Allele specific Taqman-based real-time PCR assay to quantify circulating BRAFV600E mutated DNA in plasma of melanoma patients.

[1]  K. Nathanson.  Using genetics and genomics strategies to personalize therapy for cancer: focus on melanoma. , 2010, Biochemical pharmacology.

[2]  A. Bosserhoff,et al.  Recent progress in understanding the pathology of malignant melanoma , 2009, The Journal of pathology.

[3]  V. Beneš,et al.  The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. , 2009, Clinical chemistry.

[4]  L. Čabrijan,et al.  Molecular and genetic mechanisms in melanoma. , 2008, Collegium antropologicum.

[5]  F. Cianchi,et al.  High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer. , 2008, American journal of clinical pathology.

[6]  M. Kolodney,et al.  Selective amplification of rare mutations using locked nucleic acid oligonucleotides that competitively inhibit primer binding to wild-type DNA. , 2008, The Journal of investigative dermatology.

[7]  M. Pierotti,et al.  Detection of mutated BRAFV600E variant in circulating DNA of stage III–IV melanoma patients , 2007, International journal of cancer.

[8]  C. Pratilas,et al.  Therapeutic strategies for targeting BRAF in human cancer. , 2007, Reviews on recent clinical trials.

[9]  D. Polsky,et al.  Detection of mutant BRAF alleles in the plasma of patients with metastatic melanoma. , 2007, The Journal of molecular diagnostics : JMD.

[10]  S. O’Day,et al.  Utility of Circulating B-RAF DNA Mutation in Serum for Monitoring Melanoma Patients Receiving Biochemotherapy , 2007, Clinical Cancer Research.

[11]  N. Thomas.  BRAF somatic mutations in malignant melanoma and melanocytic naevi , 2006, Melanoma research.

[12]  P. Khavari,et al.  Melanoma genetics and the development of rational therapeutics. , 2005, The Journal of clinical investigation.

[13]  D. Polsky,et al.  Clinical significance of BRAF mutations in metastatic melanoma , 2004, Journal of Translational Medicine.

[14]  J. Durocher,et al.  High Sensitivity Scanning of Colorectal Tumors and Matched Plasma DNA for Mutations in APC, TP53, K‐RAS, and BRAF Genes with a Novel DHPLC Fluorescence Detection Platform , 2004, Annals of the New York Academy of Sciences.

[15]  K. K. Vdovichenko,et al.  Mutant Form of BRAF Gene in Blood Plasma of Cancer Patients , 2004, Annals of the New York Academy of Sciences.

[16]  D. Morton,et al.  Incidence of BRAF Oncogene Mutation and Clinical Relevance for Primary Cutaneous Melanomas , 2004, Clinical Cancer Research.

[17]  C. Goessl.  Diagnostic potential of circulating nucleic acids for oncology , 2003, Expert review of molecular diagnostics.

[18]  K. Smalley,et al.  A pivotal role for ERK in the oncogenic behaviour of malignant melanoma? , 2003, International journal of cancer.

[19]  D. Elder,et al.  Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation. , 2003, Cancer research.

[20]  A. Nicholson,et al.  Mutations of the BRAF gene in human cancer , 2002, Nature.

[21]  C. Peyssonnaux,et al.  The Raf/MEK/ERK pathway: new concepts of activation , 2001, Biology of the cell.

[22]  G. Sorenson,et al.  Detection of mutated KRAS2 sequences as tumor markers in plasma/serum of patients with gastrointestinal cancer. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

[23]  U. Lehmann,et al.  Detection of gene amplification in archival breast cancer specimens by laser-assisted microdissection and quantitative real-time polymerase chain reaction. , 2000, The American journal of pathology.

[24]  C. Marshall,et al.  Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases* , 1997, The Journal of Biological Chemistry.

[25]  P. J. Pretorius,et al.  Is the role of circulating DNA as a biomarker of cancer being prematurely overrated? , 2010, Clinical biochemistry.

[26]  M. Fleischhacker,et al.  Circulating nucleic acids (CNAs) and cancer--a survey. , 2007, Biochimica et biophysica acta.

[27]  P. Meltzer,et al.  High frequency of BRAF mutations in nevi , 2003, Nature Genetics.