RANK/RANKL Axis in Melanoma
暂无分享,去创建一个
D. Heymann | K. Mori | K. Ando | F. Lézot
[1] J. Penninger,et al. Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit , 2011, Proceedings of the National Academy of Sciences.
[2] A. Haeseler,et al. Central control of fever and female body temperature by RANKL/RANK , 2009, Nature.
[3] B. Pitard,et al. Therapeutic efficacy of soluble receptor activator of nuclear factor-kappa B-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma , 2010 .
[4] M. Mikkola. TNF superfamily in skin appendage development. , 2008, Cytokine & growth factor reviews.
[5] D. Heymann,et al. Receptor activator of nuclear factor-kappaB ligand (RANKL) directly modulates the gene expression profile of RANK-positive Saos-2 human osteosarcoma cells. , 2007, Oncology reports.
[6] B. Pitard,et al. Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption. , 2007, Cancer research.
[7] J. Penninger,et al. RANK signals from CD4+3− inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla , 2007, The Journal of Experimental Medicine.
[8] B. Le Goff,et al. DU145 human prostate cancer cells express functional receptor activator of NFkappaB: new insights in the prostate cancer bone metastasis process. , 2007, Bone.
[9] B. Le Goff,et al. Human osteosarcoma cells express functional receptor activator of nuclear factor‐kappa B , 2007, The Journal of pathology.
[10] M. Dimopoulos,et al. Abnormal bone remodeling process is due to an imbalance in the receptor activator of nuclear factor–κB ligand (RANKL)/osteoprotegerin (OPG) axis in patients with solid tumors metastatic to the skeleton , 2007, Acta oncologica.
[11] M. Padrines,et al. OPG/membranous--RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradation. , 2006, Bone.
[12] A. Potti,et al. Expression of RANKL/RANK/OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation , 2006, Cancer.
[13] S. M. Sims,et al. Regulation of cancer cell migration and bone metastasis by RANKL , 2006, Nature.
[14] B. Abrahamsen,et al. Technology evaluation: denosumab, Amgen. , 2005, Current opinion in molecular therapeutics.
[15] E. Schwarz,et al. The effects of RANK blockade and osteoclast depletion in a model of pure osteoblastic prostate cancer metastasis in bone , 2005, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[16] R. Vessella,et al. Osteoprotegerin in prostate cancer bone metastasis. , 2005, Cancer research.
[17] M. Padrines,et al. Osteolytic bone diseases: physiological analogues of bone resorption effectors as alternative therapeutic tools. , 2005, Drug discovery today.
[18] S. Théoleyre,et al. The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling. , 2004, Cytokine & growth factor reviews.
[19] A. Ohazama,et al. Opg, Rank, and Rankl in Tooth Development: Co-ordination of Odontogenesis and Osteogenesis , 2004, Journal of dental research.
[20] W. Dougall,et al. Soluble receptor activator of nuclear factor kappaB Fc diminishes prostate cancer progression in bone. , 2003, Cancer research.
[21] D. Goltzman. Osteolysis and cancer. , 2001, The Journal of clinical investigation.
[22] A. Mizokami,et al. Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone. , 2001, The Journal of clinical investigation.
[23] R. Vessella,et al. Osteoprotegerin and rank ligand expression in prostate cancer. , 2001, Urology.
[24] D. Lacey,et al. The Osteoclast Differentiation Factor Osteoprotegerin-Ligand Is Essential for Mammary Gland Development , 2000, Cell.
[25] W. Dougall,et al. RANK is essential for osteoclast and lymph node development. , 1999, Genes & development.
[26] S. Morony,et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis , 1999, Nature.
[27] D. Lacey,et al. Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.
[28] G Shimamoto,et al. Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density , 1997, Cell.
[29] J. Penninger,et al. Novel functions of RANK(L) signaling in the immune system. , 2010, Advances in experimental medicine and biology.
[30] C. Brisken,et al. What signals operate in the mammary niche? , 2008, Breast disease.
[31] W. Dougall,et al. RANKL acts directly on RANK‐expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes , 2008, The Prostate.
[32] P. Kostenuik,et al. Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis , 2007, Clinical & Experimental Metastasis.
[33] D. Heymann,et al. RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells. , 2006, International journal of oncology.