Population pharmacokinetic modelling of carbamazepine in epileptic elderly patients: implications for dosage

Background:  Proper use of antiepileptic drugs in the elderly involves knowledge of their pharmacokinetics to ensure a patient‐specific balance between efficacy and toxicity. However, populations of epileptic patients on chronic carbamazepine (CBZ) therapy which have been studied have included data of relatively few elderly patients.

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