The spectral/hp element modelling of steady flow in non‐planar double bends

The purpose of this study is to better understand steady flow in three‐dimensional non‐planar double bend geometries which are chosen to loosely model a right coronary or femoral artery, neglecting branches. The knowledge gained from idealized geometries can subsequently be applied to anatomically correct geometries. The three‐dimensional computations of steady flows in planar and non‐planar double bends at Reynolds numbers of 125 and 500 were performed using a high accuracy, spectral/hp element Navier–Stokes solver. In this study, we analyse the haemodynamics in terms of various mechanical factors (i.e. axial velocity, secondary flows, vorticity and coherent vortical structures). Although the effects of curvature and non‐planarity on the flows are complex and often non‐intuitive, from the numerical results, we can simplify and anticipate the secondary flow patterns, and by associations the wall shear stress distribution, in various double bend geometries with different non‐planarities at physiological Reynolds number (100⩽Re⩽500). Non‐planarity has the biggest effects on mixing and swirling of flow as observed through the coherent vortical structures and asymmetric secondary flow streamlines. Copyright © 2007 John Wiley & Sons, Ltd.

[1]  J. Farey,et al.  XXXVI. On blasting with gunpowder , 1804 .

[2]  John Eustice,et al.  Flow of water in curved pipes , 1910 .

[3]  W. R. Dean LXXXVII. Note on the motion of fluid in a sinuous channel , 1927 .

[4]  W. R. Dean XVI. Note on the motion of fluid in a curved pipe , 1927 .

[5]  W. R. Dean LXXII. The stream-line motion of fluid in a curved pipe (Second paper) , 1928 .

[6]  D. A. Mcdonald Blood flow in arteries , 1974 .

[7]  R. Schroter,et al.  Atheroma and arterial wall shear - Observation, correlation and proposal of a shear dependent mass transfer mechanism for atherogenesis , 1971, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[8]  W. R. Wagner,et al.  Correspondence: Grain boundaries in thin-film bicrystals of surface-reactive metals prepared by vacuum welding , 1974 .

[9]  R. Ross,et al.  Hyperlipidemia and atherosclerosis. , 1976, Science.

[10]  J. Cornhill,et al.  The effect of the duration of cholesterol feeding on the development of sudanophilic lesions in the rabbit aorta. , 1976, Atherosclerosis.

[11]  Bierman El Atherosclerosis and aging. , 1978 .

[12]  P. Peronneau,et al.  Flow in the thoracic aorta. , 1979, Cardiovascular research.

[13]  K B Chandran,et al.  Physiological pulsatile flow experiments in a model of the human aortic arch. , 1982, Journal of biomechanics.

[14]  R. Nerem,et al.  Model study of flow in curved and planar arterial bifurcations. , 1982, Cardiovascular research.

[15]  P K Paulsen,et al.  Three-dimensional visualization of velocity profiles in the ascending aorta in dogs, measured with a hot-film anemometer. , 1983, Journal of biomechanics.

[16]  H N Sabbah,et al.  Patterns of flow in the left coronary artery. , 1984, Journal of biomechanical engineering.

[17]  R. Nerem,et al.  An experimental study of coronary artery fluid mechanics. , 1985, Journal of biomechanical engineering.

[18]  D. Ku,et al.  Pulsatile Flow and Atherosclerosis in the Human Carotid Bifurcation: Positive Correlation between Plaque Location and Low and Oscillating Shear Stress , 1985, Arteriosclerosis.

[19]  Y. Cho,et al.  Fluid dynamic study in a femoral artery branch casting of man with upstream main lumen curvature for steady flow. , 1985, Journal of biomechanical engineering.

[20]  D. Small,et al.  George Lyman Duff memorial lecture. Progression and regression of atherosclerotic lesions. Insights from lipid physical biochemistry. , 1988, Arteriosclerosis.

[21]  L. Back,et al.  Flow measurements in an atherosclerotic curved, tapered femoral artery model of man. , 1988, Journal of biomechanical engineering.

[22]  L. Back,et al.  Flow measurements in a human femoral artery model with reverse lumen curvature. , 1988, Journal of biomechanical engineering.

[23]  K. Perktold,et al.  Wall shear stress distribution in the human carotid siphon during pulsatile flow. , 1988, Journal of biomechanics.

[24]  T. Carew,et al.  Initiation of atherosclerotic lesions in cholesterol-fed rabbits. I. Focal increases in arterial LDL concentration precede development of fatty streak lesions. , 1989, Arteriosclerosis.

[25]  K. Chandran,et al.  Functional chiral asymmetry in descending thoracic aorta. , 1990, Circulation.

[26]  Fazle Hussain,et al.  Understanding Turbulence Via Vortex Dynamics , 1992 .

[27]  Y. Cho,et al.  Numerical studies of three-dimensional arterial flows in reverse curvature geometry: Part I--Peak flow. , 1993, Journal of biomechanical engineering.

[28]  Guang-Zhong Yang,et al.  Helical and Retrograde Secondary Flow Patterns in the Aortic Arch Studied by Three‐Directional Magnetic Resonance Velocity Mapping , 1993, Circulation.

[29]  J. Haselgrove,et al.  A MRI bolus tagging method for observing helical flow in the descending aorta , 1994, Magnetic resonance in medicine.

[30]  M. Davies,et al.  Diabetes mellitus and experimental vein graft structure and function. , 1994, Journal of vascular surgery.

[31]  P Boesiger,et al.  Hemodynamics in the abdominal aorta: a comparison of in vitro and in vivo measurements. , 1994, Journal of applied physiology.

[32]  V. Venkatakrishnan,et al.  A 3D AGGLOMERATION MULTIGRID SOLVER FOR THE REYNOLDS-AVERAGED NAVIER-STOKES EQUATIONS ON UNSTRUCTURED MESHES , 1995 .

[33]  P. Davies,et al.  Flow-mediated endothelial mechanotransduction. , 1995, Physiological reviews.

[34]  Jinhee Jeong,et al.  On the identification of a vortex , 1995, Journal of Fluid Mechanics.

[35]  K. T. Scott,et al.  Non-planar curvature and branching of arteries and non-planar-type flow , 1996, Proceedings of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[36]  C F Dewey,et al.  Shear stress gradients remodel endothelial monolayers in vitro via a cell proliferation-migration-loss cycle. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[37]  M. Gooden,et al.  Identification of predictors for lower extremity vein graft stenosis. , 1997, American journal of surgery.

[38]  S. Sherwin,et al.  The influence of out-of-plane geometry on the flow within a distal end-to-side anastomosis. , 2000, Journal of biomechanical engineering.

[39]  L. Szczech,et al.  Long-term outcomes of revascularization for peripheral vascular disease in end-stage renal disease patients. , 2001, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[40]  Xi-yun Lu,et al.  Breaking symmetry in non-planar bifurcations: distribution of flow and wall shear stress. , 2002, Biorheology.

[41]  S. Wada,et al.  Theoretical Prediction of Low-Density Lipoproteins Concentration at the Luminal Surface of an Artery with a Multiple Bend , 2002, Annals of Biomedical Engineering.

[42]  S Giordana,et al.  Local and global geometric influence on steady flow in distal anastomoses of peripheral bypass grafts. , 2005, Journal of biomechanical engineering.

[43]  L. Wilkins New Investigator Awards , 2005 .

[44]  R. Pitt Numerical simulation of fluid mechanical phenomena in idealised physiological geometries : stenosis and double bend , 2006 .