Controlled Trial of Oxethazaine as an Analgesic in Duodenal Ulcer

barbitone, quinalbarbitone, and butobarbitone drops to 70% for phenobarbitone and cyclobarbitone it is approximately 50%. Mercury barbitone is relatively soluble in water, and the method is less sensitive for barbitone. This is convenient because considerably higher blood levels of barbitone are necessary to account for coma than for the shorter-acting barbiturates. Glutethimide (" doriden ") and bemegride (" megimide") react in the same way as the barbiturates at approximately the same concentrations. Now that thin-layer chromatography can be used for the separation of barbiturates (Sunshine, Rose, and LeBeau, 1963), identification and assay are within the ability of any hospital laboratory, and the probable time the patient will remain in coma, if infection does not supervene, can be assessed (Curry, l 963b). Summay Barbiturate concentrations in 1 ml. of blood can now be assessed in a little over five minutes without recourse even to a colorimeter.