Phosphoregulation of the oncogenic protein regulator of cytokinesis 1 (PRC1) by the atypical CDK16/CCNY complex

[1]  W. Huber,et al.  Proteome-wide identification of ubiquitin interactions using UbIA-MS , 2018, Nature Protocols.

[2]  T. Kirchner,et al.  PRC1: Linking Cytokinesis, Chromosomal Instability, and Cancer Evolution. , 2017, Trends in cancer.

[3]  U. Rix,et al.  Dabrafenib inhibits the growth of BRAF‐WT cancers through CDK16 and NEK9 inhibition , 2017, Molecular oncology.

[4]  J. Clotet,et al.  Intertwined control of the cell cycle and nucleocytoplasmic transport by the cyclin-dependent kinase Pho85 and RanGTPase Gsp1 in Saccharomyces cerevisiae. , 2018, Microbiological research.

[5]  P. Cramer,et al.  CDK9-dependent RNA polymerase II pausing controls transcription initiation , 2017, eLife.

[6]  Pengpeng Liu,et al.  Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression , 2017, Journal of Experimental & Clinical Cancer Research.

[7]  K. Hui,et al.  Atypical regulators of Wnt/β-catenin signaling as potential therapeutic targets in Hepatocellular Carcinoma , 2017, Experimental biology and medicine.

[8]  Jing He,et al.  Protein Regulator of Cytokinesis PRC1 Confers Chemoresistance and Predicts an Unfavorable Postoperative Survival of Hepatocellular Carcinoma Patients , 2017, Journal of Cancer.

[9]  Yu Cao,et al.  Elevated PRC1 in gastric carcinoma exerts oncogenic function and is targeted by piperlongumine in a p53‐dependent manner , 2017, Journal of cellular and molecular medicine.

[10]  T. Sharpe,et al.  Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16 , 2017, The Biochemical journal.

[11]  A. Burlingame,et al.  Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen , 2016, Proceedings of the National Academy of Sciences.

[12]  Y. A. Zeng,et al.  Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells , 2016, PLoS genetics.

[13]  W. Hong,et al.  The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway , 2016, Gut.

[14]  K. Shokat,et al.  Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. , 2016, Journal of medicinal chemistry.

[15]  Haiyuan Liu,et al.  Cyclin Y regulates the proliferation, migration, and invasion of ovarian cancer cells via Wnt signaling pathway , 2016, Tumor Biology.

[16]  P. Stephens,et al.  A metastatic colon adenocarcinoma harboring BRAF V600E has a durable major response to dabrafenib/trametinib and chemotherapy , 2015, OncoTargets and therapy.

[17]  M. Hendzel,et al.  Sequential fractionation and isolation of subcellular proteins from tissue or cultured cells , 2015, MethodsX.

[18]  Rosanne Raso,et al.  Changing a paradigm. , 2015, Nursing management.

[19]  Jeroen A. A. Demmers,et al.  The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1 , 2015, Scientific Reports.

[20]  K. Shokat,et al.  SR protein kinases promote splicing of nonconsensus introns , 2015, Nature Structural &Molecular Biology.

[21]  V. Kalscheuer,et al.  Cyclin Y phosphorylation- and 14-3-3-binding-dependent activation of PCTAIRE-1/CDK16 , 2015, The Biochemical journal.

[22]  W. Wurst,et al.  Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells , 2015, Nature Biotechnology.

[23]  Y. Ishihama,et al.  PCTK1 Regulates Integrin-Dependent Spindle Orientation via Protein Kinase A Regulatory Subunit KAP0 and Myosin X , 2015, Molecular and Cellular Biology.

[24]  B. Styp-Rekowska,et al.  RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification , 2014, Oncotarget.

[25]  John Calvin Reed,et al.  PCTAIRE1 phosphorylates p27 and regulates mitosis in cancer cells. , 2014, Cancer research.

[26]  Yuuki Imai,et al.  Pctaire1/Cdk16 promotes skeletal myogenesis by inducing myoblast migration and fusion , 2014, FEBS letters.

[27]  F. Cross,et al.  Method for identifying phosphorylated substrates of specific cyclin/cyclin-dependent kinase complexes , 2014, Proceedings of the National Academy of Sciences.

[28]  K. Shokat,et al.  The logic and design of analog-sensitive kinases and their small molecule inhibitors. , 2014, Methods in enzymology.

[29]  A. Hilliker,et al.  In Vivo Interaction Proteomics Reveal a Novel p38 Mitogen-Activated Protein Kinase/Rack1 Pathway Regulating Proteostasis in Drosophila Muscle , 2013, Molecular and Cellular Biology.

[30]  K. Shokat,et al.  Staurosporine-derived inhibitors broaden the scope of analog-sensitive kinase technology. , 2013, Journal of the American Chemical Society.

[31]  David A. Scott,et al.  Genome engineering using the CRISPR-Cas9 system , 2013, Nature Protocols.

[32]  F. Quiocho,et al.  New Structural Insights into Phosphorylation-free Mechanism for Full Cyclin-dependent Kinase (CDK)-Cyclin Activity and Substrate Recognition* , 2013, The Journal of Biological Chemistry.

[33]  S. Finkbeiner,et al.  Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology. , 2013, ACS chemical biology.

[34]  T. Kapoor,et al.  Marking and Measuring Single Microtubules by PRC1 and Kinesin-4 , 2013, Cell.

[35]  A. Porter,et al.  Chemical genetic analyses of quantitative changes in Cdk1 activity during the human cell cycle. , 2013, Human molecular genetics.

[36]  T. Surrey,et al.  End-binding proteins and Ase1/PRC1 define local functionality of structurally distinct parts of the microtubule cytoskeleton. , 2013, Trends in cell biology.

[37]  Bill X. Huang,et al.  Integration of phosphoproteomic, chemical, and biological strategies for the functional analysis of targeted protein phosphorylation , 2013, Proteomics.

[38]  Johannes Griss,et al.  The Proteomics Identifications (PRIDE) database and associated tools: status in 2013 , 2012, Nucleic Acids Res..

[39]  J. Rainer,et al.  Orphan kinases turn eccentric , 2012, Cell cycle.

[40]  Nurhan Özlü,et al.  Plk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis , 2012, Molecular biology of the cell.

[41]  Jun O. Liu,et al.  Brain-selective Kinase 2 (BRSK2) Phosphorylation on PCTAIRE1 Negatively Regulates Glucose-stimulated Insulin Secretion in Pancreatic β-Cells* , 2012, The Journal of Biological Chemistry.

[42]  M. Brown,et al.  Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial , 2012, The Lancet.

[43]  S. Geley,et al.  Cyclin-Dependent Kinase 16/PCTAIRE Kinase 1 Is Activated by Cyclin Y and Is Essential for Spermatogenesis , 2011, Molecular and Cellular Biology.

[44]  Chao Zhang,et al.  Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. , 2011, Molecular cell.

[45]  T. Mitchison,et al.  KIF4 Regulates Midzone Length during Cytokinesis , 2011, Current Biology.

[46]  Christopher P. Arthur,et al.  Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein , 2010, Cell.

[47]  Søren Brunak,et al.  Cyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis results , 2009, Nucleic Acids Res..

[48]  Hongwei Wang,et al.  Lentivirus-mediated knockdown of cyclin Y (CCNY) inhibits glioma cell proliferation. , 2009, Oncology research.

[49]  M. Boutros,et al.  Cell cycle control of wnt receptor activation. , 2009, Developmental cell.

[50]  A. Cole.  PCTK Proteins: The Forgotten Brain Kinases? , 2009, Neurosignals.

[51]  U. Kutay,et al.  Orchestrating nuclear envelope disassembly and reassembly during mitosis , 2009, Nature Reviews Molecular Cell Biology.

[52]  M. Barbacid,et al.  Cell cycle, CDKs and cancer: a changing paradigm , 2009, Nature Reviews Cancer.

[53]  M. Glotzer,et al.  The 3Ms of central spindle assembly: microtubules, motors and MAPs , 2009, Nature Reviews Molecular Cell Biology.

[54]  Karl A. Merrick,et al.  Distinct activation pathways confer cyclin-binding specificity on Cdk1 and Cdk2 in human cells. , 2008, Molecular cell.

[55]  M. Mann,et al.  MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.

[56]  K. Shokat,et al.  Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates , 2008, Proceedings of the National Academy of Sciences.

[57]  Yusuke Nakamura,et al.  Oncogenic role of MPHOSPH1, a cancer-testis antigen specific to human bladder cancer. , 2008, Cancer research.

[58]  Y. Abe,et al.  A mitotic kinase TOPK enhances Cdk1/cyclin B1-dependent phosphorylation of PRC1 and promotes cytokinesis. , 2007, Journal of molecular biology.

[59]  Renming Hu,et al.  Mitotic phosphorylation of PRC1 at Thr470 is required for PRC1 oligomerization and proper central spindle organization , 2007, Cell Research.

[60]  Yusuke Nakamura,et al.  Oncogenic Role of MPHOSPH1, a Cancer-Testis Antigen Specific to Human Bladder Cancer , 2007 .

[61]  Stéphane Larochelle,et al.  Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. , 2007, Molecular cell.

[62]  E. Nigg,et al.  Choice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1 , 2007, Nature Cell Biology.

[63]  Yusuke Nakamura,et al.  Elevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells , 2007, Cancer science.

[64]  Ke Gong,et al.  Pctaire1 Phosphorylates N-Ethylmaleimide-sensitive Fusion Protein , 2006, Journal of Biological Chemistry.

[65]  D. Stephens,et al.  PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport , 2005, Journal of Cell Science.

[66]  Wei Jiang,et al.  Cell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[67]  G. Crooks,et al.  WebLogo: a sequence logo generator. , 2004, Genome research.

[68]  Yusuke Nakamura,et al.  Genome-wide cDNA microarray analysis of gene expression profiles in pancreatic cancers using populations of tumor cells and normal ductal epithelial cells selected for purity by laser microdissection , 2004, Oncogene.

[69]  K. Shokat,et al.  Inhibitor scaffolds as new allele specific kinase substrates. , 2002, Journal of the American Chemical Society.

[70]  T. Hunt,et al.  Regulation of the CDK-related protein kinase PCTAIRE-1 and its possible role in neurite outgrowth in Neuro-2A cells. , 2002, Journal of cell science.

[71]  F. Sladeczek,et al.  Multiple Subcellular Localizations of PCTAIRE-1 in Brain , 2000, Molecular and Cellular Neuroscience.

[72]  Peter G. Schultz,et al.  A chemical switch for inhibitor-sensitive alleles of any protein kinase , 2000, Nature.

[73]  S. Ferrari,et al.  PCTAIRE-1: characterization, subcellular distribution, and cell cycle-dependent kinase activity. , 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[74]  D. Wolgemuth,et al.  The cellular distribution and kinase activity of the Cdk family member Pctaire1 in the adult mouse brain and testis suggest functions in differentiation. , 1999, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[75]  M. Okada,et al.  PCTAIRE 2, a Cdc2-related serine/threonine kinase, is predominantly expressed in terminally differentiated neurons. , 1997, European journal of biochemistry.

[76]  D. Wolgemuth,et al.  Cdk family genes are expressed not only in dividing but also in terminally differentiated mouse germ cells, suggesting their possible function during both cell division and differentiation , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[77]  真二 土田,et al.  『甲殻類研究の現状と展望』を終えて(ミニシンポジウム : 『甲殻類研究の現状と展望』を終えて) , 1995 .