Parametric analysis of the biomechanical response of head subjected to the primary blast loading – a data mining approach

Abstract Traumatic brain injury due to primary blast loading has become a signature injury in recent military conflicts and terrorist activities. Extensive experimental and computational investigations have been conducted to study the interrelationships between intracranial pressure response and intrinsic or ‘input’ parameters such as the head geometry and loading conditions. However, these relationships are very complicated and are usually implicit and ‘hidden’ in a large amount of simulation/test data. In this study, a data mining method is proposed to explore such underlying information from the numerical simulation results. The heads of different species are described as a highly simplified two-part (skull and brain) finite element model with varying geometric parameters. The parameters considered include peak incident pressure, skull thickness, brain radius and snout length. Their interrelationship and coupling effect are discovered by developing a decision tree based on the large simulation data-set. The results show that the proposed data-driven method is superior to the conventional linear regression method and is comparable to the nonlinear regression method. Considering its capability of exploring implicit information and the relatively simple relationships between response and input variables, the data mining method is considered to be a good tool for an in-depth understanding of the mechanisms of blast-induced brain injury. As a general method, this approach can also be applied to other nonlinear complex biomechanical systems.

[1]  Cynthia Bir,et al.  Development of an FE model of the rat head subjected to air shock loading. , 2010, Stapp car crash journal.

[2]  Kazuyoshi Takayama,et al.  Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research. , 2011, Journal of neurotrauma.

[3]  Louis French,et al.  Traumatic brain injury in the war zone. , 2005, The New England journal of medicine.

[4]  Tao Yang,et al.  Development of a rat model for studying blast-induced traumatic brain injury , 2010, Journal of the Neurological Sciences.

[5]  Albert I. King,et al.  SOME CONSIDERATIONS ON THE THRESHOLD AND INTER-SPECIES SCALING LAW FOR PRIMARY BLAST-INDUCED TRAUMATIC BRAIN INJURY: A SEMI-ANALYTICAL APPROACH , 2013 .

[6]  D. Edwards Data Mining: Concepts, Models, Methods, and Algorithms , 2003 .

[7]  D. Meaney,et al.  The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden. , 2014, Journal of biomechanical engineering.

[8]  R. Bauman,et al.  Blast overpressure in rats: recreating a battlefield injury in the laboratory. , 2009, Journal of neurotrauma.

[9]  Paul A Taylor,et al.  Simulation of blast-induced early-time intracranial wave physics leading to traumatic brain injury. , 2009, Journal of biomechanical engineering.

[10]  Garrett W. Wood,et al.  Brain Injuries from Blast , 2011, Annals of Biomedical Engineering.

[11]  M. Ziejewski,et al.  Biomechanical Assessment of Brain Dynamic Responses Due to Blast Pressure Waves , 2010, Annals of Biomedical Engineering.

[12]  King H. Yang,et al.  A theoretical analysis of stress wave propagation in the head under primary blast loading , 2014, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[13]  อนิรุธ สืบสิงห์,et al.  Data Mining Practical Machine Learning Tools and Techniques , 2014 .

[14]  Fredrik Arrhén,et al.  Neuropathology and pressure in the pig brain resulting from low-impulse noise exposure. , 2008, Journal of neurotrauma.

[15]  Xin Jin,et al.  Using a gel/plastic surrogate to study the biomechanical response of the head under air shock loading: a combined experimental and numerical investigation , 2012, Biomechanics and modeling in mechanobiology.

[16]  King H. Yang,et al.  Biomechanical responses of a pig head under blast loading: a computational simulation , 2013, International journal for numerical methods in biomedical engineering.

[17]  M. Philippens,et al.  Physics of IED Blast Shock Tube Simulations for mTBI Research , 2011, Front. Neur..

[18]  Richard M. McCarron,et al.  Measurement of blast wave by a miniature fiber optic pressure transducer in the rat brain , 2007, Journal of Neuroscience Methods.

[19]  Matthew B Panzer,et al.  Survival risk assessment for primary blast exposures to the head. , 2011, Journal of neurotrauma.

[20]  Michael S. Jaffee,et al.  Computational biology — Modeling of primary blast effects on the central nervous system , 2009, NeuroImage.

[21]  Yves Tillé,et al.  Sampling Algorithms , 2011, International Encyclopedia of Statistical Science.

[22]  Rocco Armonda,et al.  An introductory characterization of a combat-casualty-care relevant swine model of closed head injury resulting from exposure to explosive blast. , 2009, Journal of neurotrauma.

[23]  William C Moss,et al.  Skull flexure from blast waves: a mechanism for brain injury with implications for helmet design. , 2008, Physical review letters.

[24]  Pamela J VandeVord,et al.  Intracranial pressure increases during exposure to a shock wave. , 2011, Journal of neurotrauma.

[25]  L. Gu,et al.  Experimental and Numerical Investigation of the Mechanism of Blast Wave Transmission Through a Surrogate Head , 2014 .

[26]  Rocco Armonda,et al.  An introductory characterization of a combat-casualty-care relevant swine model of closed head injury resulting from exposure to explosive blast. , 2009, Journal of neurotrauma.