Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans
暂无分享,去创建一个
J. Eisfeldt | S. Catrina | I. Tapia-Páez | B. Gudbjornsson | P. Nikamo | Xiaowei Zheng | F. Taylan | Sailan Wang | Leena Laasonen | Leif Ejstrup | Lars Iversen | Ulla Lindqvist | Jessica J Alm | Raquel Vaz | Mona Ståhle
[1] W. Liao,et al. New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine. , 2021, The Journal of investigative dermatology.
[2] F. Fieschi,et al. NADPH Oxidases (NOX): An Overview from Discovery, Molecular Mechanisms to Physiology and Pathology , 2021, Antioxidants.
[3] F. Rivadeneira,et al. An ARHGAP25 variant links aberrant Rac1 function to early‐onset skeletal fragility , 2021, JBMR plus.
[4] L. Iversen,et al. Comorbidities in a Cohort of 66 Patients With Psoriatic Arthritis Mutilans—Results From the Nordic PAM Study , 2021, Frontiers in Medicine.
[5] H. Takayanagi. RANKL as the master regulator of osteoclast differentiation , 2021, Journal of Bone and Mineral Metabolism.
[6] L. Padyukov,et al. HLA-B*27 is significantly enriched in Nordic patients with psoriatic arthritis mutilans. , 2020, Clinical and experimental rheumatology.
[7] Ju-Young Kim,et al. Dual Oxidase Maturation Factor 1 Positively Regulates RANKL-Induced Osteoclastogenesis via Activating Reactive Oxygen Species and TRAF6-Mediated Signaling , 2020, International journal of molecular sciences.
[8] Kyung-Hyun Park-Min,et al. The M-CSF receptor in osteoclasts and beyond , 2020, Experimental & Molecular Medicine.
[9] D. Haudenschild,et al. NADPH oxidases in bone and cartilage homeostasis and disease: A promising therapeutic target , 2020, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[10] Shenshu Yang,et al. ROS and diseases: role in metabolism and energy supply , 2019, Molecular and Cellular Biochemistry.
[11] F. Perrotta,et al. Occult axial involvement in patients with psoriatic arthritis mutilans: a case report. , 2019, Reumatismo.
[12] Renée A Beach,et al. Twenty Years Without Treatment: A Presentation of Arthritis Mutilans With Psoriasis , 2019, Journal of cutaneous medicine and surgery.
[13] Gregory M. Cooper,et al. CADD: predicting the deleteriousness of variants throughout the human genome , 2018, Nucleic Acids Res..
[14] B. Lardy,et al. Reactive oxygen species and NADPH oxidase 4 involvement in osteoarthritis , 2018, Experimental Gerontology.
[15] Xuejun Zhang,et al. A catalog of potential putative functional variants in psoriasis genome-wide association regions , 2018, PloS one.
[16] Zhong-Bao Yang,et al. Upregulation of NOX2 and NOX4 Mediated by TGF-β Signaling Pathway Exacerbates Cerebral Ischemia/Reperfusion Oxidative Stress Injury , 2018, Cellular Physiology and Biochemistry.
[17] I. McInnes,et al. Psoriatic arthritis: tissue-directed inflammation? , 2018, Clinical Rheumatology.
[18] Xing Chen,et al. Key Triggers of Osteoclast-Related Diseases and Available Strategies for Targeted Therapies: A Review , 2017, Front. Med..
[19] S. Dikalov,et al. Electron Paramagnetic Resonance Measurements of Reactive Oxygen Species by Cyclic Hydroxylamine Spin Probes. , 2017, Antioxidants & redox signaling.
[20] Pall I. Olason,et al. SweGen: a whole-genome data resource of genetic variability in a cross-section of the Swedish population , 2017, European Journal of Human Genetics.
[21] Anders E. Halager,et al. Sequencing and de novo assembly of 150 genomes from Denmark as a population reference , 2017, Nature.
[22] Z. Graham,et al. Spinal Cord Injury Leads to Hyperoxidation and Nitrosylation of Skeletal Muscle Ryanodine Receptor-1 Associated with Upregulation of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 4. , 2017, Journal of neurotrauma.
[23] Pall I. Olason,et al. TIDDIT, an efficient and comprehensive structural variant caller for massive parallel sequencing data , 2017, F1000Research.
[24] L. Iversen,et al. Disease activity in and quality of life of patients with psoriatic arthritis mutilans: the Nordic PAM Study , 2017, Scandinavian journal of rheumatology.
[25] B. Steventon,et al. A Versatile Mounting Method for Long Term Imaging of Zebrafish Development. , 2017, Journal of visualized experiments : JoVE.
[26] L. Saso,et al. Detection of Reactive Oxygen and Nitrogen Species by Electron Paramagnetic Resonance (EPR) Technique , 2017, Molecules.
[27] H. Saya,et al. Methotrexate inhibits osteoclastogenesis by decreasing RANKL-induced calcium influx into osteoclast progenitors , 2016, Journal of Bone and Mineral Metabolism.
[28] C. Brightling,et al. Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD , 2016, Respiratory Research.
[29] T. Mak,et al. TNF and ROS Crosstalk in Inflammation. , 2016, Trends in cell biology.
[30] Wenjun Xie,et al. Excess TGF-β mediates muscle weakness associated with bone metastases in mice , 2015, Nature Medicine.
[31] J. Bidart,et al. NADPH oxidase DUOX1 promotes long-term persistence of oxidative stress after an exposure to irradiation , 2015, Proceedings of the National Academy of Sciences.
[32] K. Schröder. NADPH oxidases in bone homeostasis and osteoporosis , 2014, Cellular and Molecular Life Sciences.
[33] J. Gran,et al. Psoriatic arthritis mutilans (PAM) in the Nordic countries: demographics and disease status. The Nordic PAM study , 2013, Scandinavian journal of rheumatology.
[34] A. Zullo,et al. Psoriatic Arthritis Mutilans: Case Series and Literature Review , 2013, The Journal of Rheumatology.
[35] J. Hošek,et al. TNF-α signalling and inflammation: interactions between old acquaintances , 2013, Inflammation Research.
[36] S. Barman,et al. From form to function: the role of Nox4 in the cardiovascular system , 2012, Front. Physio..
[37] B. Crestani,et al. NOX4/NADPH oxidase expression is increased in pulmonary fibroblasts from patients with idiopathic pulmonary fibrosis and mediates TGFβ1-induced fibroblast differentiation into myofibroblasts , 2010, Thorax.
[38] J. -. Park,et al. TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL , 2010, Cell Death and Differentiation.
[39] Y. Gorin,et al. Colony-stimulating factor-1 (CSF-1) directly inhibits receptor activator of nuclear factor-{kappa}B ligand (RANKL) expression by osteoblasts. , 2009, Endocrinology.
[40] K. Griendling,et al. Nox proteins in signal transduction. , 2009, Free radical biology & medicine.
[41] A. Gottlieb,et al. Treatment recommendations for psoriatic arthritis , 2008, Annals of the rheumatic diseases.
[42] G. Novelli,et al. Haplotypes in SLC24A5 Gene as Ancestry Informative Markers in Different Populations , 2008, Current genomics.
[43] Soo Young Lee,et al. A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation. , 2005, Blood.
[44] Steven Henikoff,et al. SIFT: predicting amino acid changes that affect protein function , 2003, Nucleic Acids Res..
[45] M. Fraaije,et al. University of Groningen Crystal structures and atomic model of NADPH oxidase , 2017 .
[46] V. Wright,et al. Psoriatic arthritis. , 1983, Clinics in rheumatic diseases.