Prediction of diazepam disposition in the rat and man by a physiologically based pharmacokinetic model
暂无分享,去创建一个
Yuichi Sugiyama | Tatsuji Iga | Yasufumi Sawada | Y. Sugiyama | Y. Sawada | T. Iga | Manabu Hanano | M. Hanano | Y. Igari | Yasutaka Igari
[1] E. Arnold. A simple method for determining diazepam and its major metabolites in biological fluids: application in bioavailability studies. , 2009, Acta pharmacologica et toxicologica.
[2] Y. Sawada,et al. In vitro and in vivo assessment of hepatic and extrahepatic metabolism of diazepam in the rat. , 1984, Journal of pharmaceutical sciences.
[3] Yuichi Sugiyama,et al. Physiological pharmacokinetics of ethoxybenzamide based on biochemical data obtainedin vitro as well as on physiological data , 1982, Journal of Pharmacokinetics and Biopharmaceutics.
[4] Y. Sawada,et al. Tissue distribution of 14C-diazepam and its metabolites in rats. , 1982, Drug metabolism and disposition: the biological fate of chemicals.
[5] D. Greenblatt,et al. Effects of desmethyldiazepam on diazepam kinetics: A study of effects of a metabolite on parent drug disposition , 1981, Clinical pharmacology and therapeutics.
[6] J. Lin,et al. Kinetic studies on the deethylation of ethoxybenzamide. A comparative study with isolated hepatocytes and liver microsomes of rat. , 1980, Biochemical pharmacology.
[7] J. Houston,et al. In vivo assessment of extrahepatic conjugative metabolism in first pass effects using the model compound phenol , 1980, The Journal of pharmacy and pharmacology.
[8] B. R. Smith,et al. Prediction of pulmonary benzo(a)pyrene 4,5-oxide clearance: a pharmacokinetic analysis of epoxide-metabolizing enzymes in rabbit lung. , 1980, The Journal of pharmacology and experimental therapeutics.
[9] R. Dedrick,et al. Nonlinear pharmacokinetic models for 5‐fluorouracil in man: Intravenous and intraperitoneal routes , 1980, Clinical pharmacology and therapeutics.
[10] H. Boxenbaum. Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin , 1980, Journal of Pharmacokinetics and Biopharmaceutics.
[11] Y. Sugiyama,et al. MULTIPLICITY OF SULFOBROMOPHTHALEIN-BINDING PROTEINS IN Y-FRACTION FROM RAT LIVER , 1979 .
[12] R. J. Lutz,et al. A review of the applications of physiologically based pharmacokinetic modeling , 1979, Journal of Pharmacokinetics and Biopharmaceutics.
[13] J. Gross,et al. Estimation of tissue-to-plasma partition coefficients used in physiological pharmacokinetic models , 1979, Journal of Pharmacokinetics and Biopharmaceutics.
[14] Jiunn H. Lin,et al. Correlation betweenin vitro andin vivo drug metabolism rate: Oxidation of ethoxybenzamide in rat , 1978, Journal of Pharmacokinetics and Biopharmaceutics.
[15] M Gibaldi,et al. Physiologically based pharmacokinetic model for digoxin disposition in dogs and its preliminary application to humans. , 1977, Journal of pharmaceutical sciences.
[16] R. Lutz,et al. A preliminary pharmacokinetic model for several chlorinated biphenyls in the rat. , 1977, Drug metabolism and disposition: the biological fate of chemicals.
[17] G R Wilkinson,et al. Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance. , 1977, The Journal of pharmacology and experimental therapeutics.
[18] K H Antonin,et al. Pharmacokinetics and plasma binding of diazepam in man, dog, rabbit, guinea pig and rat. , 1976, The Journal of pharmacology and experimental therapeutics.
[19] R. Roberts,et al. Computer simulation of sulfobromophthalein kinetics in the rat using flow-limited models with extrapolation to man , 1975, Journal of Pharmacokinetics and Biopharmaceutics.
[20] E. Mimnaugh,et al. Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species. , 1975, Drug metabolism and disposition: the biological fate of chemicals.
[21] U. Klotz,et al. The effects of age and liver disease on the disposition and elimination of diazepam in adult man. , 1975, The Journal of clinical investigation.
[22] W. Kalow,et al. Biliary excretion of diazepam in the rat. , 1974, Drug metabolism and disposition: the biological fate of chemicals.
[23] N. Benowitz,et al. Lidocaine disposition kinetics in monkey and man; I. Prediction by a perfusion model , 1974, Clinical pharmacology and therapeutics.
[24] Robert L. Dedrick,et al. Animal scale-up , 1973, Journal of Pharmacokinetics and Biopharmaceutics.
[25] J. Cannon,et al. Pharmacokinetics of 1-beta-D-arabinofuranosylcytosine (ARA-C) deamination in several species. , 1973, Biochemical pharmacology.
[26] D. Shand,et al. The disposition of propranolol. 3. Decreased half-life and volume of distribution as a result of plasma binding in man, monkey, dog and rat. , 1973, The Journal of pharmacology and experimental therapeutics.
[27] R. Lutz,et al. Transport and binding of methotrexate in vivo. , 1973, Journal of pharmaceutical sciences.
[28] S. Curry. Relation between binding to plasma protein, apparent volume of distribution, and rate constants of disposition and elimination for chlorpromazine in three species , 1972, The Journal of pharmacy and pharmacology.
[29] K. Bischoff,et al. Methotrexate pharmacokinetics. , 1971, Journal of pharmaceutical sciences.
[30] H. Wagner,et al. Measurement of the distribution of cardiac output in unanesthetized rats. , 1971, Journal of applied physiology.
[31] William S. Spector,et al. Handbook of Biological Data , 1957, The Yale Journal of Biology and Medicine.
[32] J. F. Gross,et al. Physiologically based pharmacokinetic models for anticancer drugs , 2004, Cancer Chemotherapy and Pharmacology.
[33] U. Klotz,et al. Clearance of diazepam can be impaired by its major metabolite desmethyldiazepam , 2004, European Journal of Clinical Pharmacology.
[34] R. Dedrick,et al. In vitro-in vivo correlation of drug metabolism--deamination of 1- -D-arabinofuranosylcytosine. , 1972, Biochemical pharmacology.
[35] D. Shand,et al. The Disposition of Propranolol , 1972 .
[36] K. Bischoff,et al. Thiopental pharmacokinetics. , 1968, Journal of pharmaceutical sciences.
[37] W W MAPLESON,et al. An electric analogue for uptake and exchange of inert gases and other agents. , 1963, Journal of applied physiology.