Deficiency of large tumor suppressor kinase 1 causes congenital hearing loss associated with cochlear abnormalities in mice.

[1]  N. Segil,et al.  Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal , 2020, Proceedings of the National Academy of Sciences.

[2]  H. Kojima,et al.  L1CAM-ILK-YAP mechanotransduction drives proliferative activity of epithelial cells in middle ear cholesteatoma. , 2020, The American journal of pathology.

[3]  J. T. Corwin,et al.  YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice , 2020, The Journal of Neuroscience.

[4]  G. Christofori,et al.  LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function , 2019, Nature Communications.

[5]  Yonggang Zheng,et al.  The Hippo Signaling Pathway in Development and Disease. , 2019, Developmental cell.

[6]  Xiaowei Lu,et al.  Par3 is essential for the establishment of planar cell polarity of inner ear hair cells , 2019, Proceedings of the National Academy of Sciences.

[7]  Yu-xiang Fang,et al.  Loss of Par3 promotes prostatic tumorigenesis by enhancing cell growth and changing cell division modes , 2018, Oncogene.

[8]  Xiao Yu,et al.  The role of G protein-coupled receptors in cochlear planar cell polarity. , 2016, The international journal of biochemistry & cell biology.

[9]  N. Tapon,et al.  The Hippo Pathway Core Cassette Regulates Asymmetric Cell Division , 2015, Current Biology.

[10]  J. Sage,et al.  Control of Proliferation and Cancer Growth by the Hippo Signaling Pathway , 2015, Molecular Cancer Research.

[11]  D. Corey,et al.  Gene Expression by Mouse Inner Ear Hair Cells during Development , 2015, The Journal of Neuroscience.

[12]  E. Guccione,et al.  Zebrafish yap1 plays a role in differentiation of hair cells in posterior lateral line , 2014, Scientific Reports.

[13]  Martin S. Taylor,et al.  Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects. , 2014, American journal of human genetics.

[14]  M. Cayouette,et al.  A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. , 2013, Developmental cell.

[15]  Y. Hata,et al.  What is the Hippo pathway? Is the Hippo pathway conserved in Caenorhabditis elegans? , 2013, Journal of biochemistry.

[16]  M. Montcouquiol,et al.  Revisiting planar cell polarity in the inner ear. , 2013, Seminars in cell & developmental biology.

[17]  H. Okano,et al.  Notch Inhibition Induces Cochlear Hair Cell Regeneration and Recovery of Hearing after Acoustic Trauma , 2013, Neuron.

[18]  G. Halder,et al.  Regulation of the Hippo pathway by cell architecture and mechanical signals. , 2012, Seminars in cell & developmental biology.

[19]  H. Saya,et al.  LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression , 2012, Journal of Cell Biology.

[20]  H. Okano,et al.  Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea , 2010, Neuroscience Research.

[21]  K. Ogawa,et al.  Balance dysfunction resulting from acute inner ear energy failure is caused primarily by vestibular hair cell damage , 2009, Journal of neuroscience research.

[22]  Matias Simons,et al.  Planar cell polarity signaling: from fly development to human disease. , 2008, Annual review of genetics.

[23]  K. Harvey,et al.  Fat Cadherin Modulates Organ Size in Drosophila via the Salvador/Warts/Hippo Signaling Pathway , 2006, Current Biology.

[24]  R. Fehon,et al.  Delineation of a Fat tumor suppressor pathway , 2006, Nature Genetics.

[25]  H. Okano,et al.  Proinflammatory cytokines expression in noise‐induced damaged cochlea , 2006, Journal of neuroscience research.

[26]  K. Ogawa,et al.  Nuclear factor-kappa B nuclear translocation in the cochlea of mice following acoustic overstimulation , 2006, Brain Research.

[27]  Jianbin Huang,et al.  The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP , 2005, Cell.

[28]  Shian Wu,et al.  hippo Encodes a Ste-20 Family Protein Kinase that Restricts Cell Proliferation and Promotes Apoptosis in Conjunction with salvador and warts , 2003, Cell.

[29]  I. Hariharan,et al.  The Drosophila Mst Ortholog, hippo, Restricts Growth and Cell Proliferation and Promotes Apoptosis , 2003, Cell.

[30]  W. Tao,et al.  Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction , 1999, Nature Genetics.

[31]  T. Xu,et al.  Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase. , 1995, Development.

[32]  P J Bryant,et al.  The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation. , 1995, Genes & development.

[33]  R. Ramsden,et al.  Hearing Loss , 2017, Quick Reference Guide to Pediatric Care.

[34]  J. T. Corwin,et al.  Regenerative proliferation in inner ear sensory epithelia from adult guinea pigs and humans. , 1993, Science.

[35]  J. T. Corwin,et al.  Ultrastructural evidence for hair cell regeneration in the mammalian inner ear. , 1993, Science.

[36]  J. Nadol Medical progress : hearing loss , 1993 .

[37]  D J DeRosier,et al.  Actin filaments, stereocilia, and hair cells: how cells count and measure. , 1992, Annual review of cell biology.