Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

[1]  H. Okano,et al.  Single-cell trajectory analysis of human homogenous neurons carrying a rare RELN variant , 2018, Translational Psychiatry.

[2]  T. Nabeshima,et al.  Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes , 2018, Glia.

[3]  K. Sakimura,et al.  Dorsal Forebrain-Specific Deficiency of Reelin-Dab1 Signal Causes Behavioral Abnormalities Related to Psychiatric Disorders , 2017, Cerebral cortex.

[4]  Jen Q. Pan,et al.  The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression , 2017, Journal of neurochemistry.

[5]  M. Itokawa,et al.  High-resolution copy number variation analysis of schizophrenia in Japan , 2017, Molecular Psychiatry.

[6]  K. Nakajima,et al.  Reelin and Neuropsychiatric Disorders , 2016, Front. Cell. Neurosci..

[7]  A. Vita,et al.  Schizophrenia , 2016, The Lancet.

[8]  H. Shoji,et al.  Mice that lack the C-terminal region of Reelin exhibit behavioral abnormalities related to neuropsychiatric disorders , 2016, Scientific Reports.

[9]  Zhening Liu,et al.  Identification of RELN variation p.Thr3192Ser in a Chinese family with schizophrenia , 2016, Scientific Reports.

[10]  T. Nabeshima,et al.  Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex , 2016, Neuropsychopharmacology.

[11]  Christopher S. Poultney,et al.  Synaptic, transcriptional, and chromatin genes disrupted in autism , 2014, Nature.

[12]  Dan J Stein,et al.  The neurobiology of methamphetamine induced psychosis , 2014, Front. Hum. Neurosci..

[13]  E. Banks,et al.  De novo mutations in schizophrenia implicate synaptic networks , 2014, Nature.

[14]  Daniele Merico,et al.  Pathogenic rare copy number variants in community-based schizophrenia suggest a potential role for clinical microarrays. , 2013, Human molecular genetics.

[15]  Robert Lalonde,et al.  Neurobehavioral performances and brain regional metabolism in Dab1 scm (scrambler) mutant mice , 2013, Behavioural Brain Research.

[16]  S. Fatemi,et al.  The involvement of Reelin in neurodevelopmental disorders , 2013, Neuropharmacology.

[17]  T. Nabeshima,et al.  Evaluation of emotional behaviors in young offspring of C57BL/6J mice after gestational and/or perinatal exposure to nicotine in six different time-windows , 2013, Behavioural Brain Research.

[18]  M. Surani,et al.  Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice , 2013, Glia.

[19]  B. Barak,et al.  Evidence for a Developmental Role for TLR4 in Learning and Memory , 2012, PloS one.

[20]  J. Rogers,et al.  Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. , 2011, Learning & memory.

[21]  P. Penzes,et al.  Dendritic spine pathology in neuropsychiatric disorders , 2011, Nature Neuroscience.

[22]  M. Frotscher,et al.  Region‐specific alteration of GABAergic markers in the brain of heterozygous reeler mice , 2011, The European journal of neuroscience.

[23]  K. Kaibuchi,et al.  Dysfunction of dopamine release in the prefrontal cortex of dysbindin deficient sandy mice: An in vivo microdialysis study , 2010, Neuroscience Letters.

[24]  A. Sawa,et al.  Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood , 2010, Behavioural Brain Research.

[25]  S. Haber,et al.  The Reward Circuit: Linking Primate Anatomy and Human Imaging , 2010, Neuropsychopharmacology.

[26]  N. Perrone-Bizzozero,et al.  Schizophrenia-like GABAergic gene expression deficits in cerebellar Golgi cells from rats chronically exposed to low-dose phencyclidine , 2009, Neurochemistry International.

[27]  T. Nabeshima,et al.  Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood , 2009, Neuroscience Research.

[28]  Juan Bustillo,et al.  Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia patients. , 2008, The American journal of psychiatry.

[29]  N. Andreasen,et al.  The Role of the Cerebellum in Schizophrenia , 2008, Biological Psychiatry.

[30]  Masao Ito.  Control of mental activities by internal models in the cerebellum , 2008, Nature Reviews Neuroscience.

[31]  K. Mikoshiba,et al.  The Extremely Conserved C-terminal Region of Reelin Is Not Necessary for Secretion but Is Required for Efficient Activation of Downstream Signaling* , 2007, Journal of Biological Chemistry.

[32]  Kazuhiko W. Nakamura,et al.  Disruption of reelin signaling attenuates methamphetamine‐induced hyperlocomotion , 2007, The European journal of neuroscience.

[33]  T. Nabeshima,et al.  Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex. , 2007, Learning & memory.

[34]  G. Laviola,et al.  Impulsivity–anxiety-related behavior and profiles of morphine-induced analgesia in heterozygous reeler mice , 2007, Brain Research.

[35]  J. Herz,et al.  Reelin, lipoprotein receptors and synaptic plasticity , 2006, Nature Reviews Neuroscience.

[36]  K. Kasai,et al.  Estimation of premorbid IQ in individuals with Alzheimer’s disease using Japanese ideographic script (Kanji) compound words: Japanese version of National Adult Reading Test , 2006, Psychiatry and clinical neurosciences.

[37]  E. Weeber,et al.  Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice , 2006, Neurobiology of Learning and Memory.

[38]  Paul J. Harrison,et al.  Cellular basis of reduced cortical reelin expression in schizophrenia. , 2006, The American journal of psychiatry.

[39]  S. Fatemi,et al.  GABAergic dysfunction in schizophrenia and mood disorders as reflected by decreased levels of glutamic acid decarboxylase 65 and 67 kDa and Reelin proteins in cerebellum , 2005, Schizophrenia Research.

[40]  J. Mariani,et al.  Neurobehavioral evaluation of Relnrl-orl mutant mice and correlations with cytochrome oxidase activity , 2004, Neuroscience Research.

[41]  W. Salinger,et al.  Behavioral phenotype of the reeler mutant mouse: effects of RELN gene dosage and social isolation. , 2003, Behavioral neuroscience.

[42]  John M. Davis,et al.  Methodological factors influencing measurement and processing of plasma reelin in humans , 2003, BMC Biochemistry.

[43]  Wim E Crusio,et al.  Agonistic Behavior and Unpredictable Chronic Mild Stress in Mice , 2003, Behavior genetics.

[44]  A. Goffinet,et al.  Reelin and brain development , 2003, Nature Reviews Neuroscience.

[45]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[46]  E. Costa,et al.  Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Yogesh K. Dwivedi,et al.  Decrease in reelin and glutamic acid decarboxylase67 (GAD67) expression in schizophrenia and bipolar disorder: a postmortem brain study. , 2000, Archives of general psychiatry.

[48]  A. Guidotti,et al.  Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[49]  D. Lewis,et al.  Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. , 2000, Archives of general psychiatry.

[50]  Joachim Herz,et al.  Direct Binding of Reelin to VLDL Receptor and ApoE Receptor 2 Induces Tyrosine Phosphorylation of Disabled-1 and Modulates Tau Phosphorylation , 1999, Neuron.

[51]  Yogesh K. Dwivedi,et al.  The phenotypic characteristics of heterozygous reeler mouse. , 1999, Neuroreport.

[52]  Jonathan A. Cooper,et al.  Reelin-induced tryosine phosphorylation of Disabled 1 during neuronal positioning , 1999 .

[53]  K. Mikoshiba,et al.  A truncated Reelin protein is produced but not secreted in the 'Orleans' reeler mutation (Reln[rl-Orl]). , 1997, Brain research. Molecular brain research.

[54]  K. Mikoshiba,et al.  Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody , 1997, The Journal of Neuroscience.

[55]  J. Krystal,et al.  Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[56]  Y. Hayashizaki,et al.  Dysfunction of the Orleans reeler gene arising from exon skipping due to transposition of a full-length copy of an active L1 sequence into the skipped exon. , 1996, Human molecular genetics.

[57]  D. Sulzer,et al.  Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[58]  M. Seike,et al.  The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons , 1995, Neuron.