Percutaneous vertebroplasty treatment of steroid-induced osteoporotic compression fractures.

This report describes the case of a woman in whom multiple compression fractures of the lower thoracic and lumbar spine occurred in association with long-term corticosteroid therapy for systemic lupus erythematosus. Pain markedly limited the patient's mobility and daily activities, and conservative therapy with bracing and narcotic analgesics gave little improvement. Affected vertebrae were treated with polymethylmethacrylate, introduced percutaneously under fluoroscopic guidance. The resulting reinforcement of the fractured vertebral bodies eliminated the pain and the need for narcotic analgesics. The utilization of percutaneous verterbroplasty as a therapeutic alternative for the treatment of pain resulting from osteoporotic compression fractures is described.

[1]  F. Mornex,et al.  Vertébroplastie percutanée dans le traitement des métastases: technique et résultats , 1989 .

[2]  A. Gangi,et al.  Percutaneous vertebroplasty guided by a combination of CT and fluoroscopy. , 1994, AJNR. American journal of neuroradiology.

[3]  K. Harrington.  Anterior decompression and stabilization of the spine as a treatment for vertebral collapse and spinal cord compression from metastatic malignancy. , 1988, Clinical orthopaedics and related research.

[4]  M. Petri.  Musculoskeletal complications of systemic lupus erythematosus in the Hopkins Lupus Cohort: an update. , 1995, Arthritis care and research : the official journal of the Arthritis Health Professions Association.

[5]  H. Deramond,et al.  [Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty]. , 1987, Neuro-Chirurgie.

[6]  G. Cybulski.  Methods of Surgical Stabilization for Metastatic Disease of the Spine , 1989, Neurosurgery.

[7]  E. Lins,et al.  Vertebral hemangioma: retrograde embolization-stabilization with methyl methacrylate. , 1987, Surgical neurology.

[8]  J. Chiras,et al.  Spinal metastases: indications for and results of percutaneous injection of acrylic surgical cement. , 1996, Radiology.

[9]  R. Assaker,et al.  Percutaneous vertebroplasty for osteolytic metastases and myeloma: effects of the percentage of lesion filling and the leakage of methyl methacrylate at clinical follow-up. , 1996, Radiology.

[10]  P. Fardellone,et al.  Percutaneous vertebroplasty with acrylic cement in the treatment of osteoporotic vertebral crush fracture syndrome , 1991 .

[11]  R. O'Donnell,et al.  Recurrence of giant-cell tumors of the long bones after curettage and packing with cement. , 1994, The Journal of bone and joint surgery. American volume.

[12]  S. H. Kan,et al.  Epidemiology of vertebral fractures in women. , 1989, American journal of epidemiology.

[13]  P. McCormack,et al.  Treatment of neoplastic epidural cord compression by vertebral body resection and stabilization. , 1985, Journal of neurosurgery.

[14]  D F Kallmes,et al.  Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects. , 1997, AJNR. American journal of neuroradiology.