Generation and Application of Transgenic Rabbits

[1]  J. Brunt Molecular Farming: Transgenic Animals as Bioreactors , 1988, Bio/Technology.

[2]  G. Brem,et al.  Detection of homozygous individuals in gene transfer experiments by semiquantitative PCR. , 1995, BioTechniques.

[3]  G. Brem,et al.  Intracellular, genetic or congenital immunisation--transgenic approaches to increase disease resistance of farm animals. , 1996, Journal of biotechnology.

[4]  G. Brem,et al.  Mammary gland specific expression of chymosin constructs in transgenic rabbits , 1995 .

[5]  R. Palmiter,et al.  Germline and somatic mosaicism in transgenic mice. , 1986, Developmental biology.

[6]  R. Passey,et al.  The genes encoding the major milk-specific proteins and their use in transgenic studies and protein engineering. , 1994, Biotechnology & genetic engineering reviews.

[7]  G. Brem,et al.  Laparoscopic embryo transfer in rabbits. , 1993, Journal of reproduction and fertility.

[8]  J. Taylor,et al.  Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[9]  J. Logan Transgenic animals: beyond 'funny milk'. , 1993, Current opinion in biotechnology.

[10]  L. Chan,et al.  Transgenic rabbits with the integrated human 15‐lipoxygenase gene driven by a lysozyme promoter: macrophage‐specific expression and variable positional specificity of the transgenic enzyme , 1995, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  G. Brem,et al.  Production of foreign proteins in the mammary glands of transgenic mammals , 1993 .

[12]  C. E. Adams,et al.  The development of rabbit eggs after culture in vitro for 1-4 days. , 1970, Journal of embryology and experimental morphology.

[13]  K. Bürki,et al.  Rabbit β-Casein Promoter Directs Secretion of Human Interleukin-2 into the Milk of Transgenic Rabbits , 1990, Bio/Technology.

[14]  H. Lenz,et al.  Genes encoding a mouse monoclonal antibody are expressed in transgenic mice, rabbits and pigs. , 1991, Gene.

[15]  M. Mehtali,et al.  Human immunodeficiency virus type 1 infection of human CD4-transgenic rabbits. , 1995, The Journal of general virology.

[16]  E. Wolf,et al.  Expression of synthetic cDNA sequences encoding human insulin-like growth factor-1 (IGF-1) in the mammary gland of transgenic rabbits. , 1994, Gene.

[17]  G. Brem,et al.  A mammary-specific promoter directs expression of growth hormone not only to the mammary gland, but also to Bergman glia cells in transgenic mice. , 1991, Molecular endocrinology.

[18]  J. de la Fuente,et al.  Transgenic rabbits as bioreactors for the production of human growth hormone. , 1995, Journal of biotechnology.

[19]  J. Fuente,et al.  Secretion of human erythropoetin by mammary gland explants from lactating transgenic rabbits , 1995 .

[20]  G. Brem,et al.  Transgenic strategies to increase disease resistance in livestock. , 1994, Reproduction, fertility, and development.

[21]  S. Damak,et al.  Improved Wool Production in Transgenic Sheep Expressing Insulin-like Growth Factor 1 , 1996, Bio/Technology.

[22]  E. Southern Detection of specific sequences among DNA fragments separated by gel electrophoresis. , 1975, Journal of molecular biology.

[23]  R. Palmiter,et al.  Expression of mouse IgA by transgenic mice, pigs and sheep , 1991, European journal of immunology.

[24]  Thomas J. White,et al.  PCR protocols: a guide to methods and applications. , 1990 .

[25]  R. Palmiter,et al.  Introns increase transcriptional efficiency in transgenic mice. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[26]  E. Wolf,et al.  Multiple consequences of human growth hormone expression in transgenic mice. , 1989, Molecular biology & medicine.

[27]  R. Palmiter,et al.  Production of transgenic rabbits, sheep and pigs by microinjection , 1985, Nature.

[28]  L. Houdebine Production of pharmaceutical proteins by transgenic animals , 2008, Comparative Immunology, Microbiology and Infectious Diseases.

[29]  J. Isner,et al.  Time course of recombinant protein secretion after liposome-mediated gene transfer in a rabbit arterial organ culture model. , 1994, Laboratory investigation; a journal of technical methods and pathology.

[30]  J. Taylor,et al.  Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[31]  R. Moreadith,et al.  Derivation and characterization of putative pluripotential embryonic stem cells from preimplantation rabbit embryos , 1993, Molecular reproduction and development.

[32]  W. Whitten Exploiting New Technologies in Animal Breeding , 1991 .

[33]  G. Brem,et al.  YAC transgenesis in farm animals: Rescue of albinism in rabbits , 1996, Molecular reproduction and development.

[34]  G. Brem Inheritance and tissue‐specific expression of transgenes in rabbits and pigs , 1993, Molecular reproduction and development.

[35]  B. Davidson,et al.  Inhibition of interleukin-1-induced effects in synoviocytes transduced with the human IL-1 receptor antagonist cDNA using an adenoviral vector. , 1995, Human gene therapy.

[36]  J. Wilson,et al.  In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. , 1994, The Journal of biological chemistry.

[37]  R. Lathe,et al.  Pharmaceuticals from transgenic livestock , 1987 .

[38]  H. Abderrahim,et al.  Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs , 1994, Nature Genetics.

[39]  C. Tunyaplin,et al.  Lymphoid and non-lymphoid tumors in E kappa-myc transgenic rabbits. , 1994, Leukemia.

[40]  B. Groner,et al.  Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[41]  D. McManus,et al.  Nucleic acids: vaccines of the future. , 1995, Parasitology today.

[42]  G. Brem,et al.  Attempts to Produce Transgenic Rabbits Carrying MTI-HGH Recombinant Gene , 1988 .

[43]  E. Winnacker,et al.  Production of transgenic mice, rabbits and pigs by microinjection into pronuclei , 1985 .

[44]  J. Rosen,et al.  Tissue-specific expression of the rat β-casein gene in transgenic mice , 1988 .

[45]  E. Lacy,et al.  Bovine AlphaS1-Casein Gene Sequences Direct High Level Expression of Active Human Urokinase in Mouse Milk , 1990, Bio/Technology.

[46]  R. Foote,et al.  Improved development of rabbit one-cell embryos to the hatching blastocyst stage by culture in a defined, protein-free culture medium. , 1991, Journal of reproduction and fertility.

[47]  M. Perricaudet,et al.  Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector. , 1994, Circulation.

[48]  E. Hummler,et al.  Tyrosinase as a marker for transgenic mice. , 1991, Nucleic acids research.

[49]  R. Krauss,et al.  Overexpression of human apolipoprotein B-100 in transgenic rabbits results in increased levels of LDL and decreased levels of HDL. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[50]  E. Kawasaki 18 – SAMPLE PREPARATION FROM BLOOD, CELLS, AND OTHER FLUIDS , 1990 .

[51]  J. Kreider,et al.  Papillomas and carcinomas in transgenic rabbits carrying EJ-ras DNA and cottontail rabbit papillomavirus DNA , 1993, Journal of virology.

[52]  R. Mulligan,et al.  The basic science of gene therapy. , 1993, Science.

[53]  M. Baranyi,et al.  New data on the proteins of rabbit (Oryctolagus cuniculus) milk. , 1995, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

[54]  R. Palmiter,et al.  Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[55]  J. Robl,et al.  Effect of milking frequency oh collection of milk from nursing New Zealand white rabbits 1 , 1993 .

[56]  L. Hennighausen,et al.  The mammary gland as a bioreactor: production of foreign proteins in milk. , 1990, Protein expression and purification.

[57]  L. Hennighausen,et al.  Production of Human Tissue Plasminogen Activator in Transgenic Mouse Milk , 1987, Bio/Technology.

[58]  R. Foote,et al.  Nuclear transfer of putative rabbit embryonic stem cells leads to normal blastocyst development. , 1995, Journal of reproduction and fertility.

[59]  J. Kreider,et al.  Methylation of cottontail rabbit papillomavirus DNA and tissue-specific expression in transgenic rabbits. , 1995, Virus research.

[60]  L. Hennighausen The prospects for domesticating milk protein genes , 1992, Journal of cellular biochemistry.

[61]  D. Huszar,et al.  Antigen-specific human antibodies from mice comprising four distinct genetic modifications , 1994, Nature.

[62]  T. Kindt,et al.  HIV-1 mediates rapid apoptosis of lymphocytes from human CD4 transgenic but not normal rabbits. , 1995, Virology.

[63]  G. Brem,et al.  A fast detection protocol for screening large numbers of transgenic animals. , 1989, Nucleic acids research.

[64]  M. I. Prokof'ev,et al.  Transgenic rabbits with antisense RNA gene targeted at adenovirus H5 , 1991 .

[65]  R. F. Hoyt,et al.  Lecithin:Cholesterol Acyltransferase Overexpression Generates Hyperalpha-lipoproteinemia and a Nonatherogenic Lipoprotein Pattern in Transgenic Rabbits (*) , 1996, The Journal of Biological Chemistry.

[66]  R. Jaenisch,et al.  A generic intron increases gene expression in transgenic mice , 1991, Molecular and cellular biology.

[67]  R. Wall Transgenic livestock: Progress and prospects for the future , 1996 .

[68]  N. Yang,et al.  In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[69]  K. Rajewsky,et al.  Cre-loxP-mediated gene replacement: a mouse strain producing humanized antibodies , 1994, Current Biology.

[70]  F. Bosch,et al.  Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice. , 1990, The EMBO journal.

[71]  E. Wolf,et al.  The GH-transgenic mouse as an experimental model for growth research: clinical and pathological studies. , 1992, Hormone research.

[72]  K. Mullis,et al.  Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. , 1988, Science.

[73]  V. Oi,et al.  Transgenic rabbits with lymphocytic leukemia induced by the c-myc oncogene fused with the immunoglobulin heavy chain enhancer. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[74]  Anton C. Beynen,et al.  New Developments in Biosciences: Their Implications for Laboratory Animal Science , 1988, Springer Netherlands.

[75]  J. de la Fuente,et al.  Production of transgenic mice and rabbits that carry and express the human tissue plasminogen activator cDNA under the control of a bovine alpha S1 casein promoter. , 1993, Theriogenology.

[76]  Michael G. Rosenfeld,et al.  Dramatic growth of mice that develop from eggs microinjected with metallothionein–growth hormone fusion genes , 1982, Nature.

[77]  R. Palmiter,et al.  Heterologous introns can enhance expression of transgenes in mice. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[78]  T. Kindt,et al.  Developmental and tissue‐specific expression of human CD4 in transgenic rabbits , 1995, Molecular reproduction and development.

[79]  J. Brunt In China, the Dragon Searches for the Pearl , 1988, Bio/Technology.