Acknowledgements

The author would like to express his indebtedness to Dr J. R. Cameron for suggesting and guiding this project. Advice and assistance received from Gordon Kenney, Dr H. Vermund, Dr B. Peckham, and Dr A. Schultz concerning some of the practical aspects of the problems are gratefully acknowledged. Manifold thanks are also due to the staff of the Numerical Analysis Laboratory. They have been most helpful. Financial support for this work has been received from the National Institutes of Health (CRT-5104 and CA-06295-03). Computer time spent developing and testing the programs was supported by the Research Committee of the Graduate School from funds supplied by the Wisconsin Alumni Research Foundation.