Program and Book of Abstracts

Electroretinogram, LED, microelectrode, retina, cornea Electroretinogram (ERG) measurements show voltage signals emitted by light-sensitive cells in the retina of the eye. These recordings have clinical significance since they can be used to determine physiological abnormalities in vision. ERG data is collected by placing an electrode on the cornea and repetitively flashing a LED light. A problem with this procedure is the rat’s eye is very small which makes the set up tedious and time-consuming. An LED and microelectrode placing apparatus was designed and constructed to reduce the setting up time, increase precision of set up and guarantee fixation. Two L-shaped clips adapt to a plastic platform wherever desired. One of the clips holds the LED light and the other one holds the microelectrode directly on the eye. The clips have six degrees of freedom, which allows flexibility of approximation and direction of both the LED light and the microelectrode. The apparatus was successfully used to record ERGs from rat eyes, and it was found that an ERG signal could even be picked up when light is flashed to the opposite eye. A plastic coupler was designed to assure light was only delivered to one eye. The data showed that there is a measurable ERG from crossed light flashing, something that has not yet been demonstrated in vision related research. This signal must come from retinal ganglion cells, and could thereby become a measure for tracking ganglion cell health in diseases like glaucoma. Materials Science, MEMS/NEMS, Nanotechnology, Biomedical, and Health 74 Distributed Switched Capacitor DC-DC Converter for High Power Efficiency and Low Noise Orhun Aras Uzun, Selçuk Köse Department of Electrical Engineering orhunuzun@mail.usf.edu

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