Sertoli cell-derived extracellular vesicles traverse the blood-testis barrier and deliver miR-24-3p inhibitor into germ cells improving sperm mobility.

[1]  D. Irvine,et al.  Cholesterol‐Amino‐Phosphate (CAP) Derived Lipid Nanoparticles for Delivery of Self‐Amplifying RNA and Restoration of Spermatogenesis in Infertile Mice , 2023, Advanced science.

[2]  Hao Wang,et al.  Engineered small extracellular vesicles as a versatile platform to efficiently load ferulic acid via an “esterase-responsive active loading” strategy , 2022, Frontiers in Bioengineering and Biotechnology.

[3]  Jacques Young,et al.  Androgens and spermatogenesis. , 2022, Annales d'endocrinologie.

[4]  Hongbo Chen,et al.  Small Extracellular Vesicles Derived From MSCs Have Immunomodulatory Effects to Enhance Delivery of ASO-210 for Psoriasis Treatment , 2022, Frontiers in Cell and Developmental Biology.

[5]  A. Clayton,et al.  Challenges and directions in studying cell–cell communication by extracellular vesicles , 2022, Nature Reviews Molecular Cell Biology.

[6]  Lizeng Gao,et al.  Ferritin-Nanocaged ATP Traverses the Blood-Testis Barrier and Enhances Sperm Motility in an Asthenozoospermia Model. , 2022, ACS nano.

[7]  J. Lötvall,et al.  A brief history of nearly EV‐erything – The rise and rise of extracellular vesicles , 2021, Journal of extracellular vesicles.

[8]  Guohui Zhang,et al.  Differentially expressed miRNAs and potential therapeutic targets for asthenospermia , 2021, Andrologia.

[9]  Xihui Sheng,et al.  Epididymal mRNA and miRNA transcriptome analyses reveal important genes and miRNAs related to sperm motility in roosters , 2021, Poultry science.

[10]  Hai-dong Guo,et al.  Effects of exosomal miRNAs in the diagnosis and treatment of Alzheimer’s disease , 2021, Mechanisms of Ageing and Development.

[11]  J. Olefsky,et al.  Exosomes as mediators of intercellular crosstalk in metabolism. , 2021, Cell metabolism.

[12]  F. Cheng,et al.  Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys , 2021, Theranostics.

[13]  Yabing Chen,et al.  Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells , 2021, Theranostics.

[14]  Xiaoyun He,et al.  Emerging roles of exosomal miRNAs in diabetes mellitus , 2021, Clinical and translational medicine.

[15]  Yabing Chen,et al.  Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells. , 2021, Journal of hazardous materials.

[16]  S. A. Muhammad,et al.  Are extracellular vesicles new hope in clinical drug delivery for neurological disorders? , 2021, Neurochemistry International.

[17]  Junfeng Zhang,et al.  Pancreatic β cells control glucose homeostasis via the secretion of exosomal miR‐29 family , 2021, Journal of extracellular vesicles.

[18]  A. Papatsoris,et al.  Role of total motile sperm count in the evaluation of young men with bilateral subclinical varicocele and asthenospermia. , 2020, Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica.

[19]  J. Zaro,et al.  Advances in Exosome-Based Drug Delivery and Tumor Targeting: From Tissue Distribution to Intracellular Fate , 2020, International journal of nanomedicine.

[20]  M. He,et al.  URG4 mediates cell proliferation and cell cycle in osteosarcoma via GSK3β/β-catenin/cyclin D1 signaling pathway , 2020, Journal of Orthopaedic Surgery and Research.

[21]  Siyuan Cao,et al.  Mitochondria-related miR-574 reduces sperm ATP by targeting ND5 in aging males , 2020, Aging.

[22]  E. Sakhinia,et al.  MicroRNAs association with azoospermia, oligospermia, asthenozoospermia, and teratozoospermia: a systematic review , 2020, Journal of Assisted Reproduction and Genetics.

[23]  S. Z. Shahrokhi,et al.  Asthenozoospermia: Cellular and molecular contributing factors and treatment strategies , 2020, Andrologia.

[24]  A. Aversa,et al.  Evaluation of Sperm Mitochondrial Function: A Key Organelle for Sperm Motility , 2020, Journal of clinical medicine.

[25]  Yabing Chen,et al.  m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells , 2020, Autophagy.

[26]  Weifeng Mao,et al.  GSK-3β in DNA repair, apoptosis, and resistance of chemotherapy, radiotherapy of cancer. , 2020, Biochimica et biophysica acta. Molecular cell research.

[27]  Yuanyuan Fu,et al.  Pretreatment with Roxadustat (FG-4592) Attenuates Folic Acid-Induced Kidney Injury through Antiferroptosis via Akt/GSK-3β/Nrf2 Pathway , 2020, Oxidative medicine and cellular longevity.

[28]  F. Zhang,et al.  A DNAH17 missense variant causes flagella destabilization and asthenozoospermia , 2019, The Journal of experimental medicine.

[29]  Yi Zheng,et al.  Glycogen Synthase Kinase-3 Regulates Sperm Motility and Acrosome Reaction via Affecting Energy Metabolism in Goats , 2019, Front. Physiol..

[30]  M. J. Freitas,et al.  Isoform-specific GSK3A activity is negatively correlated with human sperm motility , 2019, Molecular human reproduction.

[31]  M. Nasr-Esfahani,et al.  Effects of N-acetyl-cysteine supplementation on sperm quality, chromatin integrity and level of oxidative stress in infertile men , 2019, Reproductive Biology and Endocrinology.

[32]  T. Qi,et al.  Expressions of miR‐525‐3p and its target gene SEMG1 in the spermatozoa of patients with asthenozoospermia , 2018, Andrology.

[33]  N. Yang,et al.  Identification and differential expression of microRNAs in the testis of chicken with high and low sperm motility. , 2018, Theriogenology.

[34]  Ling Zhang,et al.  Dopamine‐loaded blood exosomes targeted to brain for better treatment of Parkinson's disease , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[35]  M. Ożgo,et al.  Sperm mitochondrial dysfunction and oxidative stress as possible reasons for isolated asthenozoospermia. , 2018, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[36]  J. Gui,et al.  An miR-200 Cluster on Chromosome 23 Regulates Sperm Motility in Zebrafish , 2018, Endocrinology.

[37]  Yabing Chen,et al.  Microcystin–leucine–arginine causes blood–testis barrier disruption and degradation of occludin mediated by matrix metalloproteinase-8 , 2018, Cellular and Molecular Life Sciences.

[38]  Xu-fang Liang,et al.  miR-34a Regulates Sperm Motility in Zebrafish , 2017, International journal of molecular sciences.

[39]  S. L'Hernault,et al.  Spermatogenesis , 2017, Current Biology.

[40]  Hui Xia,et al.  MicroRNA-27a-mediated repression of cysteine-rich secretory protein 2 translation in asthenoteratozoospermic patients , 2016, Asian journal of andrology.

[41]  Arkasubhra Ghosh,et al.  Contemporary Animal Models For Human Gene Therapy Applications. , 2015, Current gene therapy.

[42]  C. Cheng,et al.  The Mammalian Blood-Testis Barrier: Its Biology and Regulation. , 2015, Endocrine reviews.

[43]  S. Abdelrahman,et al.  Combination of vitamin E and clomiphene citrate in treating patients with idiopathic oligoasthenozoospermia: A prospective, randomized trial , 2015, Andrology.

[44]  W. Petok.  Infertility counseling (or the lack thereof) of the forgotten male partner. , 2015, Fertility and sterility.

[45]  Ashok Agarwal,et al.  A unique view on male infertility around the globe , 2015, Reproductive Biology and Endocrinology.

[46]  K. Nadeau,et al.  Lessons learned from mice and man: mimicking human allergy through mouse models. , 2014, Clinical immunology.

[47]  Z. Cai,et al.  Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection , 2014, Science Translational Medicine.

[48]  Z. Wang,et al.  Blood-testis barrier and spermatogenesis: lessons from genetically-modified mice , 2014, Asian journal of andrology.

[49]  Xiaoshan Feng,et al.  The Role of Glycogen Synthase Kinase 3-β in Immunity and Cell Cycle: Implications in Esophageal Cancer , 2013, Archivum Immunologiae et Therapiae Experimentalis.

[50]  M. Safarinejad,et al.  Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study. , 2012, The Journal of urology.

[51]  A. Agarwal,et al.  Small RNA in spermatogenesis and male infertility. , 2012, Frontiers in bioscience.

[52]  D. Sibley,et al.  The Blood-Testis Barrier and Its Implications for Male Contraception , 2012, Pharmacological Reviews.

[53]  T. Safranski,et al.  Differential expression of porcine sperm microRNAs and their association with sperm morphology and motility. , 2011, Theriogenology.

[54]  F. Shidfar,et al.  Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: A randomized double-blind, placebo controlled trial , 2011, Journal of endocrinological investigation.

[55]  David J. Begley,et al.  Structure and function of the blood–brain barrier , 2010, Neurobiology of Disease.

[56]  L. Multigner,et al.  Pentoxifylline and antioxidants improve sperm quality in male patients with varicocele. , 2009, Fertility and sterility.

[57]  J. Mendell.  MicroRNAs: Critical Regulators of Development, Cellular Physiology and Malignancy , 2005, Cell cycle.

[58]  OUP accepted manuscript , 2022, Neuro-Oncology.

[59]  Bo Zheng,et al.  Drug transport across the blood-testis barrier. , 2022, American journal of translational research.

[60]  Yang Yang,et al.  Expression of NDUFA13 in asthenozoospermia and possible pathogenesis. , 2017, Reproductive biomedicine online.