Disseminated Cryptococcus treated with transfer factor.

Cardiac toxic reactions and pulmonary consolidation in the left lower lobe developed in a patient who was receiving amphotericin B therapy for cryptococcal meningitis. Following surgical resection of the lobe, multiple subcutaneous cryptococcal abscesses appeared. Flucytosine administered intravenously failed to eradicate the lesions. Transfer factor therapy and multiple drainage procedures elimniated the skin abscesses. Transfer factor therapy was administered for one year; the patient was asymptomatic 16 months after therapy was discontinued.

[1]  E. Harder,et al.  Treatment of fungal infections with flucytosine. , 1975, Archives of internal medicine.

[2]  S. Balcerzak,et al.  Immunologic specificity of transfer factor. , 1974, The Journal of clinical investigation.

[3]  M. Just,et al.  CIRCULATING INTERFERON AFTER TRANSFER-FACTOR THERAPY , 1973 .

[4]  R. Snyderman,et al.  Defective mononuclear leukocyte chemotaxis: a previously unrecognized immune dysfunction. Studies in a patient with chronic mucocutaneous candidiasis. , 1973, Annals of internal medicine.

[5]  R. Eisenberg,et al.  Nebulization of amphotericin B. , 1971, The American review of respiratory disease.

[6]  J. Bates,et al.  Amphotericin B toxicity. A follow-up report of 53 patients. , 1969, Annals of internal medicine.

[7]  L. Spitler,et al.  Transfer factor II: results of therapy. , 1975, Birth defects original article series.

[8]  Lawrence Hs Transfer factor in cellular immunity. , 1974 .