An analysis of aging-related genes derived from the Genotype-Tissue Expression project (GTEx)

[1]  Steven J. M. Jones,et al.  Oncogenic Signaling Pathways in The Cancer Genome Atlas. , 2018, Cell.

[2]  Steven J. M. Jones,et al.  Comprehensive Characterization of Cancer Driver Genes and Mutations , 2018, Cell.

[3]  P. Pizzo,et al.  The Aging Mitochondria , 2018, Genes.

[4]  Evan Bolton,et al.  Database resources of the National Center for Biotechnology Information , 2017, Nucleic Acids Res..

[5]  David S. Wishart,et al.  DrugBank 5.0: a major update to the DrugBank database for 2018 , 2017, Nucleic Acids Res..

[6]  Mark E. Robson,et al.  Identification and Functional Characterization of EGFR V769M, a Novel Germline Variant Associated With Multiple Lung Adenocarcinomas. , 2017, JCO precision oncology.

[7]  Moriah H Nissan,et al.  OncoKB: A Precision Oncology Knowledge Base. , 2017, JCO precision oncology.

[8]  Christie S. Chang,et al.  The BioGRID interaction database: 2017 update , 2016, Nucleic Acids Res..

[9]  S. Berger,et al.  Epigenetic Mechanisms of Longevity and Aging , 2016, Cell.

[10]  A. Shaw,et al.  Host Resistance and Immune Aging. , 2016, Clinics in geriatric medicine.

[11]  A. Brunet,et al.  The Aging Epigenome. , 2016, Molecular cell.

[12]  E. Epel,et al.  Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection , 2015, Science.

[13]  Ricardo Villamarín-Salomón,et al.  ClinVar: public archive of interpretations of clinically relevant variants , 2015, Nucleic Acids Res..

[14]  Andres Metspalu,et al.  The transcriptional landscape of age in human peripheral blood , 2015, Nature Communications.

[15]  Bairong Shen,et al.  New genes drive the evolution of gene interaction networks in the human and mouse genomes , 2015, Genome Biology.

[16]  Andrew B. Nobel,et al.  Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases , 2015, Scientific Reports.

[17]  G. Kempermann.  Faculty Opinions recommendation of Human genomics. The Genotype-Tissue Expression (GTEx) pilot analysis: multitissue gene regulation in humans. , 2015 .

[18]  Dmitri D. Pervouchine,et al.  The human transcriptome across tissues and individuals , 2015, Science.

[19]  Jun S. Liu,et al.  The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans , 2015, Science.

[20]  Núria Queralt-Rosinach,et al.  DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes , 2015, Database J. Biol. Databases Curation.

[21]  E. Dermitzakis,et al.  Gene age predicts the strength of purifying selection acting on gene expression variation in humans. , 2014, American journal of human genetics.

[22]  Lewis Y. Geer,et al.  Database resources of the National Center for Biotechnology Information , 2014, Nucleic Acids Res..

[23]  O. Phillipson.  Management of the aging risk factor for Parkinson's disease , 2014, Neurobiology of Aging.

[24]  Ruth R. Montgomery,et al.  Age-dependent dysregulation of innate immunity , 2013, Nature Reviews Immunology.

[25]  P. Stenson,et al.  The Human Gene Mutation Database: building a comprehensive mutation repository for clinical and molecular genetics, diagnostic testing and personalized genomic medicine , 2013, Human Genetics.

[26]  Andrew E. Teschendorff,et al.  Age-associated epigenetic drift: implications, and a case of epigenetic thrift? , 2013, Human molecular genetics.

[27]  Leopold Parts,et al.  Gene expression changes with age in skin, adipose tissue, blood and brain , 2013, Genome Biology.

[28]  L. Partridge,et al.  The Hallmarks of Aging , 2013, Cell.

[29]  L. Partridge,et al.  Genetics of longevity in model organisms: debates and paradigm shifts. , 2013, Annual review of physiology.

[30]  N. Sharpless,et al.  Review: a meta‐analysis of GWAS and age‐associated diseases , 2012, Aging cell.

[31]  Linda Partridge,et al.  Ageing as a Risk Factor for Disease , 2012, Current Biology.

[32]  David A Sinclair,et al.  The intersection between aging and cardiovascular disease. , 2012, Circulation research.

[33]  R. Weindruch,et al.  The caloric restriction paradigm: Implications for healthy human aging , 2012, American journal of human biology : the official journal of the Human Biology Council.

[34]  Peer Bork,et al.  OGEE: an online gene essentiality database , 2011, Nucleic Acids Res..

[35]  S. Bandinelli,et al.  Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing , 2011, Aging cell.

[36]  Syed Haider,et al.  Ensembl BioMarts: a hub for data retrieval across taxonomic space , 2011, Database J. Biol. Databases Curation.

[37]  Ian M. Fingerman,et al.  Database resources of the National Center for Biotechnology Information , 2010, Nucleic Acids Res..

[38]  M. Lachmann,et al.  MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain. , 2010, Genome research.

[39]  C. Kenyon.  The genetics of ageing , 2010, Nature.

[40]  J. Hoeijmakers.  DNA damage, aging, and cancer. , 2009, The New England journal of medicine.

[41]  Steven J. M. Jones,et al.  Circos: an information aesthetic for comparative genomics. , 2009, Genome research.

[42]  G. Church,et al.  Meta-analysis of age-related gene expression profiles identifies common signatures of aging , 2009, Bioinform..

[43]  C. Cotman,et al.  Gene expression changes in the course of normal brain aging are sexually dimorphic , 2008, Proceedings of the National Academy of Sciences.

[44]  Jan Vijg,et al.  Puzzles, promises and a cure for ageing , 2008, Nature.

[45]  Aric Hagberg,et al.  Exploring Network Structure, Dynamics, and Function using NetworkX , 2008, Proceedings of the Python in Science Conference.

[46]  Simo V. Zhang,et al.  A map of human cancer signaling , 2007, Molecular systems biology.

[47]  Manuel Serrano,et al.  The common biology of cancer and ageing , 2007, Nature.

[48]  L. Christiansen,et al.  Genetic dissection of gene expression observed in whole blood samples of elderly Danish twins , 2005, Human Genetics.

[49]  T. Prolla,et al.  Gene expression profiling studies of aging in cardiac and skeletal muscles. , 2005, Cardiovascular research.

[50]  S. Batalov,et al.  A gene atlas of the mouse and human protein-encoding transcriptomes. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[51]  Stephen Welle,et al.  Skeletal muscle gene expression profiles in 20–29 year old and 65–71 year old women , 2004, Experimental Gerontology.

[52]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[53]  R. Hébert,et al.  Risk factors for Alzheimer's disease: a prospective analysis from the Canadian Study of Health and Aging. , 2002, American journal of epidemiology.

[54]  G. Church,et al.  A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression , 2000, Nature Genetics.

[55]  JaakkoTuomilehto,et al.  Sex, Age, Cardiovascular Risk Factors, and Coronary Heart Disease , 1999 .

[56]  E. Vartiainen,et al.  Sex, age, cardiovascular risk factors, and coronary heart disease: a prospective follow-up study of 14 786 middle-aged men and women in Finland. , 1999, Circulation.

[57]  D. Lipman,et al.  Inaugural Article: The universal distribution of evolutionary rates of genes and distinct characteristics of eukaryotic genes of different apparent ages , 2009 .

[58]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[59]  Hong-Yu Ou,et al.  EG: a database of essential genes , 2004, Nucleic Acids Res..