Regulatory Crosstalk of Doxorubicin, Estradiol and TNFα Combined Treatment in Breast Cancer-derived Cell Lines

[1]  M. Vieth,et al.  Loss of endogenous RNF43 function enhances proliferation and tumour growth of intestinal and gastric cells. , 2018, Carcinogenesis.

[2]  J. Carroll,et al.  Signaling pathways and steroid receptors modulating estrogen receptor α function in breast cancer , 2018, Genes & Development.

[3]  D. Menendez,et al.  ETV7-Mediated DNAJC15 Repression Leads to Doxorubicin Resistance in Breast Cancer Cells1 , 2018, Neoplasia.

[4]  D. Posthuma,et al.  Functional mapping and annotation of genetic associations with FUMA , 2017, Nature Communications.

[5]  Kim-Anh Lê Cao,et al.  mixOmics: An R package for ‘omics feature selection and multiple data integration , 2017, bioRxiv.

[6]  Xin-Qiu Yao,et al.  Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells. , 2017, Molecular cell.

[7]  Melissa J. Morine,et al.  Systems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules , 2016, Scientific Reports.

[8]  V. Seshan,et al.  TNF is a key cytokine mediating neutrophil cytotoxic activity in breast cancer patients , 2016, npj Breast Cancer.

[9]  J. Mesirov,et al.  The Molecular Signatures Database Hallmark Gene Set Collection , 2015 .

[10]  A. Fukui,et al.  Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling , 2015, Molecular and Cellular Biology.

[11]  Tao Jiang,et al.  Differential regulation enrichment analysis via the integration of transcriptional regulatory network and gene expression data , 2015, Bioinform..

[12]  A. Inga,et al.  Cooperative interactions between p 53 and NFκB enhance cell plasticity , 2014 .

[13]  A. Inga,et al.  p53-directed translational control can shape and expand the universe of p53 target genes , 2014, Cell Death and Differentiation.

[14]  A. Inga,et al.  ∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. , 2014 .

[15]  David Chen,et al.  ESR1 ligand binding domain mutations in hormone-resistant breast cancer , 2013, Nature Genetics.

[16]  M. A. Resnick,et al.  Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics , 2013, Cell cycle.

[17]  Henryk Maciejewski,et al.  Gene set analysis methods: statistical models and methodological differences , 2013, Briefings Bioinform..

[18]  M De Bortoli,et al.  Targeting of the adaptor protein Tab2 as a novel approach to revert tamoxifen resistance in breast cancer cells , 2012, Oncogene.

[19]  H. Nam,et al.  TNF alpha-induced down-regulation of estrogen receptor alpha in MCF-7 breast cancer cells. , 2008, Molecules and cells.

[20]  A. Ratto,et al.  17β-Estradiol Promotes Breast Cancer Cell Proliferation-Inducing Stromal Cell-Derived Factor-1-Mediated Epidermal Growth Factor Receptor Transactivation: Reversal by Gefitinib Pretreatment , 2008, Molecular Pharmacology.

[21]  D. Tatomer,et al.  Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression. , 2006, Molecular cell.

[22]  Pablo Tamayo,et al.  Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[23]  G. Leclercq,et al.  Opposite effects of estrogen receptors alpha and beta on MCF-7 sensitivity to the cytotoxic action of TNF and p53 activity , 2005, Oncogene.

[24]  Florian Sohler,et al.  Identifying Active Transcription Factors and Kinases from Expression Data Using Pathway Queries , 2022 .

[25]  Joy Joseph,et al.  Doxorubicin Induces Apoptosis in Normal and Tumor Cells via Distinctly Different Mechanisms , 2004, Journal of Biological Chemistry.

[26]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[27]  R. Dantzer,et al.  Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor. , 2002, Cancer research.

[28]  Yan Tang,et al.  Oestrogen-mediated suppression of tumour necrosis factor alpha-induced apoptosis in MCF-7 cells: subversion of Bcl-2 by anti-oestrogens , 2001, The Journal of Steroid Biochemistry and Molecular Biology.

[29]  C. Klinge.  Estrogen receptor interaction with estrogen response elements. , 2001, Nucleic acids research.

[30]  J. Sloane,et al.  Estrogen receptor-positive proliferating cells in the normal and precancerous breast. , 1999, The American journal of pathology.

[31]  C. Moyret-Lalle,et al.  Resistance of MCF7 human breast carcinoma cells to TNF-induced cell death is associated with loss of p53 function , 1997, Oncogene.

[32]  J. Mesirov,et al.  The Molecular Signatures Database (MSigDB) hallmark gene set collection. , 2015, Cell systems.