Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forces

[1]  J. Merzaban,et al.  Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs , 2007, Nature Immunology.

[2]  U. V. von Andrian,et al.  CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo , 2007, The Journal of experimental medicine.

[3]  Michael Loran Dustin,et al.  Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. , 2007, Immunity.

[4]  M. Shimaoka,et al.  Importance of force linkage in mechanochemistry of adhesion receptors. , 2006, Biochemistry.

[5]  Ronald N Germain,et al.  Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. , 2006, Immunity.

[6]  Klaus Schulten,et al.  How the headpiece hinge angle is opened: new insights into the dynamics of integrin activation , 2006, The Journal of cell biology.

[7]  R. Alon,et al.  DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration. , 2006, Blood.

[8]  M. Krummel,et al.  Surface-bound chemokines capture and prime T cells for synapse formation , 2006, Nature Immunology.

[9]  D. Irvine,et al.  Homeostatic Lymphoid Chemokines Synergize with Adhesion Ligands to Trigger T and B Lymphocyte Chemokinesis1 , 2006, The Journal of Immunology.

[10]  Grégory Giannone,et al.  Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. , 2006, Trends in cell biology.

[11]  M. Sheetz,et al.  Local force and geometry sensing regulate cell functions , 2006, Nature Reviews Molecular Cell Biology.

[12]  Michael P. Sheetz,et al.  Rigidity Sensing at the Leading Edge through αvβ3 Integrins and RPTPα , 2006 .

[13]  S. Bromley,et al.  Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics , 2005, Nature Immunology.

[14]  A. Trautmann,et al.  CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen , 2005, The Journal of Immunology.

[15]  E. Butcher,et al.  Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues , 2005, Nature Immunology.

[16]  T. Kinashi,et al.  Intracellular signalling controlling integrin activation in lymphocytes , 2005, Nature Reviews Immunology.

[17]  J. Xu,et al.  Neutrophil microtubules suppress polarity and enhance directional migration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[18]  Mark J. Miller,et al.  Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells , 2005, PLoS biology.

[19]  Antonio Lanzavecchia,et al.  T cell costimulation by chemokine receptors , 2005, Nature Immunology.

[20]  Waldemar Kolanus,et al.  Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines , 2005, Nature Immunology.

[21]  A. Gebert,et al.  Naive, Effector, and Memory T Lymphocytes Efficiently Scan Dendritic Cells In Vivo: Contact Frequency in T Cell Zones of Secondary Lymphoid Organs Does Not Depend on LFA-1 Expression and Facilitates Survival of Effector T Cells1 , 2005, The Journal of Immunology.

[22]  Michael Sixt,et al.  The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. , 2005, Immunity.

[23]  T. Hara,et al.  Lymph Node Fibroblastic Reticular Cells Construct the Stromal Reticulum via Contact with Lymphocytes , 2004, The Journal of experimental medicine.

[24]  Michael Loran Dustin.  Stop and go traffic to tune T cell responses. , 2004, Immunity.

[25]  T. Kohout,et al.  Differential Desensitization, Receptor Phosphorylation, β-Arrestin Recruitment, and ERK1/2 Activation by the Two Endogenous Ligands for the CC Chemokine Receptor 7* , 2004, Journal of Biological Chemistry.

[26]  D. Webb,et al.  Talin: an emerging focal point of adhesion dynamics. , 2004, Current opinion in cell biology.

[27]  S. Henrickson,et al.  T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases , 2004, Nature.

[28]  E. Scarpini,et al.  RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. , 2004, Immunity.

[29]  G. Belz,et al.  Most lymphoid organ dendritic cell types are phenotypically and functionally immature. , 2003, Blood.

[30]  Joanna C. Porter,et al.  LFA-1-induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment , 2003, Journal of Cell Science.

[31]  D. Schlaepfer,et al.  Paxillin Binding to the α4 Integrin Subunit Stimulates LFA-1 (Integrin αLβ2)-Dependent T Cell Migration by Augmenting the Activation of Focal Adhesion Kinase/Proline-Rich Tyrosine Kinase-21 , 2003, The Journal of Immunology.

[32]  V. Niggli.  Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways , 2003, Journal of Cell Science.

[33]  Mark J. Miller,et al.  Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[34]  D. Schlaepfer,et al.  Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2. , 2003, Journal of immunology.

[35]  S. Bromley,et al.  Stimulation of naïve T‐cell adhesion and immunological synapse formation by chemokine‐dependent and ‐independent mechanisms , 2002, Immunology.

[36]  J. Cyster,et al.  Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid Neogenesis1 , 2002, The Journal of Immunology.

[37]  D. Olive,et al.  Role of ICAM-3 in the initial interaction of T lymphocytes and APCs , 2002, Nature Immunology.

[38]  D. Kucik,et al.  The Microtubule Cytoskeleton Participates in Control of β2 Integrin Avidity* , 2001, The Journal of Biological Chemistry.

[39]  L. Piccio,et al.  Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. , 2000, Immunity.

[40]  Amnon Peled,et al.  Subsecond Induction of α4 Integrin Clustering by Immobilized Chemokines Stimulates Leukocyte Tethering and Rolling on Endothelial Vascular Cell Adhesion Molecule 1 under Flow Conditions , 2000, The Journal of experimental medicine.

[41]  S. Bromley,et al.  Cutting Edge: Hierarchy of Chemokine Receptor and TCR Signals Regulating T Cell Migration and Proliferation1 , 2000, The Journal of Immunology.

[42]  U. V. von Andrian,et al.  The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules , 2000, The Journal of experimental medicine.

[43]  E. Wolf,et al.  CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs , 1999, Cell.

[44]  R. Snyderman,et al.  Regulation of Human Chemokine Receptors CXCR4 , 1997, The Journal of Biological Chemistry.

[45]  Wei Wang,et al.  A new class of membrane-bound chemokine with a CX3C motif , 1997, Nature.

[46]  Daniel Choquet,et al.  Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages , 1997, Cell.

[47]  F. Sallusto,et al.  Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha , 1994, The Journal of experimental medicine.

[48]  J. Merzaban,et al.  Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs , 2007, Nature Immunology.

[49]  U. V. von Andrian,et al.  CCR7 ligands stimulate the intranodal motility of T lymphocytes in vivo , 2007, The Journal of experimental medicine.

[50]  J. Cyster,et al.  CC Chemokine Receptor 7 Contributes to Gi-Dependent T Cell Motility in the Lymph Node1 , 2007, The Journal of Immunology.

[51]  Michael Loran Dustin,et al.  Force as a facilitator of integrin conformational changes during leukocyte arrest on blood vessels and antigen-presenting cells. , 2007, Immunity.

[52]  M. Shimaoka,et al.  Importance of force linkage in mechanochemistry of adhesion receptors. , 2006, Biochemistry.

[53]  Ronald N Germain,et al.  Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. , 2006, Immunity.

[54]  Klaus Schulten,et al.  How the headpiece hinge angle is opened: new insights into the dynamics of integrin activation , 2006, The Journal of cell biology.

[55]  R. Alon,et al.  DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration. , 2006, Blood.

[56]  M. Krummel,et al.  Surface-bound chemokines capture and prime T cells for synapse formation , 2006, Nature Immunology.

[57]  D. Irvine,et al.  Homeostatic Lymphoid Chemokines Synergize with Adhesion Ligands to Trigger T and B Lymphocyte Chemokinesis1 , 2006, The Journal of Immunology.

[58]  Grégory Giannone,et al.  Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. , 2006, Trends in cell biology.

[59]  M. Sheetz,et al.  Local force and geometry sensing regulate cell functions , 2006, Nature Reviews Molecular Cell Biology.

[60]  Michael P. Sheetz,et al.  Rigidity Sensing at the Leading Edge through αvβ3 Integrins and RPTPα , 2006 .

[61]  S. Bromley,et al.  Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics , 2005, Nature Immunology.

[62]  A. Trautmann,et al.  CC Chemokine Ligand 19 Secreted by Mature Dendritic Cells Increases Naive T Cell Scanning Behavior and Their Response to Rare Cognate Antigen , 2005, The Journal of Immunology.

[63]  E. Butcher,et al.  Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues , 2005, Nature Immunology.

[64]  T. Kinashi,et al.  Intracellular signalling controlling integrin activation in lymphocytes , 2005, Nature Reviews Immunology.

[65]  J. Xu,et al.  Neutrophil microtubules suppress polarity and enhance directional migration. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[66]  Mark J. Miller,et al.  Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells , 2005, PLoS biology.

[67]  Antonio Lanzavecchia,et al.  T cell costimulation by chemokine receptors , 2005, Nature Immunology.

[68]  Waldemar Kolanus,et al.  Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines , 2005, Nature Immunology.

[69]  A. Gebert,et al.  Naive, Effector, and Memory T Lymphocytes Efficiently Scan Dendritic Cells In Vivo: Contact Frequency in T Cell Zones of Secondary Lymphoid Organs Does Not Depend on LFA-1 Expression and Facilitates Survival of Effector T Cells1 , 2005, The Journal of Immunology.

[70]  Michael Sixt,et al.  The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. , 2005, Immunity.

[71]  T. Hara,et al.  Lymph Node Fibroblastic Reticular Cells Construct the Stromal Reticulum via Contact with Lymphocytes , 2004, The Journal of experimental medicine.

[72]  Michael Loran Dustin.  Stop and go traffic to tune T cell responses. , 2004, Immunity.

[73]  T. Kohout,et al.  Differential Desensitization, Receptor Phosphorylation, β-Arrestin Recruitment, and ERK1/2 Activation by the Two Endogenous Ligands for the CC Chemokine Receptor 7* , 2004, Journal of Biological Chemistry.

[74]  D. Webb,et al.  Talin: an emerging focal point of adhesion dynamics. , 2004, Current opinion in cell biology.

[75]  S. Henrickson,et al.  T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases , 2004, Nature.

[76]  E. Scarpini,et al.  RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. , 2004, Immunity.

[77]  G. Belz,et al.  Most lymphoid organ dendritic cell types are phenotypically and functionally immature. , 2003, Blood.

[78]  Joanna C. Porter,et al.  LFA-1-induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment , 2003, Journal of Cell Science.

[79]  D. Schlaepfer,et al.  Paxillin Binding to the α4 Integrin Subunit Stimulates LFA-1 (Integrin αLβ2)-Dependent T Cell Migration by Augmenting the Activation of Focal Adhesion Kinase/Proline-Rich Tyrosine Kinase-21 , 2003, The Journal of Immunology.

[80]  V. Niggli.  Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways , 2003, Journal of Cell Science.

[81]  Mark J. Miller,et al.  Autonomous T cell trafficking examined in vivo with intravital two-photon microscopy , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[82]  S. Bromley,et al.  Stimulation of naïve T‐cell adhesion and immunological synapse formation by chemokine‐dependent and ‐independent mechanisms , 2002, Immunology.

[83]  J. Cyster,et al.  Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid Neogenesis1 , 2002, The Journal of Immunology.

[84]  D. Olive,et al.  Role of ICAM-3 in the initial interaction of T lymphocytes and APCs , 2002, Nature Immunology.

[85]  D. Kucik,et al.  The Microtubule Cytoskeleton Participates in Control of β2 Integrin Avidity* , 2001, The Journal of Biological Chemistry.

[86]  L. Piccio,et al.  Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. , 2000, Immunity.

[87]  S. Bromley,et al.  Cutting Edge: Hierarchy of Chemokine Receptor and TCR Signals Regulating T Cell Migration and Proliferation1 , 2000, The Journal of Immunology.

[88]  U. V. von Andrian,et al.  The Cc Chemokine Thymus-Derived Chemotactic Agent 4 (Tca-4, Secondary Lymphoid Tissue Chemokine, 6ckine, Exodus-2) Triggers Lymphocyte Function–Associated Antigen 1–Mediated Arrest of Rolling T Lymphocytes in Peripheral Lymph Node High Endothelial Venules , 2000, The Journal of experimental medicine.

[89]  E. Wolf,et al.  CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs , 1999, Cell.

[90]  R. Snyderman,et al.  Regulation of Human Chemokine Receptors CXCR4 , 1997, The Journal of Biological Chemistry.

[91]  Wei Wang,et al.  A new class of membrane-bound chemokine with a CX3C motif , 1997, Nature.

[92]  Daniel Choquet,et al.  Extracellular Matrix Rigidity Causes Strengthening of Integrin–Cytoskeleton Linkages , 1997, Cell.

[93]  F. Sallusto,et al.  Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha , 1994, The Journal of experimental medicine.