Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

[1]  J. Chambers,et al.  The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids* , 2003, The Journal of Biological Chemistry.

[2]  Masataka Harada,et al.  A G Protein-coupled Receptor Responsive to Bile Acids* , 2003, The Journal of Biological Chemistry.

[3]  R. Curi,et al.  Pleiotropic effects of fatty acids on pancreatic β‐cells , 2003 .

[4]  R. Bergman,et al.  Free Fatty Acids and Pathogenesis of Type 2 Diabetes Mellitus , 2000, Trends in Endocrinology & Metabolism.

[5]  J. Henquin,et al.  Triggering and amplifying pathways of regulation of insulin secretion by glucose. , 2000, Diabetes.

[6]  O. Nishimura,et al.  Identification of Neuromedin U as the Cognate Ligand of the Orphan G Protein-coupled Receptor FM-3* , 2000, The Journal of Biological Chemistry.

[7]  M. Ezekowitz Atrial Fibrillation: The Epidemic of the New Millennium , 1999, Annals of Internal Medicine.

[8]  S. Hinuma,et al.  The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors , 1999, Journal of Molecular Medicine.

[9]  L. Jovanovič,et al.  Type 2 diabetes: the epidemic of the new millennium. , 1999, Annals of clinical and laboratory science.

[10]  J. Gutkind,et al.  Cell growth control by G protein-coupled receptors: from signal transduction to signal integration , 1998, Oncogene.

[11]  J. McGarry,et al.  A fatty acid- dependent step is critically important for both glucose- and non-glucose-stimulated insulin secretion. , 1998, The Journal of clinical investigation.

[12]  Hirokazu Matsumoto,et al.  A prolactin-releasing peptide in the brain , 1998, Nature.

[13]  L. F. Kolakowski,et al.  A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1. , 1997, Biochemical and biophysical research communications.

[14]  E. Nunez Biological complexity is under the 'strange attraction' of non-esterified fatty acids. , 1997, Prostaglandins, leukotrienes, and essential fatty acids.

[15]  J. McGarry,et al.  Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat. , 1996, The Journal of clinical investigation.

[16]  J. Clement,et al.  Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion. , 1995, Science.

[17]  C. Newgard,et al.  Metabolic coupling factors in pancreatic beta-cell signal transduction. , 1995, Annual review of biochemistry.

[18]  B. Göke,et al.  Molecular cloning of a cDNA encoding for the GLP-1 receptor expressed in rat lung. , 2009, Experimental and clinical endocrinology.

[19]  M. Berelowitz,et al.  Tissue distribution of somatostatin receptor subtype messenger ribonucleic acid in the rat. , 1993, Endocrinology.

[20]  R. Jensen,et al.  Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Miyazaki,et al.  Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms. , 1990, Endocrinology.

[22]  P. Seeburg,et al.  A novel subtype of muscarinic receptor identified by homology screening. , 1987, Biochemical and biophysical research communications.

[23]  C. Wollheim,et al.  Signal Transduction in Insulin Secretion: , 1986 .

[24]  C. Wollheim,et al.  Signal transduction in insulin secretion: comparison between fuel stimuli and receptor agonists. , 1986, Annals of the New York Academy of Sciences.

[25]  A. A. Spector,et al.  Letter: Fatty acids, platelets, and microcirculatory obstruction , 1975, Science.

[26]  A. A. Spector,et al.  Fatty Acids, Platelets, and Microcirculatory Obstruction , 1975 .

[27]  P. Lacy,et al.  Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas , 1967, Diabetes.