Delivery of Functional Anti-miR-9 by Mesenchymal Stem Cell–derived Exosomes to Glioblastoma Multiforme Cells Conferred Chemosensitivity

[1]  Steven J. Greco,et al.  Exogenous CXCL12 activates protein kinase C to phosphorylate connexin 43 for gap junctional intercellular communication among confluent breast cancer cells. , 2013, Cancer letters.

[2]  C. N. Coleman,et al.  Fractionated Radiation Alters Oncomir and Tumor Suppressor miRNAs in Human Prostate Cancer Cells , 2012, Radiation research.

[3]  Aled Clayton,et al.  Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids , 2006, Current protocols in cell biology.

[4]  P. Rameshwar,et al.  Veto-Like Activity of Mesenchymal Stem Cells: Functional Discrimination Between Cellular Responses to Alloantigens and Recall Antigens1 , 2003, The Journal of Immunology.

[5]  Corinne E Griguer,et al.  Acquisition of Chemoresistance in Gliomas Is Associated with Increased Mitochondrial Coupling and Decreased ROS Production , 2011, PloS one.

[6]  G. Schackert,et al.  A MDR1 (ABCB1) gene single nucleotide polymorphism predicts outcome of temozolomide treatment in glioblastoma patients. , 2009, Annals of oncology : official journal of the European Society for Medical Oncology.

[7]  G. Juszczak,et al.  Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: Animal and human studies , 2009, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[8]  M. Matúšková,et al.  HSV-tk expressing mesenchymal stem cells exert bystander effect on human glioblastoma cells. , 2010, Cancer letters.

[9]  Tae-Min Kim,et al.  A developmental taxonomy of glioblastoma defined and maintained by MicroRNAs. , 2011, Cancer research.

[10]  H. Allgayer,et al.  MicroRNAs in cancer: small molecules, big chances. , 2012, Anti-cancer agents in medicinal chemistry.

[11]  Y. Cheng,et al.  New therapeutic approaches for malignant glioma: in search of the Rosetta stone , 2012, F1000 medicine reports.

[12]  I. Nakano,et al.  Glioma stem cells: their role in chemoresistance. , 2012, World neurosurgery.

[13]  D. Bexell,et al.  Stem cell-based therapy for malignant glioma. , 2013, Cancer treatment reviews.

[14]  Jingxuan Yang,et al.  Deregulated Signaling Pathways in Glioblastoma Multiforme: Molecular Mechanisms and Therapeutic Targets , 2012, Cancer investigation.

[15]  Steven J. Greco,et al.  Mesenchymal stem cells in drug/gene delivery: implications for cell therapy. , 2012, Therapeutic delivery.

[16]  C. Hsieh,et al.  Tumor cycling hypoxia induces chemoresistance in glioblastoma multiforme by upregulating the expression and function of ABCB1. , 2012, Neuro-oncology.

[17]  Atique U. Ahmed,et al.  MicroRNA targeting as a therapeutic strategy against glioma. , 2013, Current molecular medicine.

[18]  Sidhartha Hazari,et al.  Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298. , 2012, The American journal of pathology.

[19]  N. Nardi,et al.  Biology and applications of Mesenchymal Stem Cells , 2010, Science progress.

[20]  M. Ringnér,et al.  Exosomes reflect the hypoxic status of glioma cells and mediate hypoxia-dependent activation of vascular cells during tumor development , 2013, Proceedings of the National Academy of Sciences.

[21]  G. Camussi,et al.  Therapeutic potential of mesenchymal stem cell-derived microvesicles. , 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[22]  D. Chesler,et al.  Mesenchymal Stem Cells Derived from Adipose Tissue vs Bone Marrow: In Vitro Comparison of Their Tropism towards Gliomas , 2013, PloS one.

[23]  R. Herrmann,et al.  A phase 2 study of allogeneic mesenchymal stromal cells for luminal Crohn's disease refractory to biologic therapy. , 2014, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[24]  G. Crabtree,et al.  MicroRNAs: regulators of neuronal fate. , 2013, Current opinion in cell biology.

[25]  Steven J. Greco,et al.  Gap junction-mediated import of microRNA from bone marrow stromal cells can elicit cell cycle quiescence in breast cancer cells. , 2011, Cancer research.

[26]  A. Orlacchio,et al.  MicroRNA Implications across Neurodevelopment and Neuropathology , 2009, Journal of biomedicine & biotechnology.

[27]  L. Moreno,et al.  Activation of neutral sphingomyelinase is involved in acute hypoxic pulmonary vasoconstriction , 2008, Cardiovascular research.