Overweight, obesity and fat distribution in 50- to 64-year-old participants in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Abstract Objective: To describe anthropometric characteristics of participants of the European Prospective Investigation into Cancer and Nutrition (EPIC). Design: A cross-sectional analysis of baseline data of a European prospective cohort study. Subjects: This analysis includes study populations from 25 centres in nine European countries. The British populations comprised both a population-based and a ‘health-conscious’ group. The analysis was restricted to 83 178 men and 163 851 women aged 50–64 years, this group being represented in all centres. Methods: Anthropometric examinations were undertaken by trained observers using standardised methods and included measurements of weight, height, and waist and hip circumferences. In the ‘health-conscious’ group (UK), anthropometric measures were predicted from self-reports. Results: Except in the ‘health-conscious’ group (UK) and in the French centres, mean body mass index (BMI) exceeded 25.0 kg m-2. The prevalence of obesity (BMI≥30 kg m-2) varied from 8% to 40% in men, and from 5% to 53% in women, with high prevalences (>25%) in the centres from Spain, Greece, Ragusa and Naples (Italy) and the lowest prevalences (<10%) in the French centres and the ‘health-conscious’ group (UK). The prevalence of a large waist circumference or a high waist-to-hip ratio was high in centres from Spain, Greece, Ragusa and Naples (Italy) and among women from centres in Germany and Bilthoven (The Netherlands). Conclusions: Anthropometric measures varied considerably within the EPIC population. These data provide a strong base for further investigation of anthropometric measures in relation to the risk of chronic diseases, especially cancer.

[1]  N E Day,et al.  European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection , 2002, Public Health Nutrition.

[2]  F. Clavel-Chapelon,et al.  European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study: rationale, design and population characteristics , 2002, Public Health Nutrition.

[3]  G. Berglund,et al.  A prospective study of adiposity and all-cause mortality: the Malmö Diet and Cancer Study. , 2002, Obesity research.

[4]  J. Vioque,et al.  Influence of sociodemographic factors in the prevalence of obesity in Spain. The SEEDO'97 Study , 2001, European Journal of Clinical Nutrition.

[5]  M. Thun,et al.  Body mass index, height, and prostate cancer mortality in two large cohorts of adult men in the United States. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[6]  D. Williamson,et al.  Report from a Centers for Disease Control and Prevention Workshop on use of adult anthropometry for public health and primary health care. , 2001, The American journal of clinical nutrition.

[7]  A. Astrup,et al.  Obesity : Preventing and managing the global epidemic , 2000 .

[8]  E. Vartiainen,et al.  Trends in waist-to-hip ratio and its determinants in adults in Finland from 1987 to 1997. , 2000, The American journal of clinical nutrition.

[9]  J. L. Gutiérrez-Fisac,et al.  Increasing prevalence of overweight and obesity among Spanish adults, 1987–1997 , 2000, International Journal of Obesity.

[10]  J. Benichou,et al.  Body size and prostate cancer: a population-based case-control study in China. , 2000, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[11]  B Järvholm,et al.  Obesity, hypertension, and the risk of kidney cancer in men. , 2000, The New England journal of medicine.

[12]  M. Thun,et al.  Body mass index and colon cancer mortality in a large prospective study. , 2000, American journal of epidemiology.

[13]  J R Marshall,et al.  Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk. , 2000, American journal of epidemiology.

[14]  J. Tuomilehto,et al.  Educational level, relative body weight, and changes in their association over 10 years: an international perspective from the WHO MONICA Project. , 2000, American journal of public health.

[15]  J. Seidell,et al.  Obesity, insulin resistance and diabetes — a worldwide epidemic , 2000, British Journal of Nutrition.

[16]  B. Stoll Adiposity as a risk determinant for postmenopausal breast cancer , 2000, International Journal of Obesity.

[17]  E. Feskens,et al.  Underweight and overweight in relation to mortality among men aged 40-59 and 50-69 years: the Seven Countries Study. , 2000, American journal of epidemiology.

[18]  B Rosner,et al.  Waist circumference, waist:hip ratio, and risk of breast cancer in the Nurses' Health Study. , 1999, American journal of epidemiology.

[19]  R. Shore,et al.  Body fat distribution and obesity in pre- and postmenopausal breast cancer. , 1999, International journal of epidemiology.

[20]  E. Ford Body mass index and colon cancer in a national sample of adult US men and women. , 1999, American journal of epidemiology.

[21]  J. Tuomilehto,et al.  Waist and hip circumferences, and waist-hip ratio in 19 populations of the WHO MONICA Project , 1999, International Journal of Obesity.

[22]  P. Björntorp,et al.  Secular increases in waist–hip ratio among Swedish women , 1998, International Journal of Obesity.

[23]  J. Seidell,et al.  Selection of anthropometric indicators for classification of abdominal fatness— a critical review , 1998, International Journal of Obesity.

[24]  M. Slattery,et al.  Body size and the risk of colon cancer in a large case-control study , 1998, International Journal of Obesity.

[25]  M. Gammon,et al.  Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia. , 1998, Journal of the National Cancer Institute.

[26]  Treatment of Obesity in Adults Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health. , 1998, Obesity research.

[27]  L. Kolonel,et al.  Diet, body size, physical activity, and the risk of endometrial cancer. , 1997, Cancer research.

[28]  Elio Riboli,et al.  The EPIC Project: Rationale and study design , 1997 .

[29]  E Riboli,et al.  The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition. , 1997, International journal of epidemiology.

[30]  C. Morrison,et al.  Waist circumference as a measure for indicating need for weight management , 1995, BMJ.

[31]  D Spiegelman,et al.  Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men. , 1995, American journal of epidemiology.

[32]  C. la Vecchia,et al.  Overweight and obesity in Italy, 1990-91. , 1994, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[33]  R. Gupta,et al.  Correlation of waist-hip ratio with coronary heart disease and risk factor prevalence in a rural male population. , 1994, Indian heart journal.

[34]  S. Sette,et al.  Nutritional status: anthropometry , 1991 .

[35]  T. Cole,et al.  Inter-observer variability in the measurement of body composition. , 1991, European journal of clinical nutrition.

[36]  J. Seidell,et al.  Fat distribution in European women: a comparison of anthropometric measurements in relation to cardiovascular risk factors. , 1990, International journal of epidemiology.

[37]  T. Lohman,et al.  Anthropometric Standardization Reference Manual , 1988 .

[38]  P. Björntorp,et al.  Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. , 1984, British medical journal.

[39]  A. Rimm,et al.  The association of girth measurements with disease in 32,856 women. , 1984, American journal of epidemiology.

[40]  C. Dolea,et al.  World Health Organization , 1949, International Organization.