Cardiorespiratory Fitness as a Predictor of Successful Cognitive Ageing

This study examined whether cardiorespiratory fitness influences cognitive ageing and whether this influence is domain specific. A cross-sectional design comprising 25 young (18–30 years), 25 young-old (65–74 years), 25 middle-old (75–84 years) and 25 old-old adults (85–92 years) compared the relationship between cardiorespiratory fitness (VO2max) and measures of processing resources (attention, working memory, speed) and higher-order cognitive functions (executive function, memory). Fitness was a strong predictor of cognition and accounted for more variance in processing resources than in higher-order functions. This suggests that cardiorespiratory fitness may have a selective protective effect against age-associated cognitive decline. We gratefully acknowledge the participation of all of the men and women who volunteered for this study. This research was funded by a RM Gibson Scientific Research Fund grant from the Australian Association of Gerontology.

[1]  B. Milner,et al.  Interhemispheric differences in the localization of psychological processes in man. , 1971, British medical bulletin.

[2]  S. Hofer,et al.  Evaluating the interdependence of aging-related changes in visual and auditory acuity, balance, and cognitive functioning. , 2003, Psychology and aging.

[3]  H. Christensen,et al.  Use It and Still Lose It? The Association Between Activity and Cognitive Performance Established Using Latent Growth Techniques in a Community Sample , 2003 .

[4]  E. McAuley,et al.  Influence of aerobic fitness on the neurocognitive function of older adults , 2000 .

[5]  E. Kemps,et al.  Patterns and Predictors of Adult Age Differences in Mental Imagery , 2005 .

[6]  P. Wong,et al.  Psychological and Physical Well-Being in the Elderly: The Perceived Well-Being Scale (PWB) , 1984, Canadian Journal on Aging / La Revue canadienne du vieillissement.

[7]  K. Anstey,et al.  Test-Retest Reliability of a Battery of Sensory, Motor and Physiological Measures of Aging , 1997, Perceptual and motor skills.

[8]  Seymour Sudman,et al.  Cognition, aging, and self-reports , 1999 .

[9]  Arthur F. Kramer,et al.  Neurocognitive aging and cardiovascular fitness , 2007, Journal of Molecular Neuroscience.

[10]  W. Greenough,et al.  Environment and the aging brain. , 1987, Canadian journal of psychology.

[11]  W. Spirduso,et al.  Physical fitness, aging, and psychomotor speed: a review. , 1980, Journal of gerontology.

[12]  J. J. Ryan,et al.  Wechsler Adult Intelligence Scale-III , 2001 .

[13]  L. Burkett,et al.  Non-exercise VO2max estimation for physically active college students. , 1997, Medicine and science in sports and exercise.

[14]  J. Etnier,et al.  Components of Response Time as a Function of Age, Physical Activity, and Aerobic Fitness , 2003 .

[15]  A HENSCHEL,et al.  Maximal oxygen intake as an objective measure of cardio-respiratory performance. , 1955, Journal of applied physiology.

[16]  M. Trabucchi,et al.  Physical activity and cognitive decline in elderly persons. , 2002, Archives of internal medicine.

[17]  J. Jolles,et al.  Self-reported physical activity, subjective health, and cognitive performance in older adults. , 1996, Experimental aging research.

[18]  O. Spreen,et al.  Predicting premorbid IQ: A revision of the national adult reading test , 1989 .

[19]  R. L. Rogers,et al.  After Reaching Retirement Age Physical Activity Sustains Cerebral Perfusion and Cognition , 1990, Journal of the American Geriatrics Society.

[20]  J. Stroop Studies of interference in serial verbal reactions. , 1992 .

[21]  D. Roth,et al.  Association between aerobic fitness and visuospatial performance in healthy older adults. , 1992, Psychology and aging.

[22]  L P Lipsitt,et al.  Life-span developmental psychology. , 1980, Annual review of psychology.

[23]  Ellen Woo,et al.  COGNITIVE AGING AND PHYSICAL EXERCISE , 2003 .

[24]  T. Salthouse,et al.  Interrelations of age, health, and speed. , 1995, The journals of gerontology. Series B, Psychological sciences and social sciences.

[25]  E. Kemps,et al.  General lifestyle activities as a predictor of current cognition and cognitive change in older adults: a cross-sectional and longitudinal examination. , 2005, The journals of gerontology. Series B, Psychological sciences and social sciences.

[26]  H. Williford,et al.  Cross-validation of non-exercise predictions of VO2peak in women. , 1996, Medicine and science in sports and exercise.

[27]  K. Yaffe,et al.  A Longitudinal Study of Cardiorespiratory Fitness and Cognitive Function in Healthy Older Adults , 2003, Journal of the American Geriatrics Society.

[28]  U. Staudinger,et al.  Life Span Theory in Developmental Psychology , 2007 .

[29]  M. Visser,et al.  Early Life Physical Activity and Cognition at Old Age , 2003, Journal of clinical and experimental neuropsychology.

[30]  P. Baltes,et al.  Emergence of a Powerful Connection Between Sensory and Cognitive Functions Across the Adult Life Span: A New Window to the Study of Cognitive Aging? , 1997 .

[31]  Michael E. Miller,et al.  Exercise and depressive symptoms: a comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology. , 2002, The journals of gerontology. Series B, Psychological sciences and social sciences.

[32]  Waneen Wyrick Spirduso,et al.  Physical dimensions of aging , 1995 .

[33]  J. Mitchell,et al.  The physiological meaning of the maximal oxygen intake test. , 1958, The Journal of clinical investigation.

[34]  Eva Kemps,et al.  Comparison of Adult Age Differences in Verbal and Visuo-Spatial Memory: The Importance of ‘Pure’, Parallel and Validated Measures , 2006, Journal of clinical and experimental neuropsychology.

[35]  A S Jackson,et al.  Prediction of functional aerobic capacity without exercise testing. , 1990, Medicine and science in sports and exercise.

[36]  David J. Madden,et al.  Effects of Exercise Training on Cognitive Functioning among Depressed Older Men and Women , 2001 .

[37]  W. Spirduso,et al.  Systematic aerobic exercise and components of reaction time in older women. , 1988, Journal of gerontology.

[38]  Eva Bertha Kemps,et al.  Cognitive Mechanisms Underlying Decrements in Mental Synthesis in Older Adults , 2003 .

[39]  D. Hultsch,et al.  Age differences in cognitive performance in later life: relationships to self-reported health and activity life style. , 1993, Journal of gerontology.

[40]  Joep C. Teeken,et al.  Aerobic capacity and cognitive performance in a cross-sectional aging study. , 1997, Medicine and science in sports and exercise.

[41]  D. Edwards,et al.  Effects of a three-year exercise program on motor function and cognitive processing speed in older women. , 1991, Research quarterly for exercise and sport.

[42]  N. R. Ellis,et al.  The Influence of Physical Fitness on Automatic and Effortful Memory Changes in Aging , 1992, International journal of aging & human development.

[43]  J. Jolles,et al.  EDUCATION AND AGE-RELATED COGNITIVE DECLINE: THE CONTRIBUTION OF MENTAL WORKLOAD , 2003 .

[44]  Jacob Cohen,et al.  Applied multiple regression/correlation analysis for the behavioral sciences , 1979 .

[45]  D. Royall,et al.  CLOX: an executive clock drawing task , 1998, Journal of neurology, neurosurgery, and psychiatry.

[46]  P. Baltes,et al.  Intellectual functioning in old and very old age: cross-sectional results from the Berlin Aging Study. , 1997, Psychology and aging.

[47]  B. Tabachnick,et al.  Using Multivariate Statistics , 1983 .

[48]  Perceived Exertion during Physical Exercise among Individuals High and Low in Fitness , 1996, Perceptual and motor skills.

[49]  T. Salthouse The processing-speed theory of adult age differences in cognition. , 1996, Psychological review.

[50]  K J Anstey,et al.  Interrelationships among biological markers of aging, health, activity, acculturation, and cognitive performance in late adulthood. , 1999, Psychology and aging.