The transition to compulsion in addiction

[1]  R. Palmiter,et al.  Synergy of Distinct Dopamine Projection Populations in Behavioral Reinforcement , 2019, Neuron.

[2]  Junya Hirokawa,et al.  Frontal cortex neuron types categorically encode single decision variables , 2019, Nature.

[3]  K. Tye,et al.  A cortical-brainstem circuit predicts and governs compulsive alcohol drinking , 2019, Science.

[4]  Kevin T. Beier,et al.  Complementary Genetic Targeting and Monosynaptic Input Mapping Reveal Recruitment and Refinement of Distributed Corticostriatal Ensembles by Cocaine , 2019, Neuron.

[5]  C. Lüscher,et al.  Cortico-striatal synaptic plasticity underlying compulsive reward seeking , 2019, bioRxiv.

[6]  Tengfei Ma,et al.  Optogenetic control of alcohol-seeking behavior via the dorsomedial striatal circuit , 2019, Neuropharmacology.

[7]  G. Urcelay,et al.  Delayed rewards facilitate habit formation. , 2019, Journal of experimental psychology. Animal learning and cognition.

[8]  K. Kendrick,et al.  Cue Reactivity in the Ventral Striatum Characterizes Heavy Cannabis Use, Whereas Reactivity in the Dorsal Striatum Mediates Dependent Use. , 2019, Biological psychiatry. Cognitive neuroscience and neuroimaging.

[9]  A. Haith,et al.  Time-dependent competition between goal-directed and habitual response preparation , 2019, Nature Human Behaviour.

[10]  C. Gaveriaux-Ruff,et al.  Mu opioid receptors in the medial habenula contribute to naloxone aversion , 2019, Neuropsychopharmacology.

[11]  H. Gu,et al.  Compulsive drug use is associated with imbalance of orbitofrontal- and prelimbic-striatal circuits in punishment-resistant individuals , 2019, Proceedings of the National Academy of Sciences.

[12]  B. Everitt,et al.  Compulsive Alcohol Seeking Results from a Failure to Disengage Dorsolateral Striatal Control over Behavior , 2019, The Journal of Neuroscience.

[13]  T. Robbins,et al.  Goal-Directed and Habitual Control in Smokers , 2019, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

[14]  S. Duan,et al.  Cannabinoid CB1 receptors in the amygdalar cholecystokinin glutamatergic afferents to nucleus accumbens modulate depressive-like behavior , 2019, Nature Medicine.

[15]  Masaya Harada,et al.  Stochastic synaptic plasticity underlying compulsion in a model of addiction , 2018, Nature.

[16]  C. Lüscher,et al.  Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement , 2018, bioRxiv.

[17]  L. Hogarth,et al.  Intact goal‐directed control in treatment‐seeking drug users indexed by outcome‐devaluation and Pavlovian to instrumental transfer: critique of habit theory , 2018, The European journal of neuroscience.

[18]  Bernard W. Balleine,et al.  The Bilateral Prefronto-striatal Pathway Is Necessary for Learning New Goal-Directed Actions , 2018, Current Biology.

[19]  Shauna L. Parkes,et al.  Insular and Ventrolateral Orbitofrontal Cortices Differentially Contribute to Goal-Directed Behavior in Rodents , 2018, Cerebral cortex.

[20]  A. Nimmerjahn,et al.  Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors , 2018, Science.

[21]  S. Farris,et al.  A molecular mechanism for choosing alcohol over an alternative reward , 2018, Science.

[22]  E. Murray,et al.  Specializations for reward-guided decision-making in the primate ventral prefrontal cortex , 2018, Nature Reviews Neuroscience.

[23]  Yvette C. van Dongen,et al.  Mesencephalic dopamine neurons interfacing the shell of nucleus accumbens and the dorsolateral striatum in the rat , 2018, Journal of neuroscience research.

[24]  K. Wassum,et al.  Regulation of habit formation in the dorsal striatum , 2018, Current Opinion in Behavioral Sciences.

[25]  B. Everitt,et al.  Heroin seeking becomes dependent on dorsal striatal dopaminergic mechanisms and can be decreased by N‐acetylcysteine , 2018, The European journal of neuroscience.

[26]  Fengyu Liu,et al.  Hypersensitivity of Prelimbic Cortex Neurons Contributes to Aggravated Nociceptive Responses in Rats With Experience of Chronic Inflammatory Pain , 2018, Front. Mol. Neurosci..

[27]  T. Robbins,et al.  Methylphenidate modifies the motion of the circadian clock Lamotrigine in mood disorders and cocaine dependence Cortical glutamate in postpartum depression Evidence for a long-lasting compulsive alcohol seeking phenotype in rats , 2017 .

[28]  S. Lammel,et al.  Nucleus Accumbens Subnuclei Regulate Motivated Behavior via Direct Inhibition and Disinhibition of VTA Dopamine Subpopulations , 2018, Neuron.

[29]  T. Robinson,et al.  Are Cocaine-Seeking “Habits” Necessary for the Development of Addiction-Like Behavior in Rats? , 2017, The Journal of Neuroscience.

[30]  Serge H. Ahmed.  Trying to make sense of rodents' drug choice behavior , 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[31]  Rachel J. Smith,et al.  Behavioral and neural mechanisms underlying habitual and compulsive drug seeking , 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[32]  Nathan J. Marchant,et al.  Punishment of alcohol-reinforced responding in alcohol preferring P rats reveals a bimodal population: Implications for models of compulsive drug seeking , 2017, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[33]  C. Gremel,et al.  Chronic alcohol exposure disrupts top-down control over basal ganglia action selection to produce habits , 2018, Nature Communications.

[34]  D. Lovinger,et al.  Alcohol and the Brain: Neuronal Molecular Targets, Synapses, and Circuits , 2017, Neuron.

[35]  J. Cadet,et al.  Compulsive methamphetamine taking under punishment is associated with greater cue-induced drug seeking in rats , 2017, Behavioural Brain Research.

[36]  C. Lupica,et al.  Lateral Habenula Involvement in Impulsive Cocaine Seeking , 2017, Neuropsychopharmacology.

[37]  M. Botvinick,et al.  The successor representation in human reinforcement learning , 2016, bioRxiv.

[38]  D. Martínez,et al.  Blunted Dopamine Transmission in Addiction: Potential Mechanisms and Implications for Behavior. , 2017, Seminars in nuclear medicine.

[39]  Allison N. Kurti,et al.  A review of the literature on contingency management in the treatment of substance use disorders, 2009-2014. , 2016, Preventive medicine.

[40]  Michele Pignatelli,et al.  Antagonistic negative and positive neurons of the basolateral amygdala , 2016, Nature Neuroscience.

[41]  T. Robinson,et al.  Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior , 2016, Psychopharmacology.

[42]  N. Volkow,et al.  Neurobiology of addiction: a neurocircuitry analysis. , 2016, The lancet. Psychiatry.

[43]  Guy B. Williams,et al.  Carrots and sticks fail to change behavior in cocaine addiction , 2016, Science.

[44]  K. Deisseroth,et al.  Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation , 2016, Neuron.

[45]  C. Lüscher,et al.  Cell-Type Specific Insertion of GluA2-Lacking AMPARs with Cocaine Exposure Leading to Sensitization, Cue-Induced Seeking, and Incubation of Craving , 2016, Neuropsychopharmacology.

[46]  M. Wolf.  Synaptic mechanisms underlying persistent cocaine craving , 2016, Nature Reviews Neuroscience.

[47]  Yingjie Zhu,et al.  A thalamic input to the nucleus accumbens mediates opiate dependence , 2016, Nature.

[48]  R. Wise,et al.  Lateral hypothalamic circuits for feeding and reward , 2016, Nature Neuroscience.

[49]  A. Bonci,et al.  Transcranial magnetic stimulation of dorsolateral prefrontal cortex reduces cocaine use: A pilot study , 2016, European Neuropsychopharmacology.

[50]  T. Robbins,et al.  Drug Addiction: Updating Actions to Habits to Compulsions Ten Years On. , 2016, Annual review of psychology.

[51]  Wendy Wood,et al.  Psychology of Habit. , 2016, Annual review of psychology.

[52]  B. Everitt,et al.  In search of predictive endophenotypes in addiction: insights from preclinical research , 2016, Genes, brain, and behavior.

[53]  Y. Shaham,et al.  Animal models of drug relapse and craving: From drug priming-induced reinstatement to incubation of craving after voluntary abstinence. , 2016, Progress in brain research.

[54]  Laura A. Bradfield,et al.  Medial Orbitofrontal Cortex Mediates Outcome Retrieval in Partially Observable Task Situations , 2015, Neuron.

[55]  B. Everitt,et al.  Basolateral and central amygdala differentially recruit and maintain dorsolateral striatum-dependent cocaine-seeking habits , 2015, Nature Communications.

[56]  C. Lüscher,et al.  Sufficiency of Mesolimbic Dopamine Neuron Stimulation for the Progression to Addiction , 2015, Neuron.

[57]  Sharon Morein-Zamir,et al.  Fronto-striatal circuits in response-inhibition: Relevance to addiction , 2015, Brain Research.

[58]  David Erritzoe,et al.  The dopamine theory of addiction: 40 years of highs and lows , 2015, Nature Reviews Neuroscience.

[59]  N. Schmitzer-Torbert,et al.  Post-training cocaine administration facilitates habit learning and requires the infralimbic cortex and dorsolateral striatum , 2015, Neurobiology of Learning and Memory.

[60]  P. Dayan,et al.  Disorders of compulsivity: a common bias towards learning habits , 2014, Molecular Psychiatry.

[61]  B. Everitt.  Neural and psychological mechanisms underlying compulsive drug seeking habits and drug memories – indications for novel treatments of addiction* , 2014, The European journal of neuroscience.

[62]  N. Volkow,et al.  Stimulant-induced dopamine increases are markedly blunted in active cocaine abusers , 2014, Molecular Psychiatry.

[63]  C. Lüscher,et al.  Contrasting forms of cocaine-evoked plasticity control components of relapse , 2014, Nature.

[64]  A. Goodchild,et al.  Behavioral and Neural Substrates of Habit Formation in Rats Intravenously Self-Administering Nicotine , 2014, Neuropsychopharmacology.

[65]  T. Robbins,et al.  Behavioral and neuroimaging evidence for overreliance on habit learning in alcohol-dependent patients , 2013, Translational Psychiatry.

[66]  T. Robbins,et al.  Neuroscience and Biobehavioral Reviews Review from the Ventral to the Dorsal Striatum: Devolving Views of Their Roles in Drug Addiction , 2022 .

[67]  Kelly R. Tan,et al.  Cocaine Disinhibits Dopamine Neurons by Potentiation of GABA Transmission in the Ventral Tegmental Area , 2013, Science.

[68]  C. Baunez,et al.  Deep brain stimulation for addiction: why the subthalamic nucleus should be favored , 2013, Current Opinion in Neurobiology.

[69]  G. Koob.  Negative reinforcement in drug addiction: the darkness within , 2013, Current Opinion in Neurobiology.

[70]  B. Everitt,et al.  Addiction: failure of control over maladaptive incentive habits , 2013, Current Opinion in Neurobiology.

[71]  A. Bonci,et al.  Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake , 2013, Nature Neuroscience.

[72]  Guy B. Williams,et al.  Meta-analysis of structural brain abnormalities associated with stimulant drug dependence and neuroimaging of addiction vulnerability and resilience , 2013, Current Opinion in Neurobiology.

[73]  Kyle S. Smith,et al.  A Dual Operator View of Habitual Behavior Reflecting Cortical and Striatal Dynamics , 2013, Neuron.

[74]  B. Everitt,et al.  Differential roles of the prefrontal cortical subregions and basolateral amygdala in compulsive cocaine seeking and relapse after voluntary abstinence in rats , 2013, The European journal of neuroscience.

[75]  F. Woodward Hopf,et al.  Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking , 2013, Nature.

[76]  B. Balleine,et al.  Associative learning mechanisms underpinning the transition from recreational drug use to addiction , 2013, Annals of the New York Academy of Sciences.

[77]  B. Everitt,et al.  Hierarchical recruitment of phasic dopamine signaling in the striatum during the progression of cocaine use , 2012, Proceedings of the National Academy of Sciences.

[78]  L. Vanderschuren,et al.  Compulsive drug use and its neural substrates , 2012, Reviews in the neurosciences.

[79]  Kyle S. Smith,et al.  Reversible online control of habitual behavior by optogenetic perturbation of medial prefrontal cortex , 2012, Proceedings of the National Academy of Sciences.

[80]  D. van der Kooy,et al.  The neurobiology of opiate motivation. , 2012, Cold Spring Harbor perspectives in medicine.

[81]  P. Janak,et al.  Habitual Alcohol Seeking: Time Course and the Contribution of Subregions of the Dorsal Striatum , 2012, Biological Psychiatry.

[82]  K. Deisseroth,et al.  Input-specific control of reward and aversion in the ventral tegmental area , 2012, Nature.

[83]  B. Everitt,et al.  Double Dissociation of the Dorsomedial and Dorsolateral Striatal Control Over the Acquisition and Performance of Cocaine Seeking , 2012, Neuropsychopharmacology.

[84]  B. Everitt,et al.  Differential Roles of the Dorsolateral and Midlateral Striatum in Punished Cocaine Seeking , 2012, The Journal of Neuroscience.

[85]  B. Everitt,et al.  Drug Intake is Sufficient, but Conditioning is not Necessary for the Emergence of Compulsive Cocaine Seeking After Extended Self-Administration , 2012, Neuropsychopharmacology.

[86]  Guy B. Williams,et al.  Abnormal Brain Structure Implicated in Stimulant Drug Addiction , 2012, Science.

[87]  B. Balleine,et al.  Amygdala Central Nucleus Interacts with Dorsolateral Striatum to Regulate the Acquisition of Habits , 2012, The Journal of Neuroscience.

[88]  C. Lüscher,et al.  Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour , 2011, Nature.

[89]  B. Balleine,et al.  Annals of the New York Academy of Sciences the Orbitofrontal Cortex, Predicted Value, and Choice , 2022 .

[90]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[91]  B. Balleine,et al.  The General and Outcome-Specific Forms of Pavlovian-Instrumental Transfer Are Differentially Mediated by the Nucleus Accumbens Core and Shell , 2011, The Journal of Neuroscience.

[92]  Y. Shaham,et al.  Neurobiology of the incubation of drug craving , 2011, Trends in Neurosciences.

[93]  D. Lovinger,et al.  Synaptic and Morphological Neuroadaptations in the Putamen Associated with Long-Term, Relapsing Alcohol Drinking in Primates , 2011, Neuropsychopharmacology.

[94]  T. Robbins,et al.  Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence , 2011, Brain : a journal of neurology.

[95]  K. Deisseroth,et al.  Drug-Driven AMPA Receptor Redistribution Mimicked by Selective Dopamine Neuron Stimulation , 2010, PloS one.

[96]  A. Zapata,et al.  Shift from Goal-Directed to Habitual Cocaine Seeking after Prolonged Experience in Rats , 2010, The Journal of Neuroscience.

[97]  P. Holland,et al.  The central amygdala projection to the substantia nigra reflects prediction error information in appetitive conditioning. , 2010, Learning & memory.

[98]  Karl Mann,et al.  Initial, habitual and compulsive alcohol use is characterized by a shift of cue processing from ventral to dorsal striatum. , 2010, Addiction.

[99]  Serge H. Ahmed,et al.  Cocaine Is Low on the Value Ladder of Rats: Possible Evidence for Resilience to Addiction , 2010, PloS one.

[100]  A. Dickinson,et al.  Choice and contingency in the development of behavioral autonomy during instrumental conditioning. , 2010, Journal of experimental psychology. Animal behavior processes.

[101]  P. Piazza,et al.  Transition to Addiction Is Associated with a Persistent Impairment in Synaptic Plasticity , 2010, Science.

[102]  R. Hampson,et al.  Effects of cocaine rewards on neural representations of cognitive demand in nonhuman primates , 2010, Psychopharmacology.

[103]  B. Balleine,et al.  Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action , 2010, Neuropsychopharmacology.

[104]  G. Koob.  Neurobiological substrates for the dark side of compulsivity in addiction , 2009, Neuropharmacology.

[105]  R. Spanagel,et al.  RESEARCH FOCUS ON COMPULSIVE BEHAVIOUR IN ANIMALS: Compulsive alcohol drinking in rodents , 2009, Addiction biology.

[106]  P. Kalivas.  The glutamate homeostasis hypothesis of addiction , 2009, Nature Reviews Neuroscience.

[107]  C. Lüscher,et al.  Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc , 2009, Nature Neuroscience.

[108]  P. Piazza,et al.  Pattern of Intake and Drug Craving Predict the Development of Cocaine Addiction-like Behavior in Rats , 2009, Biological Psychiatry.

[109]  B. Balleine,et al.  The integrative function of the basal ganglia in instrumental conditioning , 2009, Behavioural Brain Research.

[110]  G. Koob.  New dimensions in human laboratory models of addiction , 2009, Addiction biology.

[111]  B. Balleine,et al.  On habits and addiction: An associative analysis of compulsive drug seeking. , 2008, Drug discovery today. Disease models.

[112]  R. Costa,et al.  High on Habits , 2008, Front. Neurosci..

[113]  D. Nutt,et al.  Brain dopamine response in human opioid addiction , 2008, British Journal of Psychiatry.

[114]  Trevor W. Robbins,et al.  High Impulsivity Predicts the Switch to Compulsive Cocaine-Taking , 2008, Science.

[115]  B. Balleine,et al.  Differential Involvement of the Basolateral Amygdala and Mediodorsal Thalamus in Instrumental Action Selection , 2008, The Journal of Neuroscience.

[116]  B. Everitt,et al.  Cocaine Seeking Habits Depend upon Dopamine-Dependent Serial Connectivity Linking the Ventral with the Dorsal Striatum , 2008, Neuron.

[117]  Geoffrey Schoenbaum,et al.  The Role of Orbitofrontal Cortex in Drug Addiction: A Review of Preclinical Studies , 2008, Biological Psychiatry.

[118]  T. Robbins,et al.  Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement , 2008, Psychopharmacology.

[119]  S. Ikemoto.  Dopamine reward circuitry: Two projection systems from the ventral midbrain to the nucleus accumbens–olfactory tubercle complex , 2007, Brain Research Reviews.

[120]  O. Hikosaka,et al.  Lateral habenula as a source of negative reward signals in dopamine neurons , 2007, Nature.

[121]  Barry J. Everitt,et al.  Compulsive drug seeking by rats under punishment: effects of drug taking history , 2007, Psychopharmacology.

[122]  D. Belin,et al.  Cocaine-induced sensitization is associated with altered dynamics of transcriptional responses of the dopamine transporter, tyrosine hydroxylase, and dopamine D2 receptors in C57Bl/6J mice , 2007, Psychopharmacology.

[123]  P. Holland,et al.  Dissociable effects of disconnecting amygdala central nucleus from the ventral tegmental area or substantia nigra on learned orienting and incentive motivation , 2007, The European journal of neuroscience.

[124]  H. Damasio,et al.  Damage to the Insula Disrupts Addiction to Cigarette Smoking , 2007, Science.

[125]  P. Mahadevan,et al.  An overview , 2007, Journal of Biosciences.

[126]  Alain Dagher,et al.  Modeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men. , 2006, Archives of general psychiatry.

[127]  C. Lüscher,et al.  The Mechanistic Classification of Addictive Drugs , 2006, PLoS medicine.

[128]  Monique Ernst,et al.  Increased Occupancy of Dopamine Receptors in Human Striatum during Cue-Elicited Cocaine Craving , 2006, Neuropsychopharmacology.

[129]  R. Wise.  Role of brain dopamine in food reward and reinforcement , 2006, Philosophical Transactions of the Royal Society B: Biological Sciences.

[130]  N. Volkow,et al.  Cocaine Cues and Dopamine in Dorsal Striatum: Mechanism of Craving in Cocaine Addiction , 2006, The Journal of Neuroscience.

[131]  S. Killcross,et al.  Amphetamine Exposure Enhances Habit Formation , 2006, The Journal of Neuroscience.

[132]  P. Kalivas,et al.  Homer Isoforms Differentially Regulate Cocaine-Induced Neuroplasticity , 2006, Neuropsychopharmacology.

[133]  R. Spanagel,et al.  REVIEW: Behavioural assessment of drug reinforcement and addictive features in rodents: an overview , 2006, Addiction biology.

[134]  T. Robbins,et al.  Erratum: Neural systems of reinforcement for drug addition: from actions to habits to compulsion , 2006, Nature Neuroscience.

[135]  B. Balleine.  Neural bases of food-seeking: Affect, arousal and reward in corticostriatolimbic circuits , 2005, Physiology & Behavior.

[136]  T. Robbins,et al.  Neural systems of reinforcement for drug addiction: from actions to habits to compulsion , 2005, Nature Neuroscience.

[137]  B. Everitt,et al.  Involvement of the Dorsal Striatum in Cue-Controlled Cocaine Seeking , 2005, The Journal of Neuroscience.

[138]  Drake Morgan,et al.  Reduced Dopamine Terminal Function and Insensitivity to Cocaine Following Cocaine Binge Self-Administration and Deprivation , 2005, Neuropsychopharmacology.

[139]  B. Balleine,et al.  The role of the dorsomedial striatum in instrumental conditioning , 2005, The European journal of neuroscience.

[140]  T. Robinson,et al.  Opposite effects of amphetamine self-administration experience on dendritic spines in the medial and orbital prefrontal cortex. , 2004, Cerebral cortex.

[141]  T. Robbins,et al.  Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement , 1996, Psychopharmacology.

[142]  R. Cardinal,et al.  Nucleus accumbens core lesions retard instrumental learning and performance with delayed reinforcement in the rat , 2005, BMC Neuroscience.

[143]  G. Koob,et al.  Enhanced alcohol self-administration after intermittent versus continuous alcohol vapor exposure. , 2004, Alcoholism, clinical and experimental research.

[144]  B. Everitt,et al.  Drug Seeking Becomes Compulsive After Prolonged Cocaine Self-Administration , 2004, Science.

[145]  David Belin,et al.  Evidence for Addiction-like Behavior in the Rat , 2004, Science.

[146]  B. Everitt,et al.  Direct Interactions between the Basolateral Amygdala and Nucleus Accumbens Core Underlie Cocaine-Seeking Behavior by Rats , 2004, The Journal of Neuroscience.

[147]  P. Holland.  Relations between Pavlovian-instrumental transfer and reinforcer devaluation. , 2004, Journal of experimental psychology. Animal behavior processes.

[148]  T. Robbins,et al.  Differential control over cocaine-seeking behavior by nucleus accumbens core and shell , 2004, Nature Neuroscience.

[149]  S. Higgins,et al.  Clinical implications of reinforcement as a determinant of substance use disorders. , 2004, Annual review of psychology.

[150]  B. Balleine,et al.  Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning , 2004, The European journal of neuroscience.

[151]  Manfred Malzahn.  The darkness within , 2004 .

[152]  F. Bloom,et al.  Destruction of dopamine in the nucleus accumbens selectively attenuates cocaine but not heroin self-administration in rats , 2004, Psychopharmacology.

[153]  F. Bloom,et al.  Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems , 2004, Psychopharmacology.

[154]  Athina Markou,et al.  Increased motivation for self-administered cocaine after escalated cocaine intake , 2003, Neuroreport.

[155]  A. Dickinson,et al.  Oral cocaine seeking by rats: action or habit? , 2003, Behavioral neuroscience.

[156]  B. Everitt,et al.  The contribution of the amygdala, nucleus accumbens, and prefrontal cortex to emotion and motivated behaviour , 2003 .

[157]  S. Killcross,et al.  Coordination of actions and habits in the medial prefrontal cortex of rats. , 2003, Cerebral cortex.

[158]  P. Kalivas,et al.  Brain circuitry and the reinstatement of cocaine-seeking behavior , 2003, Psychopharmacology.

[159]  R. Malenka,et al.  Drugs of Abuse and Stress Trigger a Common Synaptic Adaptation in Dopamine Neurons , 2003, Neuron.

[160]  A. Dickinson,et al.  Alcohol Seeking by Rats: Action or Habit? , 2002, The Quarterly journal of experimental psychology. B, Comparative and physiological psychology.

[161]  Rita Z. Goldstein,et al.  Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. , 2002, The American journal of psychiatry.

[162]  T. Robbins,et al.  Dopamine Release in the Dorsal Striatum during Cocaine-Seeking Behavior under the Control of a Drug-Associated Cue , 2002, The Journal of Neuroscience.

[163]  K. Berridge,et al.  The Neuroscience of Natural Rewards: Relevance to Addictive Drugs , 2002, The Journal of Neuroscience.

[164]  B. Everitt,et al.  Emotion and motivation: the role of the amygdala, ventral striatum, and prefrontal cortex , 2002, Neuroscience & Biobehavioral Reviews.

[165]  Steven W Anderson,et al.  Decision-making deficits, linked to a dysfunctional ventromedial prefrontal cortex, revealed in alcohol and stimulant abusers , 2001, Neuropsychologia.

[166]  P. Kalivas,et al.  The Circuitry Mediating Cocaine-Induced Reinstatement of Drug-Seeking Behavior , 2001, The Journal of Neuroscience.

[167]  Bruce T. Hope,et al.  Neuroadaptation: Incubation of cocaine craving after withdrawal , 2001, Nature.

[168]  Mark A. Ungless,et al.  Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons , 2001, Nature.

[169]  A. Dickinson,et al.  Cocaine seeking by rats is a goal-directed action. , 2001, Behavioral neuroscience.

[170]  Trevor W Robbins,et al.  Investigating the neurocognitive deficits associated with chronic drug misuse , 2001, Current Opinion in Neurobiology.

[171]  G. Koob,et al.  Drug Addiction, Dysregulation of Reward, and Allostasis , 2001, Neuropsychopharmacology.

[172]  T. Robbins,et al.  Second-order schedules of drug reinforcement in rats and monkeys: measurement of reinforcing efficacy and drug-seeking behaviour , 2000, Psychopharmacology.

[173]  A. Dickinson,et al.  Cocaine-seeking by rats: regulation, reinforcement and activation , 2000, Psychopharmacology.

[174]  Nikolaus R. McFarland,et al.  Striatonigrostriatal Pathways in Primates Form an Ascending Spiral from the Shell to the Dorsolateral Striatum , 2000, The Journal of Neuroscience.

[175]  C. Baird,et al.  The pilot study. , 2000, Orthopedic nursing.

[176]  J S Fowler,et al.  Addiction, a disease of compulsion and drive: involvement of the orbitofrontal cortex. , 2000, Cerebral cortex.

[177]  K. Miczek,et al.  Cocaine self-administration ”binges”: transition from behavioral and autonomic regulation toward homeostatic dysregulation in rats , 2000, Psychopharmacology.

[178]  S. H. Ahmed,et al.  Long-lasting increase in the set point for cocaine self-administration after escalation in rats , 1999, Psychopharmacology.

[179]  T. Robbins,et al.  Dissociable Deficits in the Decision-Making Cognition of Chronic Amphetamine Abusers, Opiate Abusers, Patients with Focal Damage to Prefrontal Cortex, and Tryptophan-Depleted Normal Volunteers: Evidence for Monoaminergic Mechanisms , 1999, Neuropsychopharmacology.

[180]  T. Robbins,et al.  Dissociation in Effects of Lesions of the Nucleus Accumbens Core and Shell on Appetitive Pavlovian Approach Behavior and the Potentiation of Conditioned Reinforcement and Locomotor Activity byd-Amphetamine , 1999, The Journal of Neuroscience.

[181]  G F Koob,et al.  Transition from moderate to excessive drug intake: change in hedonic set point. , 1998, Science.

[182]  Ronald C. Kessler,et al.  Comparative epidemiology of dependence on tobacco, alcohol, controlled substances, and inhalants: Basic findings from the National Comorbidity Survey. , 1994 .

[183]  R. Kessler,et al.  Comparative Epidemiology of Dependence on Tobacco , Alcohol , Controlled Substances , and Inhalants : Basic Findings From the National Comorbidity Survey , 1994 .

[184]  Athina Markou,et al.  Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration , 1992, Brain Research.

[185]  R. North,et al.  Opioids excite dopamine neurons by hyperpolarization of local interneurons , 1992, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[186]  J. Wolffgramm.  An ethopharmacological approach to the development of drug addiction , 1991, Neuroscience and Biobehavioral Reviews.

[187]  T. Robbins,et al.  Involvement of the amygdala in stimulus-reward associations: Interaction with the ventral striatum , 1989, Neuroscience.

[188]  G. Di Chiara,et al.  Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[189]  R. Rescorla,et al.  Associative Structures In Instrumental Learning , 1986 .

[190]  A. Dickinson.  Actions and habits: the development of behavioural autonomy , 1985 .

[191]  A. Dickinson.  Conditioning and associative learning. , 1981, British medical bulletin.

[192]  C. Brewer.  Alcohol and the brain. , 1976, Nursing times.

[193]  S. Goldberg.  Comparable behavior maintained under fixed-ratio and second-order schedules of food presentation, cocaine injection or d-amphetamine injection in the squirrel monkey. , 1973, The Journal of pharmacology and experimental therapeutics.

[194]  J. R. Weeks,et al.  Experimental Morphine Addiction: Method for Automatic Intravenous Injections in Unrestrained Rats , 1962, Science.