Electrically evoked myoelectric signals.

Electrical stimulation of the nervous system is attracting increasing attention because of the possibilities it offers for physiological investigations, clinical diagnosis, muscle function assessment, noninvasive muscle characterization, and functional control of paralyzed extremities. Parameters of the myoelectric signal evoked by surface stimulation of a muscle motor point or by stimulation of a nerve trunk by means of implanted electrodes provide information about muscle performance and properties if the stimulation artifact is properly removed or suppressed. Comparison of these parameters with those obtained during voluntary contractions provides additional insight into muscle physiology. The relationships between myoelectric signal amplitude parameters, spectral parameters, and conduction velocity are discussed with special reference to muscle fatigue. This review focuses on a few methodological aspects concerning electrical stimulation of the peripheral nervous system, detection, and processing of the electrically evoked myoelectric signals in skeletal muscles. The state of the art of the following issues is discussed: (1) properties of voluntary and electrically evoked myoelectric signals; (2) techniques for evoking and detecting myoelectric signals; (3) techniques for suppression of stimulation artifacts; (4) effect of stimulation waveforms and electrode properties; (5) signal processing techniques for electrically evoked myoelectric signals; (6) physiological significance of myoelectric signal variables; (7) order of recruitment of motor units during electrical stimulation; (8) myoelectric manifestations of fatigue in electrically stimulated muscles; (9) assessment of crosstalk by electrical stimulation; and (10) applications in sport, rehabilitation, and geriatric medicine.

[1]  F BUCHTHAL,et al.  Innervation zone and propagation velocity in human muscle. , 1955, Acta physiologica Scandinavica.

[2]  F BUCHTHAL,et al.  Propagation velocity in electrically activated muscle fibres in man. , 1955, Acta physiologica Scandinavica.

[3]  C. Håkansson.  Conduction velocity and amplitude of the action potential as related to circumference in the isolated fibre of frog muscle. , 1956, Acta physiologica Scandinavica.

[4]  Force, Pain and Electrode Size in the Electrical Stimulation of Leg Muscles , 1969, Nature.

[5]  M J Campbell,et al.  Electrophysiological estimation of the number of motor units within a human muscle , 1971, Journal of neurology, neurosurgery, and psychiatry.

[6]  J. A. Freeman.  An electronic stimulus artifact suppressor. , 1971, Electroencephalography and Clinical Neurophysiology.

[7]  H. Elden,et al.  Biophysical properties of the skin , 1971 .

[8]  L. Geddes.  Electrodes and the measurement of bioelectric events , 1972 .

[9]  Numbers and Sizes of Human Motor Units in Health and Disease , 1973 .

[10]  R. H. Adrian,et al.  Reconstruction of the action potential of frog sartorius muscle , 1973, The Journal of physiology.

[11]  J Hanson,et al.  The effects of repetitive stimulation on the action potential and the twitch of rat muscle. , 1974, Acta physiologica Scandinavica.

[12]  Influence of various factors on the length of the summated depolarized area of the muscle fibres in voluntary activating of motor units and electrical stimulation. , 1974, Electromyography and clinical neurophysiology.

[13]  R J Roby,et al.  A simplified circuit for stimulus artifact suppression. , 1975, Electroencephalography and clinical neurophysiology.

[14]  A. Trnkoczy,et al.  Optimal stimulus parameters for minimum pain in the chronic stimulation of innervated muscle. , 1975, Archives of physical medicine and rehabilitation.

[15]  N. Mackay,et al.  Pain Sensations Associated with Electrocutaneous Stimulation , 1976, IEEE Transactions on Biomedical Engineering.

[16]  C. Marsden,et al.  Proceedings: Fatigue in human muscle in relation to the number and frequency of motor impulses. , 1976, The Journal of physiology.

[17]  Kenneth R. Brennen.  The Characterization of Transcutaneous Stimulating Electrodes , 1976, IEEE Transactions on Biomedical Engineering.

[18]  L.H. Lindstrom,et al.  Interpretation of myoelectric power spectra: A model and its applications , 1977, Proceedings of the IEEE.

[19]  N. Accornero,et al.  Selective Activation of peripheral nerve fibre groups of different diameter by triangular shaped stimulus pulses. , 1977, The Journal of physiology.

[20]  T L Babb,et al.  A sample and hold amplifier system for stimulus artifact suppression. , 1978, Electroencephalography and clinical neurophysiology.

[21]  D. D. Walker,et al.  A fast-recovery electrode amplifier for electrophysiology. , 1978, Electroencephalography and clinical neurophysiology.

[22]  J. J. Woods,et al.  Excitation frequency and muscle fatigue: Electrical responses during human voluntary and stimulated contractions , 1979, Experimental Neurology.

[23]  D. Lampard,et al.  Derivation of reliable electromyograms and their relation to tension in mammalian skeletal muscles during synchronous stimulation. , 1979, Electroencephalography and clinical neurophysiology.

[24]  Bruno O. Shubert,et al.  Random variables and stochastic processes , 1979 .

[25]  R. Gruener,et al.  Conduction velocities in single fibers of diseased human muscle , 1979, Neurology.

[26]  B. Bigland-ritchie,et al.  Excitation frequency and muscle fatigue: Mechanical responses during voluntary and stimulated contractions , 1979, Experimental Neurology.

[27]  Smith Mb,et al.  Electrode effectiveness during transcutaneous motor stimulation. , 1980 .

[28]  R L Waters,et al.  Electrode effectiveness during transcutaneous motor stimulation. , 1980, Archives of physical medicine and rehabilitation.

[29]  D. Antonelli,et al.  Surface versus intramuscular electrodes for electromyography of superficial and deep muscles. , 1981, Physical therapy.

[30]  B. Bigland-ritchie.  EMG and fatigue of human voluntary and stimulated contractions. , 2008, Ciba Foundation symposium.

[31]  J. Rinzel,et al.  The dependence of impulse propagation speed on firing frequency, dispersion, for the Hodgkin-Huxley model. , 1981, Biophysical journal.

[32]  C. D. De Luca,et al.  Frequency Parameters of the Myoelectric Signal as a Measure of Muscle Conduction Velocity , 1981, IEEE Transactions on Biomedical Engineering.

[33]  D. Jones,et al.  Muscle fatigue due to changes beyond the neuromuscular junction. , 1981, Ciba Foundation symposium.

[34]  Merton Pa,et al.  Indirect and direct stimulation of fatigued human muscle. , 2008, Ciba Foundation symposium.

[35]  J. Daube,et al.  Muscles Alive , 1981, Neurology.

[36]  H J Spencer.  An automatic, optically isolated, biphasic constant current stimulator adapter for artefact suppression. , 1981, Electroencephalography and clinical neurophysiology.

[37]  D. M. Lewis,et al.  The Physiology of Motor Units in Mammalian Skeletal Muscle , 1981 .

[38]  G. Gottlieb,et al.  Reciprocal excitation of antagonistic muscles as a differentiating feature in spasticity , 1982, Annals of neurology.

[39]  Tadashi Masuda,et al.  The Measurement of Muscle Fiber Conduction Velocity Using a Gradient Threshold Zero-Crossing Method , 1982, IEEE Transactions on Biomedical Engineering.

[40]  Volume conduction of motor unit potentials from different human muscles to long distances. , 1982, Electromyography and clinical neurophysiology.

[41]  D Hary,et al.  A statistical analysis of the spectral moments used in EMG tests of endurance. , 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

[42]  E Eldred,et al.  Fatigue considerations of muscle contractile force during high-frequency stimulation. , 1983, American journal of physical medicine.

[43]  C. D. De Luca,et al.  Myoelectric signal versus force relationship in different human muscles. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

[44]  G F Inbar,et al.  Optimization of pulse duration and pulse charge during transcutaneous electrical nerve stimulation. , 1983, The Australian journal of physiotherapy.

[45]  R. Silberstein,et al.  Factors determining the frequency content of the electromyogram. , 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

[46]  M Naeije,et al.  Estimation of the action potential conduction velocity in human skeletal muscle using the surface EMG cross-correlation technique. , 1983, Electromyography and clinical neurophysiology.

[47]  H. Sjöholm,et al.  Electromyogram, force and relaxation time during and after continuous electrical stimulation of human skeletal muscle in situ. , 1983, The Journal of physiology.

[48]  J. Mortimer,et al.  The Effect of Stimulus Parameters on the Recruitment Characteristics of Direct Nerve Stimulation , 1983, IEEE Transactions on Biomedical Engineering.

[49]  C. J. Luca.  Myoelectrical manifestations of localized muscular fatigue in humans. , 1984 .

[50]  P. Hilfiker,et al.  Normal and myopathic propagation of surface motor unit action potentials. , 1984, Electroencephalography and clinical neurophysiology.

[51]  D Kosarov,et al.  Estimation of the spreading velocity and the parameters of the muscle potentials by averaging of the summated electromyogram. , 1984, Electromyography and clinical neurophysiology.

[52]  K. Hainaut,et al.  Electrical and mechanical failures during sustained and intermittent contractions in humans. , 1985, Journal of applied physiology.

[53]  T. Moritani,et al.  Electromechanical changes during electrically induced and maximal voluntary contractions: Electrophysiologic responses of different muscle fiber types during stimulated contractions , 1985, Experimental Neurology.

[54]  F. A. Gaffney,et al.  Electromechanical changes during electrically induced and maximal voluntary contractions: Surface and intramuscular EMG responses during sustained maximal voluntary contraction , 1985, Experimental Neurology.

[55]  N. Battistini,et al.  Automatic analysis of surface EMG (preliminary findings in healthy subjects and in patients with neurogenic motor diseases). , 1985, Electroencephalography and clinical neurophysiology.

[56]  John G. Proakis,et al.  Probability, random variables and stochastic processes , 1985, IEEE Trans. Acoust. Speech Signal Process..

[57]  R. D'ambrosia,et al.  A technique for recording the EMG of electrically stimulated skeletal muscle. , 1985, Orthopedics.

[58]  G. Alon.  High voltage stimulation. Effects of electrode size on basic excitatory responses. , 1985, Physical therapy.

[59]  J. Fridén,et al.  Distribution of fibre sizes in human skeletal muscle. An enzyme histochemical study in m tibialis anterior. , 1985, Acta physiologica Scandinavica.

[60]  L. Arendt-Nielsen,et al.  The relationship between mean power frequency of the EMG spectrum and muscle fibre conduction velocity. , 1985, Electroencephalography and clinical neurophysiology.

[61]  Carlo J. De Luca,et al.  A Note on the Noninvasive Estimation of Muscle Fiber Conduction Velocity , 1985, IEEE Transactions on Biomedical Engineering.

[62]  F E Zajac,et al.  Relationship among recruitment order, axonal conduction velocity, and muscle-unit properties of type-identified motor units in cat plantaris muscle. , 1985, Journal of neurophysiology.

[63]  C. D. De Luca,et al.  Myoelectric signal conduction velocity and spectral parameters: influence of force and time. , 1985, Journal of applied physiology.

[64]  G. Zilvold,et al.  The measurement of the conduction velocity of muscle fibres with surface EMG according to the cross-correlation method. , 1985, Electromyography and clinical neurophysiology.

[65]  J. Albers,et al.  Single motor unit and fiber action potentials during fatigue. , 1985, Journal of applied physiology.

[66]  C. D. De Luca,et al.  Effects of electrode location on myoelectric conduction velocity and median frequency estimates. , 1986, Journal of applied physiology.

[67]  H. Milner-Brown,et al.  Muscle membrane excitation and impulse propagation velocity are reduced during muscle fatigue , 1986, Muscle & nerve.

[68]  R. D'ambrosia,et al.  The Myoelectric Signal of Electrically Stimulated Muscle During Recruitment: An Inherent Feedback Pareter for a Closed-Loop Control Scheme , 1986, IEEE Transactions on Biomedical Engineering.

[69]  D. Mcneal,et al.  Response of single alpha motoneurons to high-frequency pulse trains. Firing behavior and conduction block phenomenon. , 1986, Applied neurophysiology.

[70]  K. Singer.  The influence of unilateral electrical muscle stimulation on motor unit activity patterns in atrophic human quadriceps. , 1986, The Australian journal of physiotherapy.

[71]  G. Strauss,et al.  A review of the use of electro-motor stimulation in human muscles. , 1986, The Australian journal of physiotherapy.

[72]  Fatigue Response in Human Quadriceps Femoris Muscle during High Frequency Electrical Stimulation*. , 1986, The Journal of orthopaedic and sports physical therapy.

[73]  R. D'ambrosia,et al.  The EMG-Force Model of Electrically Stimulated Muscle: Dependence on Control Strategy and Predominant Fiber Composition , 1987, IEEE Transactions on Biomedical Engineering.

[74]  B. Bigland-ritchie,et al.  Central components of diaphragmatic fatigue assessed by phrenic nerve stimulation. , 1987, Journal of applied physiology.

[75]  Davies Sw,et al.  Estimation of myoelectric conduction velocity distribution. , 1987 .

[76]  Jiri Silny,et al.  Spatial Filtering of Noninvasive Multielectrode EMG: Part II-Filter Performance in Theory and Modeling , 1987, IEEE Transactions on Biomedical Engineering.

[77]  Moshe Solomonow,et al.  Manipulation of Muscle Force with Various Firing Rate and Recruitment Control Strategies , 1987, IEEE Transactions on Biomedical Engineering.

[78]  Dimitrov Gv.  Changes in the extracellular potentials produced by unmyelinated nerve fibre resulting from alterations in the propagation velocity or the duration of the action potential. , 1987 .

[79]  S. Andreassen,et al.  Muscle fibre conduction velocity in motor units of the human anterior tibial muscle: a new size principle parameter. , 1987, The Journal of physiology.

[80]  P A Parker,et al.  Estimation of myoelectric conduction velocity distribution. , 1987, IEEE transactions on bio-medical engineering.

[81]  K H Kohn,et al.  A critical review of EMG-controlled electrical stimulation in paraplegics. , 1987, Critical reviews in biomedical engineering.

[82]  D. Downham,et al.  Practical analysis of variability of muscle function measurements in duchenne muscular dystrophy , 1987, Muscle & nerve.

[83]  G. Dimitrov.  Changes in the extracellular potentials produced by unmyelinated nerve fibre resulting from alterations in the propagation velocity or the duration of the action potential. , 1987, Electromyography and clinical neurophysiology.

[84]  R. Shumway,et al.  Carrier detection of Duchenne dystrophy by frequency analysis of the electromyogram. , 1988, Journal of biomedical engineering.

[85]  R. Merletti,et al.  Comparison between myoelectric signal mean and median frequency estimates , 1988, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[86]  Z. Lateva.  Dependence of quantitative parameters of the extracellular potential power spectrum on propagation velocity, duration and asymmetry of action potentials. , 1988, Electromyography and clinical neurophysiology.

[87]  M. Stokes,et al.  Human muscle fatigue: frequency dependence of excitation and force generation. , 1988, The Journal of physiology.

[88]  R. Merletti,et al.  Suppression of stimulation artifacts from myoelectric-evoked potential recordings , 1988, IEEE Transactions on Biomedical Engineering.

[89]  Lateva Zc.  Dependence of quantitative parameters of the extracellular potential power spectrum on propagation velocity, duration and asymmetry of action potentials. , 1988 .

[90]  V. Edgerton,et al.  Coexistent Hoffmann reflexes in human leg muscles are commonly due to volume conduction , 1988, Experimental Neurology.

[91]  R. C. Lehman,et al.  Electrical stimulation versus voluntary exercise in strengthening thigh musculature after anterior cruciate ligament surgery. , 1988, Physical therapy.

[92]  F Denoth,et al.  Differences between surface EMG in male and female subjects evidenced by automatic analysis. , 1988, Electroencephalography and clinical neurophysiology.

[93]  A. McComas,et al.  Relationship between numbers and frequencies of stimuli in human muscle fatigue. , 1988, Journal of applied physiology.

[94]  Massimo Frascarelli,et al.  EMG computerized analysis of localized fatigue in duchenne muscular dystrophy , 1988, Muscle & nerve.

[95]  Günther Rau,et al.  The influence of temperature and excitation pattern on noninvasively detected conduction velocity in single motor units , 1988, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[96]  C. D. De Luca,et al.  Surface myoelectric signal cross-talk among muscles of the leg. , 1988, Electroencephalography and clinical neurophysiology.

[97]  A. Kralj,et al.  Functional Electrical Stimulation: Standing and Walking after Spinal Cord Injury , 1989 .

[98]  Relationships between SMES PSD and ACF main lobe width in localized muscle fatigue evaluation , 1989, Images of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society,.

[99]  V A Convertino,et al.  Characteristics and preliminary observations of the influence of electromyostimulation on the size and function of human skeletal muscle during 30 days of simulated microgravity. , 1989, Aviation, space, and environmental medicine.

[100]  R. Mark,et al.  Functional electrical stimulation of the latissimus dorsi muscle for use in cardiac assist , 1989, IEEE Transactions on Biomedical Engineering.

[101]  L Arendt-Nielsen,et al.  Measurement of Muscle Fiber Conduction Velocity in Humans: Techniques and Applications , 1989, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[102]  M. Solomonow,et al.  Orderly stimulation of skeletal muscle motor units with tripolar nerve cuff electrode , 1989, IEEE Transactions on Biomedical Engineering.

[103]  Alan J. McComas,et al.  Prolongation of twitch potentiating mechanism throughout muscle fatigue and recovery , 1989, Experimental Neurology.

[104]  J. Duchateau,et al.  Muscle fatigue, effects of training and disuse , 1989, Muscle & nerve.

[105]  C. D. De Luca,et al.  Inference of motor unit recruitment order in voluntary and electrically elicited contractions. , 1990, Journal of applied physiology.

[106]  M Solomonow,et al.  Electromyogram power spectra frequencies associated with motor unit recruitment strategies. , 1990, Journal of applied physiology.

[107]  Knaflitz,et al.  Myoelectric manifestations of fatigue in voluntary and electrically elicited contractions. , 1990, Journal of applied physiology.

[108]  Paolo Bonato,et al.  Comparison between muscle fiber conduction velocity estimation techniques: spectral matching versus crosscorrelation , 1990 .

[109]  T Blogg,et al.  A digital technique for stimulus artifact reduction. , 1990, Electroencephalography and clinical neurophysiology.

[110]  J. Mortimer,et al.  A method to effect physiological recruitment order in electrically activated muscle , 1991, IEEE Transactions on Biomedical Engineering.

[111]  C J De Luca,et al.  pH-induced effects on median frequency and conduction velocity of the myoelectric signal. , 1991, Journal of applied physiology.

[112]  J. Mortimer,et al.  Selective activation of small motor axons by quasitrapezoidal current pulses , 1991, IEEE Transactions on Biomedical Engineering.

[113]  R Merletti,et al.  Indices of muscle fatigue. , 1991, Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology.

[114]  Ayse G. Canseven,et al.  Electrical Properties of The Skin , 1992 .

[115]  R. Merletti,et al.  Age related changes in surface myoelectric signals. , 2020, Scandinavian journal of rehabilitation medicine.

[116]  Stephen A. Dyer,et al.  Digital signal processing , 2018, 8th International Multitopic Conference, 2004. Proceedings of INMIC 2004..