Role of miR-155 in fluorooctane sulfonate-induced oxidative hepatic damage via the Nrf2-dependent pathway. , 2016, Toxicology and applied pharmacology.

[5]  C. Cheng,et al.  Coordination of Actin- and Microtubule-Based Cytoskeletons Supports Transport of Spermatids and Residual Bodies/Phagosomes During Spermatogenesis in the Rat Testis. , 2016, Endocrinology.

[6]  M. Steinmetz,et al.  Control of microtubule organization and dynamics: two ends in the limelight , 2015, Nature Reviews Molecular Cell Biology.

[7]  C. Cheng,et al.  EB1 regulates tubulin and actin cytoskeletal networks at the sertoli cell blood-testis barrier in male rats: an in vitro study. , 2015, Endocrinology.

[8]  Q. Ruan,et al.  Analysis of apoptosis induced by perfluorooctane sulfonates (PFOS) in mouse Leydig cells in vitro , 2015, Toxicology mechanisms and methods.

[9]  B. Silvestrini,et al.  Environmental toxicants perturb human Sertoli cell adhesive function via changes in F-actin organization mediated by actin regulatory proteins. , 2014, Human reproduction.

[10]  Kamin J. Johnson Testicular histopathology associated with disruption of the Sertoli cell cytoskeleton , 2014, Spermatogenesis.

[11]  R. Ge,et al.  Exposure to Perfluorooctane Sulfonate In Utero Reduces Testosterone Production in Rat Fetal Leydig Cells , 2014, PloS one.

[12]  C. Cheng,et al.  Perfluorooctanesulfonate (PFOS) perturbs male rat Sertoli cell blood-testis barrier function by affecting F-actin organization via p-FAK-Tyr(407): an in vitro study. , 2014, Endocrinology.

[13]  C. Cheng,et al.  Targeting testis-specific proteins to inhibit spermatogenesis: lesson from endocrine disrupting chemicals , 2013, Expert opinion on therapeutic targets.

[14]  Roland Weber,et al.  PFOS and PFC releases and associated pollution from a PFC production plant in Minnesota (USA) , 2013, Environmental Science and Pollution Research.

[15]  C. Cheng,et al.  Focal adhesion kinase-Tyr407 and -Tyr397 exhibit antagonistic effects on blood–testis barrier dynamics in the rat , 2012, Proceedings of the National Academy of Sciences.

[16]  Bin Wang,et al.  Emission Inventory for PFOS in China: Review of Past Methodologies and Suggestions , 2011, TheScientificWorldJournal.

[17]  G. Rabinovich,et al.  Characterization and Functionality of Proliferative Human Sertoli Cells , 2011, Cell transplantation.

[18]  C. Cheng,et al.  Regulation of spermiogenesis, spermiation and blood-testis barrier dynamics: novel insights from studies on Eps8 and Arp3. , 2011, The Biochemical journal.

[19]  C. Cheng,et al.  The β1-integrin-p-FAK-p130Cas-DOCK180-RhoA-vinculin is a novel regulatory protein complex at the apical ectoplasmic specialization in adult rat testes , 2011, Spermatogenesis.

[20]  C. Cheng,et al.  An in vitro system to study Sertoli cell blood-testis barrier dynamics. , 2011, Methods in molecular biology.

[21]  Kate Hoffman,et al.  Exposure to Polyfluoroalkyl Chemicals and Attention Deficit/Hyperactivity Disorder in U.S. Children 12–15 Years of Age , 2010, Environmental health perspectives.

[22]  C. Cheng,et al.  Restricted Arp3 expression in the testis prevents blood–testis barrier disruption during junction restructuring at spermatogenesis , 2010, Proceedings of the National Academy of Sciences.

[23]  Wenyu Bu,et al.  I-BAR domains, IRSp53 and filopodium formation. , 2010, Seminars in cell & developmental biology.

[24]  Edwin Cuppen,et al.  Small RNA expression and strain specificity in the rat , 2010, BMC Genomics.

[25]  Roberta F. White,et al.  Exposure to Polyfluoroalkyl Chemicals and Attention Deficit Hyperactivity Disorder in U.S. Children Aged 12–15 Years , 2009 .

[26]  Li Zhang,et al.  The direct effect of Focal Adhesion Kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis , 2009, BMC Cancer.

[27]  C. Cheng,et al.  Epidermal growth factor receptor pathway substrate 8 (Eps8) is a novel regulator of cell adhesion and the blood‐testis barrier integrity in the seminiferous epithelium , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[28]  C. Cheng,et al.  Focal adhesion kinase is a blood–testis barrier regulator , 2009, Proceedings of the National Academy of Sciences.

[29]  T. Scott,et al.  Developmental toxicity in white leghorn chickens following in ovo exposure to perfluorooctane sulfonate (PFOS). , 2009, Reproductive toxicology.

[30]  Hermann Fromme,et al.  Perfluorinated compounds--exposure assessment for the general population in Western countries. , 2009, International journal of hygiene and environmental health.

[31]  Kevin C Jones,et al.  A first global production, emission, and environmental inventory for perfluorooctane sulfonate. , 2009, Environmental science & technology.

[32]  C. Sander,et al.  A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing , 2007, Cell.

[33]  John W. Froehlich,et al.  Half-Life of Serum Elimination of Perfluorooctanesulfonate,Perfluorohexanesulfonate, and Perfluorooctanoate in Retired Fluorochemical Production Workers , 2007, Environmental health perspectives.

[34]  A. Koizumi,et al.  Historical trends in human serum levels of perfluorooctanoate and perfluorooctane sulfonate in Shenyang, China. , 2007, The Tohoku journal of experimental medicine.

[35]  Kellyn S. Betts,et al.  PERFLUOROALKYL ACIDS: What Is the Evidence Telling Us? , 2007, Environmental health perspectives.

[36]  Y. Lim,et al.  Focal Adhesion Kinase Is Negatively Regulated by Phosphorylation at Tyrosine 407* , 2007, Journal of Biological Chemistry.

[37]  B. Spiegelman,et al.  International Union of Pharmacology. LXI. Peroxisome Proliferator-Activated Receptors , 2006, Pharmacological Reviews.

[38]  Andrea Pfahles-Hutchens,et al.  The Applicability of Biomonitoring Data for Perfluorooctanesulfonate to the Environmental Public Health Continuum , 2006, Environmental health perspectives.

[39]  K. Helzlsouer,et al.  Historical Comparison of Perfluorooctanesulfonate, Perfluorooctanoate, and Other Fluorochemicals in Human Blood , 2005, Environmental health perspectives.

[40]  D. A. Hanson,et al.  Focal adhesion kinase: in command and control of cell motility , 2005, Nature Reviews Molecular Cell Biology.

[41]  Roger G Perkins,et al.  The Toxicology of Perfluorooctanoate , 2004, Critical reviews in toxicology.

[42]  Sutchin R. Patel,et al.  2,5-hexanedione-induced testicular injury. , 2003, Annual review of pharmacology and toxicology.

[43]  C. Cheng,et al.  Adhering junction dynamics in the testis are regulated by an interplay of beta 1-integrin and focal adhesion complex-associated proteins. , 2003, Endocrinology.

[44]  M. Nakai,et al.  Stage-specific effects of the fungicide carbendazim on Sertoli cell microtubules in rat testis. , 2002, Tissue & cell.

[45]  J. Berger,et al.  The mechanisms of action of PPARs. , 2002, Annual review of medicine.

[46]  B. Winder,et al.  The role of GTP Binding and microtubule-associated proteins in the inhibition of microtubule assembly by carbendazim. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.

[47]  C. Cheng,et al.  Testin Secreted by Sertoli Cells Is Associated with the Cell Surface, and Its Expression Correlates with the Disruption of Sertoli-Germ Cell Junctions but Not the Inter-Sertoli Tight Junction* , 1998, The Journal of Biological Chemistry.

[48]  M. Miller,et al.  The role of the benomyl metabolite carbendazim in benomyl-induced testicular toxicity. , 1997, Toxicology and applied pharmacology.

[49]  M. Nakai,et al.  Morphological changes in the rat Sertoli cell induced by the microtubule poison carbendazim. , 1994, Tissue & cell.

[50]  K. Boekelheide,et al.  Colchicine disrupts the cytoskeleton of rat testis seminiferous epithelium in a stage-dependent manner. , 1993, Biology of reproduction.

[51]  L. Strader,et al.  Acute and long-term effects of a single dose of the fungicide carbendazim (methyl 2-benzimidazole carbamate) on the male reproductive system in the rat. , 1992, Journal of andrology.

[52]  K. Boekelheide,et al.  The Sertoli cell cytoskeleton: a target for toxicant-induced germ cell loss. , 1989, Toxicology and applied pharmacology.