Nanostructures in Hydrogen Peroxide Sensing

In recent years, several devices have been developed for the direct measurement of hydrogen peroxide (H2O2), a key compound in biological processes and an important chemical reagent in industrial applications. Classical enzymatic biosensors for H2O2 have been recently outclassed by electrochemical sensors that take advantage of material properties in the nano range. Electrodes with metal nanoparticles (NPs) such as Pt, Au, Pd and Ag have been widely used, often in combination with organic and inorganic molecules to improve the sensing capabilities. In this review, we present an overview of nanomaterials, molecules, polymers, and transduction methods used in the optimization of electrochemical sensors for H2O2 sensing. The different devices are compared on the basis of the sensitivity values, the limit of detection (LOD) and the linear range of application reported in the literature. The review aims to provide an overview of the advantages associated with different nanostructures to assess which one best suits a target application.

[1]  Chiyo Matsubara,et al.  Oxo[5, 10, 15, 20-tetra(4-pyridyl)porphyrinato]titanium(IV): an ultra-high sensitivity spectrophotometric reagent for hydrogen peroxide , 1992 .

[2]  S. K. Tiwari,et al.  Graphene research and their outputs: Status and prospect , 2020 .

[3]  Y. Ni,et al.  Electrochemical and bio-sensing platform based on a novel 3D Cu nano-flowers/layered MoS₂ composite. , 2016, Biosensors & bioelectronics.

[4]  L. Gorton,et al.  Sensor for Hydrogen Peroxide Based on Prussian Blue Modified Electrode: Improvement of the Operational Stability , 2000 .

[5]  A. Mills,et al.  Reversible, fluorescence-based optical sensor for hydrogen peroxide. , 2007, The Analyst.

[6]  H. Begum,et al.  A novel δ-MnO2 with carbon nanotubes nanocomposite as an enzyme-free sensor for hydrogen peroxide electrosensing , 2016 .

[7]  K. Ramamurthi,et al.  A new catalyst Ti doped CdO thin film for non-enzymatic hydrogen peroxide sensor application , 2019, Sensors and Actuators B: Chemical.

[8]  Jimena Claudia Lopez,et al.  Development of a third generation biosensor to determine hydrogen peroxide based on a composite of soybean peroxidase/chemically reduced graphene oxide deposited on glassy carbon electrodes , 2018 .

[9]  Metal-ion co-ordination assembly based multilayer of one dimensional gold nanostructures and catalase as electrochemical sensor for the analysis of hydrogen peroxide , 2017 .

[10]  J. Zen,et al.  A glucose biosensor employing a stable artificial peroxidase based on ruthenium purple anchored cinder. , 2003, Analytical chemistry.

[11]  Zhifeng Du,et al.  A novel nonenzymatic hydrogen peroxide sensor based on MnO2/graphene oxide nanocomposite. , 2010, Talanta.

[12]  A. Lambeir,et al.  Kinetics of the reaction of compound II of horseradish peroxidase with hydrogen peroxide to form compound III. , 1989, European journal of biochemistry.

[13]  Xuping Sun,et al.  Method for effective immobilization of Ag nanoparticles/graphene oxide composites on single-stranded DNA modified gold electrode for enzymeless H2O2 detection , 2011, Journal of Materials Science.

[14]  A. Malinauskas,et al.  Operational stability of amperometric hydrogen peroxide sensors, based on ferrous and copper hexacyanoferrates , 1999 .

[15]  Chi-Young Lee,et al.  Urchin-like Ag Nanowires as Non-enzymatic Hydrogen Peroxide Sensor , 2012 .

[16]  Gang Chen,et al.  Carbon-nanotube/copper composite electrodes for capillary electrophoresis microchip detection of carbohydrates. , 2004, The Analyst.

[17]  Zhiwei Zhu,et al.  Biosensor based on ultrasmall MoS2 nanoparticles for electrochemical detection of H2O2 released by cells at the nanomolar level. , 2013, Analytical chemistry.

[18]  Yan Wang,et al.  All Solid-State pH Electrode Based on Titanium Nitride Sensitive Film , 2006 .

[19]  A. Michael,et al.  Amperometric sensors for peroxide, choline, and acetylcholine based on electron transfer between horseradish peroxidase and a redox polymer. , 1993, Analytical chemistry.

[20]  Jenny Emnéus,et al.  Peroxidase-modified electrodes: Fundamentals and application , 1996 .

[21]  C. Strunk,et al.  Signal enhancement in amperometric peroxide detection by using graphene materials with low number of defects , 2015, Microchimica Acta.

[22]  A. Malinauskas,et al.  Evaluation of operational stability of Prussian blue- and cobalt hexacyanoferrate-based amperometric hydrogen peroxide sensors for biosensing application , 2004 .

[23]  Yan Shi,et al.  Facile synthesis of Prussian blue @ gold nanocomposite for nonenzymatic detection of hydrogen peroxide , 2013 .

[24]  Lijuan Han,et al.  Prussian blue @ platinum nanoparticles/graphite felt nanocomposite electrodes: application as hydrogen peroxide sensor. , 2013, Biosensors & bioelectronics.

[25]  John Bosco Balaguru Rayappan,et al.  Nanostructured ZnO thin film for hydrogen peroxide sensing , 2011 .

[26]  Oh Seok Kwon,et al.  Cytochrome C-decorated graphene field-effect transistor for highly sensitive hydrogen peroxide detection , 2020 .

[27]  Sudip Chakraborty,et al.  Pt nanoparticle-based highly sensitive platform for the enzyme-free amperometric sensing of H2O2. , 2009, Biosensors & bioelectronics.

[28]  Guangchao Zhao,et al.  Direct electrocatalytic oxidation of nitric oxide and reduction of hydrogen peroxide based on alpha-Fe2O3 nanoparticles-chitosan composite. , 2010, Talanta.

[29]  Lo Gorton,et al.  On the mechanism of H2O2 reduction at Prussian Blue modified electrodes , 1999 .

[30]  T Laurell,et al.  Development of biosensors based on hexacyanoferrates. , 2000, Talanta.

[31]  Zhe Zhang,et al.  A hydrogen peroxide sensor based on Ag nanoparticles electrodeposited on natural nano-structure attapulgite modified glassy carbon electrode. , 2011, Talanta.

[32]  Roya Maboudian,et al.  Palladium nanostructures from galvanic displacement as hydrogen peroxide sensor , 2010 .

[33]  S. Bourbigot,et al.  Water-assisted extrusion as a novel processing route to prepare polypropylene/halloysite nanotube nanocomposites: Structure and properties , 2011 .

[34]  Theyagarajan K,et al.  Electrochemical biosensor for the detection of hydrogen peroxide using cytochrome c covalently immobilized on carboxyl functionalized ionic liquid/multiwalled carbon nanotube hybrid , 2019, Applied Surface Science.

[35]  Hongsheng Tang,et al.  Electrodeposition of Prussian blue nanoparticles on polyaniline coated halloysite nanotubes for nonenzymatic hydrogen peroxide sensing , 2015 .

[36]  F. Zhao,et al.  Direct electrochemistry of horseradish peroxidase in gelatin-hydrophobic ionic liquid gel films , 2007 .

[37]  Aldo J. G. Zarbin,et al.  A Simple and Innovative Route to Prepare a Novel Carbon Nanotube/Prussian Blue Electrode and its Utilization as a Highly Sensitive H2O2 Amperometric Sensor , 2009 .

[38]  M. Najam-ul-Haq,et al.  Catalase immobilized antimonene quantum dots used as an electrochemical biosensor for quantitative determination of H2O2 from CA-125 diagnosed ovarian cancer samples. , 2020, Materials science & engineering. C, Materials for biological applications.

[39]  Sujuan Li.  A Novel Enzyme-Free Hydrogen Peroxide Sensor Based on Electrode Modified with Gold Nanoparticles-Overoxidized Polydopamine Composites , 2016, International Journal of Electrochemical Science.

[40]  Wei Chen,et al.  Non-enzymatic hydrogen peroxide electrochemical sensor based on a three-dimensional MnO2 nanosheets/carbon foam composite , 2014 .

[41]  F. Ricci,et al.  Investigation of the effect of different glassy carbon materials on the performance of Prussian blue based sensors for hydrogen peroxide , 2003 .

[42]  Chengzhou Zhu,et al.  Electrochemical Sensors and Biosensors Based on Nanomaterials and Nanostructures , 2014, Analytical chemistry.

[43]  Audrey Sassolas,et al.  Immobilization strategies to develop enzymatic biosensors. , 2012, Biotechnology advances.

[44]  F. Marken,et al.  Directed assembly of multilayers--the case of Prussian blue. , 2001, Chemical communications.

[45]  N. Hu,et al.  Direct electrochemistry and electrocatalysis with horseradish peroxidase in Eastman AQ films. , 2001, Bioelectrochemistry.

[46]  Jian Fang,et al.  Amperometric detection of hydrogen peroxide utilizing synergistic action of cobalt hexacyanoferrate and carbon nanotubes chemically modified with platinum nanoparticles , 2013 .

[47]  Tsung-Hsuan Tsai,et al.  Performing enzyme-free H2O2 biosensor and simultaneous determination for AA, DA, and UA by MWCNT-PEDOT film. , 2010, Biosensors & bioelectronics.

[48]  Euna Ko,et al.  Fabrication of flexible, transparent silver nanowire electrodes for amperometric detection of hydrogen peroxide , 2016 .

[49]  Annamalai Senthil Kumar,et al.  An iron impurity in multiwalled carbon nanotube complexes with chitosan that biomimics the heme-peroxidase function. , 2013, Chemistry.

[50]  Shen-ming Chen,et al.  Poly (Toluidine Blue) and Zirconia Nanoparticles Electrochemically Deposited at Gelatin-Multiwalled Carbon Nanotube Film for Amperometric H2O2 Sensor , 2011, International Journal of Electrochemical Science.

[51]  Ning Li,et al.  Nanomaterial-based biosensors using dual transducing elements for solution phase detection. , 2015, The Analyst.

[52]  Xiangheng Niu,et al.  Doping ionic liquid into Prussian blue-multiwalled carbon nanotubes modified screen-printed electrode to enhance the nonenzymatic H2O2 sensing performance , 2014 .

[53]  Yidan Wang,et al.  Nanostructured biosensors built with layer-by-layer electrostatic assembly of hemoglobin and Fe₃O₄@Pt nanoparticles. , 2013, Colloids and surfaces. B, Biointerfaces.

[54]  D. Armbruster,et al.  Limit of blank, limit of detection and limit of quantitation. , 2008, The Clinical biochemist. Reviews.

[55]  P. Pandey,et al.  Carbon nanotubes: Types, methods of preparation and applications , 2016 .

[56]  Yimin Zhu,et al.  A novel self-powered bioelectrochemical sensor based on CoMn2O4 nanoparticle modified cathode for sensitive and rapid detection of hydrogen peroxide , 2018, Sensors and Actuators B: Chemical.

[57]  K. R. Seddon,et al.  Ionic Liquids Completely UnCOILed: Critical Expert Overviews , 2015 .

[58]  E. C. Hurdis,et al.  Accuracy of Determination of Hydrogen Peroxide by Cerate Oxidimetry , 1954 .

[59]  C. Brett,et al.  Enzyme immobilisation on electroactive nanostructured membranes (ENM): optimised architectures for biosensing. , 2008, Talanta.

[60]  Wei Zhang,et al.  Low‐Potential Sensitive Hydrogen Peroxide Detection Based on Nanotubular TiO2 and Platinum Composite Electrode , 2008 .

[61]  E. McAdams,et al.  Nickel hexacyanoferrate modified screen-printed carbon electrode for sensitive detection of ascorbic acid and hydrogen peroxide. , 2005, Frontiers in bioscience : a journal and virtual library.

[62]  J. Shan,et al.  Atomically thin MoS₂: a new direct-gap semiconductor. , 2010, Physical review letters.

[63]  A. Guiseppi-Elie,et al.  Microfabricated biosensor for the simultaneous amperometric and luminescence detection and monitoring of Ochratoxin A. , 2016, Biosensors & bioelectronics.

[64]  Nina Dimcheva.  Nanostructures of noble metals as functional materials in biosensors , 2020 .

[65]  Nannan Zheng,et al.  Interconnected 1D Co3O4 nanowires on reduced graphene oxide for enzymeless H2O2 detection , 2015, Nano Research.

[66]  Lixia Yang,et al.  An electro-catalytic biosensor fabricated with Pt-Au nanoparticle-decorated titania nanotube array. , 2008, Bioelectrochemistry.

[67]  Lauro T. Kubota,et al.  Direct electron transfer: an approach for electrochemical biosensors with higher selectivity and sensitivity , 2003 .

[68]  Jianshan Ye,et al.  Bifunctional and highly sensitive electrochemical non-enzymatic glucose and hydrogen peroxide biosensor based on NiCo2O4 nanoflowers decorated 3D nitrogen doped holey graphene hydrogel. , 2019, Materials science & engineering. C, Materials for biological applications.

[69]  Q. Gao,et al.  A novel photoelectrochemical hydrogen peroxide sensor based on nickel(II)-potassium hexacyanoferrate-graphene hybrid materials modified n-silicon electrode , 2016, Journal of Solid State Electrochemistry.

[70]  M. Terrones,et al.  Two-dimensional and three-dimensional hybrid assemblies based on graphene oxide and other layered structures: A carbon science perspective , 2017 .

[71]  J. Mintmire,et al.  ELECTRONIC AND STRUCTURAL PROPERTIES OF CARBON NANOTUBES , 1996 .

[72]  Yogeswaran Umasankar,et al.  A Review on Direct Electrochemistry of Catalase for Electrochemical Sensors , 2009, Sensors.

[73]  Wanzhi. Wei,et al.  Fabrication of a copper nanoparticle/chitosan/carbon nanotube-modified glassy carbon electrode for electrochemical sensing of hydrogen peroxide and glucose , 2008 .

[74]  Szabolcs János Györfi,et al.  Detection of hydrogen peroxide involving bismuth nanowires via template-free electrochemical synthesis using deep eutectic solvents , 2020 .

[75]  Zhengcao Li,et al.  Fabrication of TiN nanostructure as a hydrogen peroxide sensor by oblique angle deposition , 2014, Nanoscale Research Letters.

[76]  Lin Gu,et al.  A biocompatible titanium nitride nanorods derived nanostructured electrode for biosensing and bioelectrochemical energy conversion. , 2011, Biosensors & bioelectronics.

[77]  E. Gucciardi,et al.  Lubricants: properties and characteristics. , 2013 .

[78]  L. Gorton,et al.  Highly sensitive, stable and selective hydrogen peroxide amperometric biosensors based on peroxidases from different sources wired by Os-polymer: A comparative study , 2018 .

[79]  Lei Wang,et al.  Chemiluminescence flow biosensor for hydrogen peroxide using DNAzyme immobilized on eggshell membrane as a thermally stable biocatalyst. , 2009, Biosensors & bioelectronics.

[80]  K. Imai,et al.  High-Performance Liquid Chromatographic Determination of Hydrogen Peroxide with Peroxyoxalate Chemiluminescence Detection , 1994 .

[81]  A. Karyakin,et al.  Prussian Blue-Based First-Generation Biosensor. A Sensitive Amperometric Electrode for Glucose , 1995 .

[82]  Saleh A. Al-Sayari,et al.  Fabrication of non-enzymatic sensor using Co doped ZnO nanoparticles as a marker of H2O2 , 2014 .

[83]  R. Inguanta,et al.  A nanostructured sensor of hydrogen peroxide , 2017 .

[84]  Danila Moscone,et al.  Development of a Hydrogen Peroxide Sensor Based on Screen-Printed Electrodes Modified with Inkjet-Printed Prussian Blue Nanoparticles , 2014, Sensors.

[85]  C. Sow,et al.  CoOOH nanosheet electrodes: Simple fabrication for sensitive electrochemical sensing of hydrogen peroxide and hydrazine. , 2013, Biosensors & bioelectronics.

[86]  Li Zhang,et al.  Facile synthesis of flower like copper oxide and their application to hydrogen peroxide and nitrite sensing , 2011, Chemistry Central journal.

[87]  M. Shokouhimehr.  Prussian Blue Nanoparticles and its Analogues as New-Generation T1-Weighted MRI Contrast Agents for Cellular Imaging , 2010 .

[88]  Xiaojun Zhang,et al.  Amperometric Detection of Hydrogen Peroxide Using Glassy Carbon Electrodes Modified with Chromium Hexacyanoferrate/Single‐Walled Carbon Nanotube Nanocomposites , 2009 .

[89]  Chun‐Hu Chen,et al.  Redox preparation of mixed-valence cobalt manganese oxide nanostructured materials: highly efficient noble metal-free electrocatalysts for sensing hydrogen peroxide. , 2014, Nanoscale.

[90]  S. Mori,et al.  Manganese oxides/carbon nanowall nanocomposite electrode as an efficient non-enzymatic electrochemical sensor for hydrogen peroxide , 2020 .

[91]  Youngkwan Lee,et al.  Hydrogen peroxide detection using a polypyrrole/Prussian blue nanowire modified electrode , 2011 .

[92]  Yunyun Zhai,et al.  Prussian Blue/Reduced Graphene Oxide Composite for the Amperometric Determination of Dopamine and Hydrogen Peroxide , 2015 .

[93]  G. Ostojic,et al.  Carbon Nanotubes , 2010, Methods in Molecular Biology.

[94]  L. Gorton,et al.  Prussian-Blue-based amperometric biosensors in flow-injection analysis. , 1996, Talanta.

[95]  Constantin Mihailciuc,et al.  Screen-printed Prussian Blue modified electrode for simultaneous detection of hydroquinone and catechol , 2014 .

[96]  Kaiming Liao,et al.  Porous cuprous oxide microcubes for non-enzymatic amperometric hydrogen peroxide and glucose sensing , 2009 .

[97]  Junhong Zhao,et al.  A novel nonenzymatic H2O2 sensor based on cobalt hexacyanoferrate nanoparticles and graphene composite modified electrode , 2015 .

[98]  G. Muralidharan,et al.  Amperometric sensing of hydrogen peroxide using glassy carbon electrode modified with copper nanoparticles , 2015 .

[99]  M. Iwaniec,et al.  A comparative study of electrocatalytic reduction of hydrogen peroxide at carbon rod electrodes decorated with silver particles , 2021 .

[100]  Dan Xiao,et al.  H2O2 sensor based on the room-temperature phosphorescence of Nano TiO2/SiO2 composite. , 2007, Analytical chemistry.

[101]  C. Liu,et al.  Improvement of Amperometric Biosensor Performance for H2O2 Detection based on Bimetallic PtM (M = Ru, Au, and Ir) Nanoparticles , 2012 .

[102]  S. Pandey,et al.  Applications of Ionic Liquids in Spectroscopy , 2013 .

[103]  A. Ahammad.  Hydrogen Peroxide Biosensors Based on Horseradish Peroxidase and Hemoglobin , 2012 .

[104]  Fenghua Li,et al.  Polyethyleneimine-functionalized graphene and its layer-by-layer assembly with Prussian blue , 2013 .

[105]  E. F. Treo,et al.  Evaluation of chrono-impedance technique as transduction method for a carbon paste/glucose oxidase (CP/GOx) based glucose biosensor. , 2010, Biosensors & bioelectronics.

[106]  Q. Bui,et al.  A novel nanohybrid of cobalt oxide-sulfide nanosheets deposited three-dimensional foam as efficient sensor for hydrogen peroxide detection , 2020 .

[107]  O. Crosby,et al.  nanotubes , 2020, Catalysis from A to Z.

[108]  J. Luong,et al.  Electrochemical biosensing platforms using platinum nanoparticles and carbon nanotubes. , 2004, Analytical chemistry.