Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors.
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[1] Y. Rojanasakul,et al. Induction of TNFα in macrophages by vanadate is dependent on activation of transcription factor NF-κB and free radical reactions , 1999, Molecular and Cellular Biochemistry.
[2] C. Sen. Glutathione homeostasis in response to exercise training and nutritional supplements , 1999, Molecular and Cellular Biochemistry.
[3] J. Haddad. Oxygen homeostasis, thiol equilibrium and redox regulation of signalling transcription factors in the alveolar epithelium. , 2002, Cellular signalling.
[4] J. Haddad. Recombinant human interleukin (IL)-1 beta-mediated regulation of hypoxia-inducible factor-1 alpha (HIF-1 alpha) stabilization, nuclear translocation and activation requires an antioxidant/reactive oxygen species (ROS)-sensitive mechanism. , 2002, European cytokine network.
[5] J. Haddad. Nuclear factor (NF)-κB blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1β biosynthesis in alveolar epithelial cells , 2002 .
[6] J. Haddad,et al. Nuclear factor-kappa B-independent regulation of lipopolysaccharide-mediated interleukin-6 biosynthesis. , 2002, Biochemical and biophysical research communications.
[7] J. Haddad. RECOMBINANT TNF-α MEDIATED REGULATION OF THE IκB-α/NF-κB SIGNALING PATHWAY: EVIDENCE FOR THE ENHANCEMENT OF PRO- AND ANTI-INFLAMMATORY CYTOKINES IN ALVEOLAR EPITHELIAL CELLS , 2002 .
[8] J. Haddad,et al. Redox regulation of TNF-α biosynthesis: Augmentation by irreversible inhibition of γ-glutamylcysteine synthetase and the involvement of an IκB-α/NF-κB-independent pathway in alveolar epithelial cells , 2002 .
[9] N. Kernohan,et al. Direct comparison of the nature of mouse and human GST T1-1 and the implications on dichloromethane carcinogenicity. , 2002, Toxicology and applied pharmacology.
[10] Irfan Rahman,et al. PM10-exposed macrophages stimulate a proinflammatory response in lung epithelial cells via TNF-α , 2002 .
[11] J. Haddad,et al. Immunopharmacological potential of selective phosphodiesterase inhibition. II. Evidence for the involvement of an inhibitory-kappaB/nuclear factor-kappaB-sensitive pathway in alveolar epithelial cells. , 2002, The Journal of pharmacology and experimental therapeutics.
[12] J. Haddad,et al. Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells. , 2002, Antioxidants & redox signaling.
[13] J. Haddad,et al. Immunopharmacological potential of selective phosphodiesterase inhibition. I. Differential regulation of lipopolysaccharide-mediated proinflammatory cytokine (interleukin-6 and tumor necrosis factor-alpha) biosynthesis in alveolar epithelial cells. , 2002, The Journal of pharmacology and experimental therapeutics.
[14] Yasushi Matsumura,et al. Involvement of Nuclear Factor-&kgr;B and Apoptosis Signal-Regulating Kinase 1 in G-Protein–Coupled Receptor Agonist–Induced Cardiomyocyte Hypertrophy , 2002, Circulation.
[15] J. Magdalou,et al. Glucosamine modulates IL‐1‐induced activation of rat chondrocytes at a receptor level, and by inhibiting the NF‐κB pathway , 2002, FEBS letters.
[16] J. Haddad. The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production. , 2002, Biochemical pharmacology.
[17] L. Tacchini,et al. Activation of transcription factors by drugs inducing oxidative stress in rat liver. , 2002, Biochemical pharmacology.
[18] I. Rahman,et al. Glutathione and p53 independently mediate responses against oxidative stress in ES cells. , 2002, Free radical biology & medicine.
[19] A. Harris,et al. A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis , 2002, Oncogene.
[20] J. Haddad,et al. Redox/ROS regulation of lipopolysaccharide‐induced mitogen‐activated protein kinase (MAPK) activation and MAPK‐mediated TNF‐α biosynthesis , 2002, British journal of pharmacology.
[21] C. Kretz-remy,et al. Gene expression and thiol redox state. , 1999, Methods in enzymology.
[22] J. Haddad,et al. Amiloride Blockades Lipopolysaccharide-Induced Proinflammatory Cytokine Biosynthesis in an I κ B- α /NF- κ B–Dependent Mechanism: Evidence for the Amplification of an Antiinflammatory Pathway in the Alveolar Epithelium , 2002 .
[23] J. Haddad,et al. L-Buthionine-(S,R)-sulfoximine, an irreversible inhibitor of gamma-glutamylcysteine synthetase, augments LPS-mediated pro-inflammatory cytokine biosynthesis: evidence for the implication of an IkappaB-alpha/NF-kappaB insensitive pathway. , 2002, European cytokine network.
[24] M. McMahon,et al. Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention. , 2001, Cancer letters.
[25] H. Pinedo,et al. Induction of Vascular Endothelial Growth Factor Expression and Hypoxia-inducible Factor 1α Protein by the Oxidative Stressor Arsenite* , 2001, The Journal of Biological Chemistry.
[26] N. Chandel,et al. Reactive Oxygen Species Are Downstream Products of TRAF-mediated Signal Transduction* , 2001, The Journal of Biological Chemistry.
[27] A. Siddiqui,et al. Mitochondrially Associated Hepatitis B Virus X Protein Constitutively Activates Transcription Factors STAT-3 and NF-κB via Oxidative Stress , 2001, Molecular and Cellular Biology.
[28] P. Murdock,et al. Mammalian class Sigma glutathione S-transferases: catalytic properties and tissue-specific expression of human and rat GSH-dependent prostaglandin D2 synthases. , 2001, The Biochemical journal.
[29] G. Petrovics,et al. Oxidative stress induces proorphanin FQ and proenkephalin gene expression in astrocytes through p38‐ and ERK‐MAP kinases and NF‐κB , 2001 .
[30] M. Schindl,et al. DNA repair-redox enzyme apurinic endonuclease in cervical cancer: evaluation of redox control of HIF-1alpha and prognostic significance. , 2001, International journal of oncology.
[31] A. Stern,et al. Free radical-triggered hepatic injury of experimental obstructive jaundice of rats involves overproduction of proinflammatory cytokines and enhanced activation of nuclear factor kappaB. , 2001, Annals of clinical and laboratory science.
[32] J. Christman,et al. Impaired Pulmonary NF-κB Activation in Response to Lipopolysaccharide in NADPH Oxidase-Deficient Mice , 2001, Infection and Immunity.
[33] W. MacNee,et al. Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB. , 2001, Biochemical pharmacology.
[34] J. Haddad,et al. A non‐hypoxic, ROS‐sensitive pathway mediates TNF‐α‐dependent regulation of HIF‐1α , 2001 .
[35] A. Harris,et al. Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival , 2001, British Journal of Cancer.
[36] B. Ahlemeyer,et al. Preconditioning‐induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor‐κB , 2001, Journal of neurochemistry.
[37] E. Zandi,et al. Lipopolysaccharide Induces Rac1-dependent Reactive Oxygen Species Formation and Coordinates Tumor Necrosis Factor-α Secretion through IKK Regulation of NF-κB* , 2001, The Journal of Biological Chemistry.
[38] S. Reddy,et al. Activation of nuclear factor-kappa b transcriptional activity in airway epithelial cells by thioredoxin but not by N-acetyl-cysteine and glutathione. , 2001, American journal of respiratory cell and molecular biology.
[39] J. Alam,et al. Cobalt Induces Heme Oxygenase-1 Expression by a Hypoxia-inducible Factor-independent Mechanism in Chinese Hamster Ovary Cells , 2001, The Journal of Biological Chemistry.
[40] C. Pugh,et al. Hypoxia and oxidative stress in breast cancer: Hypoxia signalling pathways , 2001, Breast Cancer Research.
[41] P. Ratcliffe,et al. Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain. , 2001, Blood.
[42] J. Haddad,et al. Nuclear Factor-κB Blockade Attenuates but Does Not Abrogate Lipopolysaccharide-Dependent Tumor Necrosis Factor-α Biosynthesis in Alveolar Epithelial Cells , 2001 .
[43] M. King,et al. Oxygen Sensing and HIF-1 Activation Does Not Require an Active Mitochondrial Respiratory Chain Electron-transfer Pathway* , 2001, The Journal of Biological Chemistry.
[44] V. Hudson. Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation. , 2001, Free radical biology & medicine.
[45] A. de Bruin,et al. TNF-alpha dependent NF-kappa B activation in cultured canine keratinocytes is partly mediated by reactive oxygen species. , 2001, Veterinary dermatology.
[46] J. Haddad,et al. The biphasic immunoregulation of pyrimidylpiperazine (Y‐40138) is IL‐10 sensitive and requires NF‐κB targeting in the alveolar epithelium , 2001, British journal of pharmacology.
[47] A. Collett,et al. Oxygen‐evoked Na+ transport in rat fetal distal lung epithelial cells , 2001, The Journal of physiology.
[48] J. Haddad,et al. Alpha-melanocyte-related tripeptide, Lys-d-Pro-Val, ameliorates endotoxin-induced nuclear factor kappaB translocation and activation: evidence for involvement of an interleukin-1beta193-195 receptor antagonism in the alveolar epithelium. , 2001 .
[49] A. Collett,et al. NF-kappaB blockade reduces the O2-evoked rise in Na+ conductance in fetal alveolar cells. , 2001, Biochemical and biophysical research communications.
[50] J. Bermak,et al. Evidence for non‐oxidative dopamine cytotoxicity: potent activation of NF‐κ B and lack of protection by anti‐oxidants , 2001, Journal of neurochemistry.
[51] J. Haddad,et al. Thiol regulation of pro-inflammatory cytokines reveals a novel immunopharmacological potential of glutathione in the alveolar epithelium. , 2001, The Journal of pharmacology and experimental therapeutics.
[52] J. Haddad,et al. The ex vivo differential expression of apoptosis signaling cofactors in the developing perinatal lung: essential role of oxygenation during the transition from placental to pulmonary-based respiration. , 2001, Biochemical and biophysical research communications.
[53] B. Brüne,et al. Accumulation of HIF-1alpha under the influence of nitric oxide. , 2001, Blood.
[54] J. Yodoi,et al. An endogenous redox molecule, thioredoxin, regulates transactivation of epidermal growth factor receptor and activation of NF‐κB by lysophosphatidic acid , 2001, FEBS letters.
[55] J. Haddad,et al. CHEMIOXYEXCITATION (Δp O2/ROS)-DEPENDENT RELEASE OF IL-1β, IL-6 AND TNF-α: EVIDENCE OF CYTOKINES AS OXYGEN-SENSITIVE MEDIATORS IN THE ALVEOLAR EPITHELIUM , 2001 .
[56] W. MacNee,et al. Is oxidative stress central to the pathogenesis of chronic obstructive pulmonary disease? , 2001, Trends in molecular medicine.
[57] Z. Lee,et al. Pyrrolidine dithiocarbamate inhibits serum-induced NF-kappaB activation and induces apoptosis in ROS 17/2.8 osteoblasts. , 2001, International immunopharmacology.
[58] G. Pieper,et al. Antioxidant treatment inhibits activation of myocardial nuclear factor kappa B and inhibits nitrosylation of myocardial heme protein in cardiac transplant rejection. , 2001, Antioxidants & redox signaling.
[59] E. Ho,et al. Dietary Zinc Supplementation Inhibits NFκB Activation and Protects Against Chemically Induced Diabetes in CD1 Mice , 2001, Experimental biology and medicine.
[60] M. Fujimura,et al. SOD1 Down-Regulates NF-κB and c-Myc Expression in Mice after Transient Focal Cerebral Ischemia , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[61] L. Deng,et al. 2-Acetylaminofluorene Up-regulates Rat mdr1bExpression through Generating Reactive Oxygen Species That Activate NF-κB Pathway* , 2001, The Journal of Biological Chemistry.
[62] C. Kretz-remy,et al. Selenium: A key element that controls NF-κB activation and IκBα half life , 2001 .
[63] J. Caro,et al. Hypoxia regulation of gene transcription. , 2001, High altitude medicine & biology.
[64] S. Gebel,et al. The activity of NF-kappaB in Swiss 3T3 cells exposed to aqueous extracts of cigarette smoke is dependent on thioredoxin. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.
[65] R. Johns,et al. Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: redox-dependent effect of nitrogen oxides. , 2000, Molecular pharmacology.
[66] J. Hallenbeck,et al. Tumor Necrosis Factor and Reactive Oxygen Species Cooperative Cytotoxicity Is Mediated via Inhibition of NF-B , 2000 .
[67] F. Agani,et al. The Role of Mitochondria in the Regulation of Hypoxia-inducible Factor 1 Expression during Hypoxia* , 2000, The Journal of Biological Chemistry.
[68] J. Crapo,et al. Pulmonary immunobiology and inflammation in pulmonary diseases. , 2000, American journal of respiratory and critical care medicine.
[69] N. Fukuishi,et al. Xanthine oxidase-derived reactive oxygen species activate nuclear factor kappa B during hepatic ischemia in rats. , 2000, Japanese journal of pharmacology.
[70] W. MacNee,et al. Regulation of lipopolysaccharide-mediated interleukin-1beta release by N-acetylcysteine in THP-1 cells. , 2000, The European respiratory journal.
[71] I. Rahman. Regulation of nuclear factor-κB, activator protein-1, and glutathione levels by tumor necrosis factor-α and dexamethasone in alveolar epithelial cells , 2000 .
[72] S. Schoonbroodt,et al. Oxidative stress interference with the nuclear factor- κB activation pathways , 2000 .
[73] A. Visvikis,et al. Gamma-glutamyltranspeptidase-dependent glutathione catabolism results in activation of NF-kB. , 2000, Biochemical and biophysical research communications.
[74] C. D’Angio,et al. Oxygen regulation of gene expression: a study in opposites. , 2000, Molecular genetics and metabolism.
[75] W. MacNee,et al. Oxidative stress and regulation of glutathione in lung inflammation. , 2000, The European respiratory journal.
[76] N. Chandel,et al. Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia , 2000, The Journal of Biological Chemistry.
[77] J. Haddad,et al. Immunomodulatory potential of thymulin-Zn(2+) in the alveolar epithelium: amelioration of endotoxin-induced cytokine release and partial amplification of a cytoprotective IL-10-sensitive pathway. , 2000, Biochemical and biophysical research communications.
[78] M. Matsui,et al. Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells. , 2000, Biochemical and biophysical research communications.
[79] W. MacNee,et al. Activation of NF-κB by PM10 Occurs via an Iron-Mediated Mechanism in the Absence of IκB Degradation , 2000 .
[80] David S. McClintock,et al. Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin1 , 2000, The Journal of Immunology.
[81] J. Haddad,et al. Antioxidant/Pro-oxidant Equilibrium Regulates HIF-1α and NF-κB Redox Sensitivity , 2000, The Journal of Biological Chemistry.
[82] J. Park,et al. Cadmium blocks hypoxia-inducible factor (HIF)-1-mediated response to hypoxia by stimulating the proteasome-dependent degradation of HIF-1alpha. , 2000, European journal of biochemistry.
[83] M. Blagosklonny,et al. Carcinogenic metals induce hypoxia-inducible factor-stimulated transcription by reactive oxygen species-independent mechanism. , 2000, Cancer research.
[84] R. Shinkura,et al. Thioredoxin Inhibits Tumor Necrosis Factor- or Interleukin-1-Induced NF-κB Activation at a Level Upstream of NF-κB-Inducing Kinase , 2000 .
[85] J. Clemens,et al. Cerebral ischemia: gene activation, neuronal injury, and the protective role of antioxidants. , 2000, Free radical biology & medicine.
[86] P. Baeuerle,et al. Recent advances torwards understanding redox mechanisms in the activation of nuclear factor κb , 2000 .
[87] W. MacNee,et al. Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches. , 2000, Free radical biology & medicine.
[88] J. Haddad,et al. The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting. , 2000, Biochemical and biophysical research communications.
[89] J. J. Greene,et al. Influence of the cellular redox state on NF‐κB‐regulated gene expression , 2000 .
[90] W. MacNee,et al. Localization of gamma-glutamylcysteine synthetase messenger rna expression in lungs of smokers and patients with chronic obstructive pulmonary disease. , 2000, Free radical biology & medicine.
[91] L. Poellinger,et al. A Redox Mechanism Controls Differential DNA Binding Activities of Hypoxia-inducible Factor (HIF) 1α and the HIF-like Factor* , 2000, The Journal of Biological Chemistry.
[92] E. Ho,et al. Alpha-phenyl-tert-butylnitrone (PBN) inhibits NFkappaB activation offering protection against chemically induced diabetes. , 2000, Free radical biology & medicine.
[93] L. Poellinger,et al. Redox-Regulated Recruitment of the Transcriptional Coactivators CREB-Binding Protein and SRC-1 to Hypoxia-Inducible Factor 1α , 2000, Molecular and Cellular Biology.
[94] H. Nakamura,et al. Redox regulation by thioredoxin superfamily; protection against oxidative stress and aging , 2000, Free radical research.
[95] J. Christman,et al. Redox Regulation of Nuclear Factor Kappa B: Therapeutic Potential for Attenuating Inflammatory Responses , 2000, Brain pathology.
[96] J. Christman,et al. Oxidative Stress and NF-κB Activation: Correlation in Patients Following Allogeneic Bone Marrow Transplantation , 2000 .
[97] A. Bowie,et al. Oxidative stress and nuclear factor-kappaB activation: a reassessment of the evidence in the light of recent discoveries. , 2000, Biochemical pharmacology.
[98] R. Vanacore,et al. Role for copper in transient oxidation and nuclear translocation of MTF-1, but not of NF-kappa B, by the heme-hemopexin transport system. , 2000, Antioxidants & redox signaling.
[99] J. Haddad,et al. Glutathione depletion is associated with augmenting a proinflammatory signal: evidence for an antioxidant/pro-oxidant mechanism regulating cytokines in the alveolar epithelium. , 2000, Cytokines, cellular & molecular therapy.
[100] E. Ho,et al. Antioxidants, NFκB Activation, and Diabetogenesis , 1999 .
[101] A. Baba,et al. Apoptosis in Ca2 + reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF‐κB activation , 1999, The European journal of neuroscience.
[102] G. Semenza,et al. Protection from Oxidative Stress–Induced Apoptosis in Cortical Neuronal Cultures by Iron Chelators Is Associated with Enhanced DNA Binding of Hypoxia-Inducible Factor-1 and ATF-1/CREB and Increased Expression of Glycolytic Enzymes, p21waf1/cip1, and Erythropoietin , 1999, The Journal of Neuroscience.
[103] J. Mazière,et al. Cellular enrichment with polyunsaturated fatty acids induces an oxidative stress and activates the transcription factors AP1 and NFkappaB. , 1999, Biochemical and biophysical research communications.
[104] H. Wiśniewski,et al. Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice. , 1999, Brain research. Molecular brain research.
[105] W. MacNee,et al. Oxidants and antioxidants as therapeutic targets in chronic obstructive pulmonary disease. , 1999, American journal of respiratory and critical care medicine.
[106] Ze'ev Ronai,et al. Role of redox potential and reactive oxygen species in stress signaling , 1999, Oncogene.
[107] K. Knudtson,et al. The p38 mitogen-activated protein kinase is required for NF-kappaB-dependent gene expression. The role of TATA-binding protein (TBP). , 1999, The Journal of biological chemistry.
[108] B. Huchzermeyer,et al. Involvement of reactive oxygen species in TNF-α mediated activation of the transcription factor NF-κB in canine dermal fibroblasts , 1999 .
[109] J. Hayes,et al. Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. , 1999, Free radical research.
[110] E. Ho,et al. Supplementation of N‐acetylcysteine inhibits NFκB activation and protects against alloxan‐induced diabetes in CD‐1 mice , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[111] K. Mori,et al. Distinct Roles of Thioredoxin in the Cytoplasm and in the Nucleus , 1999, The Journal of Biological Chemistry.
[112] J. Finkelstein,et al. Antioxidant treatment attenuates cytokine and chemokine levels in murine macrophages following silica exposure. , 1999, Toxicology and applied pharmacology.
[113] S. Manna,et al. Overexpression of γ-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1 , 1999, Oncogene.
[114] J. Caro,et al. Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins. , 1999, Biochemical and biophysical research communications.
[115] B. Wallaert,et al. Thiol regulation of the production of TNF-α, IL-6 and IL-8 by human alveolar macrophages , 1999 .
[116] D. Gius,et al. Intracellular oxidation/reduction status in the regulation of transcription factors NF-kappaB and AP-1. , 1999, Toxicology letters.
[117] I. Macara,et al. Cooperativity between Oxidants and Tumor Necrosis Factor in the Activation of Nuclear Factor (NF)- κ B , 1999 .
[118] Y. Fujii‐Kuriyama,et al. Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: their stabilization and redox signal‐induced interaction with CBP/p300 , 1999, The EMBO journal.
[119] J. Sweatt,et al. Mitochondria Mediate Tumor Necrosis Factor-α/NF-κB Signaling in Skeletal Muscle Myotubes , 1999 .
[120] W. MacNee,et al. Molecular Mechanism of the Regulation of Glutathione Synthesis by Tumor Necrosis Factor-α and Dexamethasone in Human Alveolar Epithelial Cells* , 1999, The Journal of Biological Chemistry.
[121] W. MacNee,et al. Epithelial permeability, inflammation, and oxidant stress in the air spaces of smokers. , 1999, American journal of respiratory and critical care medicine.
[122] M. Ueffing,et al. Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-κB , 1999, Oncogene.
[123] Kawashima,et al. Effects of bucillamine and N‐acetyl‐ L‐cysteine on cytokine production and collagen‐induced arthritis (CIA) , 1999, Clinical and experimental immunology.
[124] C. Sen,et al. Nuclear factor kappa B activity in response to oxidants and antioxidants. , 1999, Methods in enzymology.
[125] C. McClain,et al. Treatment with glutathione precursor decreases cytokine activity. , 1999, JPEN. Journal of parenteral and enteral nutrition.
[126] B. Aggarwal,et al. Antioxidants differentially regulate activation of nuclear factor-kappa B, activator protein-1, c-jun amino-terminal kinases, and apoptosis induced by tumor necrosis factor: evidence that JNK and NF-kappa B activation are not linked to apoptosis. , 1999, Antioxidants & redox signaling.
[127] I. Rahman,et al. Inflammation and the regulation of glutathione level in lung epithelial cells. , 1999, Antioxidants & redox signaling.
[128] K. Sumikawa,et al. Glutathione Downregulates the Phosphorylation of IκB: Autoloop Regulation of the NF-κB-Mediated Expression of NF-κB Subunits by TNF-α in Mouse Vascular Endothelial Cells , 1998 .
[129] K. Roebuck,et al. H2O2 and Tumor Necrosis Factor-α Induce Differential Binding of the Redox-responsive Transcription Factors AP-1 and NF-κB to the Interleukin-8 Promoter in Endothelial and Epithelial Cells* , 1998, The Journal of Biological Chemistry.
[130] G. Burckart,et al. Nuclear Factor Kappa B: Important Transcription Factor and Therapeutic Target , 1998, Journal of clinical pharmacology.
[131] T. Kawai,et al. Glutathione depletion inhibits oxidant-induced activation of nuclear factor-kappa B, AP-1, and c-Jun/ATF-2 in cultured guinea-pig gastric epithelial cells , 1998, Journal of Gastroenterology.
[132] M. Ginn-Pease,et al. Redox Signals and NF-κB Activation in T Cells , 1998 .
[133] J. Caro,et al. Hypoxia-inducible factor 1alpha (HIF-1alpha) is a non-heme iron protein. Implications for oxygen sensing. , 1998, The Journal of biological chemistry.
[134] J. Piette,et al. Impairment of the mitochondrial electron chain transport prevents NF-kappa B activation by hydrogen peroxide. , 1998, Free radical biology & medicine.
[135] W. MacNee,et al. Role of transcription factors in inflammatory lung diseases , 1998, Thorax.
[136] L. Oberley,et al. Redox gene therapy for ischemia/reperfusion injury of the liver reduces AP1 and NF-κB activation , 1998, Nature Medicine.
[137] C. Sen. Redox signaling and the emerging therapeutic potential of thiol antioxidants. , 1998, Biochemical pharmacology.
[138] G. Stiles,et al. Oxidative stress increases A1 adenosine receptor expression by activating nuclear factor kappa B. , 1998, Molecular pharmacology.
[139] L. Huang,et al. Erythropoietin: a model system for studying oxygen-dependent gene regulation. , 1998, The Journal of experimental biology.
[140] P. Ratcliffe,et al. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. , 1998, The Journal of experimental biology.
[141] J. Reimund,et al. Antioxidants inhibit the in vitro production of inflammatory cytokines in Crohn's disease and ulcerative colitis , 1998, European journal of clinical investigation.
[142] H. Forman,et al. Transmembrane Redox Signaling Activates NF-κB in Macrophages , 1998 .
[143] K. Jeang,et al. Regulatory Role for a Novel Human Thioredoxin Peroxidase in NF-κB Activation* , 1997, The Journal of Biological Chemistry.
[144] O. Saugstad,et al. Bronchopulmonary dysplasia and oxidative stress: are we closer to an understanding of the pathogenesis of BPD? , 1997, Acta paediatrica.
[145] R. Brigelius-Flohé,et al. Thiol modulation inhibits the interleukin (IL)‐1‐mediated activation of an IL‐1 receptor‐associated protein kinase and NF‐xB , 1997, European journal of immunology.
[146] J. Caro,et al. Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes. , 1997, The Journal of biological chemistry.
[147] J. Piette,et al. Involvement of different transduction pathways in NF-kappa B activation by several inducers. , 1997, Free radical research.
[148] W. MacNee,et al. Free radical activity of industrial fibers: role of iron in oxidative stress and activation of transcription factors. , 1997, Environmental health perspectives.
[149] David M. Rothwarf,et al. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB , 1997, Nature.
[150] H. Forman,et al. Increased transcription of the regulatory subunit of gamma-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion. , 1997, Archives of biochemistry and biophysics.
[151] H. Kamata,et al. Redox regulation of lipopolysaccharide (LPS)-induced interleukin-8 (IL-8) gene expression mediated by NF kappa B and AP-1 in human astrocytoma U373 cells. , 1997, Biochemical and biophysical research communications.
[152] B. Rovin,et al. Modulation of IL-1-induced chemokine expression in human mesangial cells through alterations in redox status. , 1997, Cytokine.
[153] E. Muñoz,et al. Cellular redox status influences both cytotoxic and NF‐κB activation in natural killer cells , 1997, Immunology.
[154] Y. Rojanasakul,et al. One-Electron Reduction of Chromium(VI) by α-Lipoic Acid and Related Hydroxyl Radical Generation, dG Hydroxylation and Nuclear Transcription Factor-κB Activation , 1997 .
[155] J. Piette,et al. Activation of the NF-kappaB transcription factor in a T-lymphocytic cell line by hypochlorous acid. , 1997, The Biochemical journal.
[156] S. Sakurada,et al. Regulation of NF-kappa B and disease control: identification of a novel serine kinase and thioredoxin as effectors for signal transduction pathway for NF-kappa B activation. , 1997, Current topics in cellular regulation.
[157] K. Schulze-Osthoff,et al. Oxidative stress and signal transduction. , 1997, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.
[158] T. Russo,et al. Gene regulation by reactive oxygen species. , 1997, Current topics in cellular regulation.
[159] C. Sen,et al. Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription. , 1997, Advances in pharmacology.
[160] L. Packer,et al. Redox regulation of NF-kappa B activation. , 1997, Free radical biology & medicine.
[161] W. MacNee,et al. Transcriptional regulation of gamma-glutamylcysteine synthetase-heavy subunit by oxidants in human alveolar epithelial cells. , 1996, Biochemical and biophysical research communications.
[162] E. S. Fox,et al. Thiol regulation of endotoxin-induced release of tumour necrosis factor alpha from isolated rat Kupffer cells. , 1996, The Biochemical journal.
[163] D. Livingston,et al. Activation of Hypoxia-inducible Transcription Factor Depends Primarily upon Redox-sensitive Stabilization of Its α Subunit* , 1996, The Journal of Biological Chemistry.
[164] R. O. Poyton,et al. Oxygen sensing and molecular adaptation to hypoxia. , 1996, Physiological reviews.
[165] C. Sen,et al. Antioxidant and redox regulation of gene transcription , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[166] J. J. Greene,et al. Cooperation of protein disulfide isomerase and redox environment in the regulation of NF‐κB and AP1 binding to DNA , 1996, Cell biochemistry and function.
[167] L. O’Neill,et al. Inhibition of NF kappa B activity by oxidative processes in intact cells mechanism of action of pyrolidine dithiocarbamate and diamide. , 1996, Biochemical Society transactions.
[168] Y. Sun,et al. Redox regulation of transcriptional activators. , 1996, Free radical biology & medicine.
[169] P. Sigler,et al. Structure of NF-κB p50 homodimer bound to a κB site , 1998, Nature.
[170] J. Bonnefoy,et al. Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis , 1995, The Journal of experimental medicine.
[171] N. Kaplowitz,et al. Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kappa B: studies with isolated mitochondria and rat hepatocytes. , 1995, Molecular pharmacology.
[172] K. Schulze-Osthoff,et al. Redox signalling by transcription factors NF-κB and AP-1 in lymphocytes , 1995 .
[173] R. Hay,et al. Regulation of the DNA binding activity of NF-κB , 1995 .
[174] G. Semenza,et al. Effect of altered redox states on expression and DNA-binding activity of hypoxia-inducible factor 1. , 1995, Biochemical and biophysical research communications.
[175] L. Packer,et al. Redox regulation of NF-kappa B DNA binding activity by dihydrolipoate. , 1995, Biochemistry and molecular biology international.
[176] Jeffrey R. Huth,et al. Solution structure of human thioredoxin in a mixed disulfide intermediate complex with its target peptide from the transcription factor NFκB , 1995 .
[177] J. Piette,et al. NF-kappa B transcription factor and human immunodeficiency virus type 1 (HIV-1) activation by methylene blue photosensitization. , 1995, European journal of biochemistry.
[178] J. Remacle,et al. Low levels of reactive oxygen species as modulators of cell function. , 1995, Mutation research.
[179] K. Schulze-Osthoff,et al. HIV‐1 Tat potentiates TNF‐induced NF‐kappa B activation and cytotoxicity by altering the cellular redox state. , 1995, The EMBO journal.
[180] Gregory L. Verdine,et al. Structure of the NF-κB p50 homodimer bound to DNA , 1995, Nature.
[181] F. Staal,et al. [17] Redox regulation of activation of NF-κB transcription factor complex: Effects of N-acetylcysteine , 1995 .
[182] D. Romberger,et al. Immunological functions of the pulmonary epithelium. , 1995, The European respiratory journal.
[183] L. Packer,et al. Redox regulation of DNA-protein interactions by biothiols. , 1995, Methods in enzymology.
[184] F. Staal,et al. Separation of oxidant-initiated and redox-regulated steps in the NF-kappa B signal transduction pathway. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[185] K. Schulze-Osthoff,et al. Functions of glutathione and glutathione disulfide in immunology and immunopathology , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[186] Yamamoto Ken-ichi,et al. Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro , 1994 .
[187] H. Pahl,et al. Regulation of the transcription factors NF-kappa B and AP-1 by redox changes. , 1994, Chemico-biological interactions.
[188] W. Dröge,et al. Distinct effects of glutathione disulphide on the nuclear transcription factor kappa B and the activator protein-1. , 1994, European journal of biochemistry.
[189] P. Baeuerle,et al. [14] Assessing oxygen radicals as mediators in activation of inducible eukaryotic transcription factor NF-κB , 1994 .
[190] Y. Tan,et al. Differential induction of nuclear NF-kappa B by protein phosphatase inhibitors in primary and transformed human cells. Requirement for both oxidation and phosphorylation in nuclear translocation. , 1993, The Journal of biological chemistry.
[191] R. Crystal,et al. Systemic deficiency of glutathione in cystic fibrosis. , 1993, Journal of applied physiology.
[192] E. Pacht,et al. Oxidized glutathione is increased in the alveolar fluid of patients with the adult respiratory distress syndrome. , 1993, The American review of respiratory disease.
[193] L. O’Neill,et al. Evidence for a redox-sensitive protein tyrosine kinase in nuclear factor kappa B activation and interleukin 2 production in EL4.NOB1 cells. , 1993, Biochemical Society transactions.
[194] L. Nicod,et al. Cytokines. 1. Overview. , 1993, Thorax.
[195] A. Baldwin,et al. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation , 1993, Molecular and cellular biology.
[196] T. Okamoto,et al. Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin. , 1993, The Journal of biological chemistry.
[197] Timothy N. C. Wells,et al. Role of cysteine62 in DNA recognition by the P50 subunit of NF-xB , 1993 .
[198] B. Aggarwal,et al. α-Lipoic acid is a potent inhibitor of NF-κB activation in human T cells , 1992 .
[199] F. Aillet,et al. Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines. , 1992, Journal of immunology.
[200] J. Yodoi,et al. Thiordoxin regulates the DNA binding activity of NF-χB by reduction of a disulphid bond involving cysteine 62 , 1992 .
[201] D. Männel,et al. Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells , 1992, The Journal of experimental medicine.
[202] G. Bernard,et al. N-acetylcysteine in experimental and clinical acute lung injury. , 1991, The American journal of medicine.
[203] W. Leonard,et al. Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[204] G. Cohen,et al. Potentiation of the cell specific toxicity of paraquat by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Implications for the heterogeneous distribution of glutathione (GSH) in rat lung. , 1990, Biochemical pharmacology.
[205] R. Crystal,et al. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. , 1989, The American review of respiratory disease.
[206] O. Aruoma,et al. The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, superoxide, and hypochlorous acid. , 1989, Free radical biology & medicine.
[207] A. Meister. Glutathione metabolism and its selective modification. , 1988, The Journal of biological chemistry.
[208] David Baltimore,et al. Multiple nuclear factors interact with the immunoglobulin enhancer sequences , 1986, Cell.
[209] A. Meister,et al. Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine). , 1979, The Journal of biological chemistry.