Magnetic Nanoparticle Based Interface for Molecular Communication Systems

Molecular communication systems enable promising applications, such as the monitoring of the human organs at nanoscale. An open issue in this context is the design of a practical interface between the biological system inside the body and an RF-based backhaul, which would enable an uplink connection to a central processing unit. In this letter, we present an interface based on magnetic nanoparticles released by a nanomachine inside a blood vessel of a finger and sensed by an attached susceptometer. Our numerical evaluations show that the proposed method achieves a high performance in terms of detection accuracy and power consumption.

[1]  Harald Unterweger,et al.  Magnetic nanoparticle-based drug delivery for cancer therapy. , 2015, Biochemical and biophysical research communications.

[2]  Ian F. Akyildiz,et al.  Nanonetworks: A new communication paradigm , 2008, Comput. Networks.

[3]  Kai Mesa,et al.  Essential Cell Biology , 2015, The Yale Journal of Biology and Medicine.

[4]  Q. Pankhurst,et al.  TOPICAL REVIEW: Applications of magnetic nanoparticles in biomedicine , 2003 .

[5]  Tatsuya Suda,et al.  Externally Controllable Molecular Communication , 2014, IEEE Journal on Selected Areas in Communications.

[6]  P. Barat,et al.  Innovative Instrumentation to Measure Magnetic Susceptibility , 2013, IEEE Transactions on Magnetics.

[7]  B. Scaife,et al.  The field dependence of the complex frequency-dependent susceptibility of magnetic fluids , 1988 .

[8]  Y. Koucheryavy,et al.  The internet of Bio-Nano things , 2015, IEEE Communications Magazine.

[9]  Nonlinear dynamic susceptibilities of interacting and noninteracting magnetic nanoparticles , 1998, cond-mat/9812143.

[10]  Hao Zeng,et al.  Size-controlled synthesis of magnetite nanoparticles. , 2002, Journal of the American Chemical Society.

[11]  B. Scaife,et al.  A study of the complex susceptibility of ferrofluids and rotational Brownian motion , 1987 .

[12]  R. Rosenson,et al.  Distribution of blood viscosity values and biochemical correlates in healthy adults. , 1994, Clinical chemistry.

[13]  A. Munir,et al.  FEM analysis of magnetic agitation for tagging biomolecules with magnetic nanoparticles in a microfluidic system , 2014 .

[14]  E. Tzirtzilakis,et al.  A mathematical model for blood flow in magnetic field , 2005 .

[15]  S. Sonkusale,et al.  A miniaturized AC magnetic susceptometer for detecting biomolecules tagged to magnetic nanoparticles , 2009, 2009 IEEE 35th Annual Northeast Bioengineering Conference.

[16]  B. Scaife,et al.  RAPID COMMUNICATION: New technique for measuring the complex susceptibility of ferrofluids , 1986 .

[17]  A. Vasilakos,et al.  Molecular Communication and Networking: Opportunities and Challenges , 2012, IEEE Transactions on NanoBioscience.