Pharmacokinetics, bioavailability, excretion, and metabolic analysis of Schisanlactone E, a bioactive ingredient from Kadsura heteroclita (Roxb) Craib, in rats by UHPLC-MS/MS and UHPLC-Q-Orbitrap HRMS.

[1]  Qiong-Wei Yu,et al.  Profiling of benzimidazoles and related metabolites in pig serum based on SiO2@NiO solid-phase extraction combined precursor ion scan with high resolution orbitrap mass spectrometry. , 2019, Food chemistry.

[2]  Huang Yu,et al.  Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb. , 2019, Journal of ethnopharmacology.

[3]  Yuting Chen,et al.  UHPLC‐Q‐TOF‐MS/MS method based on four‐step strategy for metabolites of hinokiflavone in vivo and in vitro , 2019, Journal of pharmaceutical and biomedical analysis.

[4]  Xianqin Wang,et al.  Determination and pharmacokinetic study of echinatin by UPLC‐MS/MS in rat plasma , 2019, Journal of pharmaceutical and biomedical analysis.

[5]  Qiuhong Wang,et al.  Systematic screening and characterization of prototype constituents and metabolites of triterpenoid saponins of Caulopphyllum robustum Maxim using UPLC‐LTQ Orbitrap MS after oral administration in rats , 2019, Journal of pharmaceutical and biomedical analysis.

[6]  Yahong Zhu,et al.  In vitro and in vivo pharmacokinetics and metabolism of MK‐8353 by liquid chromatography combined with diode array detector and Q‐Exactive‐Orbitrap tandem mass spectrometry , 2019, Journal of pharmaceutical and biomedical analysis.

[7]  B. Li,et al.  Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats. , 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

[8]  Rongxia Liu,et al.  Identification and Quantification of Bioactive Compounds in Diaphragma juglandis Fructus by UHPLC-Q-Orbitrap HRMS and UHPLC-MS/MS. , 2019, Journal of agricultural and food chemistry.

[9]  Weidong Zhang,et al.  Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC‐QTOF/MS combined with multivariate statistical analysis , 2019, Journal of pharmaceutical and biomedical analysis.

[10]  Zhengtao Wang,et al.  Metabolic profiles and pharmacokinetics of picroside I in rats by liquid chromatography combined with electrospray ionization tandem mass spectrometry. , 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[11]  Yulin Feng,et al.  A targeted strategy to identify untargeted metabolites from in vitro to in vivo: Rapid and sensitive metabolites profiling of licorice in rats using ultra-high performance liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry. , 2018, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[12]  Sha Liu,et al.  Development, validation and comparison of surrogate matrix and surrogate analyte approaches with UHPLC-MS/MS to simultaneously quantify dopamine, serotonin and γ-aminobutyric acid in four rat brain regions. , 2018, Biomedical chromatography : BMC.

[13]  Yujie Zhang,et al.  Pharmacokinetics, metabolism, and excretion of cycloastragenol, a potent telomerase activator in rats , 2017, Xenobiotica; the fate of foreign compounds in biological systems.

[14]  R. Sane,et al.  Introduction of Drug Metabolism and Overview of Disease Effect on Drug Metabolism , 2017 .

[15]  Xiaochi Ma,et al.  Bioactive metabolites of Schisanlactone E transformed by Cunninghamella blakesleana AS 3.970. , 2014, Fitoterapia.

[16]  M. Meyer,et al.  Current applications of high-resolution mass spectrometry in drug metabolism studies , 2012, Analytical and Bioanalytical Chemistry.

[17]  Bhagwat Prasad,et al.  Metabolite identification by liquid chromatography-mass spectrometry , 2011 .

[18]  Michaela Scigelova,et al.  Coupling liquid chromatography to Orbitrap mass spectrometry. , 2010, Journal of chromatography. A.

[19]  D. Guo,et al.  Simultaneous Determination of Six Major Constituents in the Stems of Kadsura heteroclita by LC-DAD , 2006 .

[20]  Jian Han,et al.  New triterpenoids from Kadsura heteroclita and their cytotoxic activity. , 2006, Planta medica.