The surface area of human V1 predicts the subjective experience of object size

The surface area of human primary visual cortex (V1) varies substantially between individuals for unknown reasons. We found that this variability was strongly and negatively correlated with the magnitude of two common visual illusions, where two physically identical objects appear different in size as a result of their context. Because such illusions dissociate conscious perception from physical stimulation, our findings indicate that the surface area of V1 predicts variability in conscious experience.

[1]  Lawrence C. Sincich,et al.  Complete Pattern of Ocular Dominance Columns in Human Primary Visual Cortex , 2007, The Journal of Neuroscience.

[2]  Roger B. H. Tootell,et al.  Does Retinotopy Influence Cortical Folding in Primate Visual Cortex? , 2009, The Journal of Neuroscience.

[3]  M. Sereno,et al.  Retinotopy and Attention in Human Occipital, Temporal, Parietal, and Frontal Cortex , 2008 .

[4]  U. Frith,et al.  Vagaries of Visual Perception in Autism , 2005, Neuron.

[5]  T. Wiesel,et al.  Columnar specificity of intrinsic horizontal and corticocortical connections in cat visual cortex , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[6]  Krish D. Singh,et al.  Orientation Discrimination Performance Is Predicted by GABA Concentration and Gamma Oscillation Frequency in Human Primary Visual Cortex , 2009, The Journal of Neuroscience.

[7]  GERALD H. FISHER Detection of Visual Stimuli located within Angles , 1967, Nature.

[8]  A. Dale,et al.  Cortical Surface-Based Analysis II: Inflation, Flattening, and a Surface-Based Coordinate System , 1999, NeuroImage.

[9]  D H Brainard,et al.  The Psychophysics Toolbox. , 1997, Spatial vision.

[10]  J. Zeman,et al.  quantitative evaluation of by , 2010 .

[11]  C. Frith,et al.  The neural correlates of conscious experience: an experimental framework , 1999, Trends in Cognitive Sciences.

[12]  D. Kersten,et al.  Attention-Dependent Representation of a Size Illusion in Human V1 , 2008, Current Biology.

[13]  J W Belliveau,et al.  Borders of multiple visual areas in humans revealed by functional magnetic resonance imaging. , 1995, Science.

[14]  D W Massaro,et al.  Judgmental model of the Ebbinghaus illusion. , 1971, Journal of experimental psychology.

[15]  D. Fitzpatrick,et al.  Orientation Selectivity and the Arrangement of Horizontal Connections in Tree Shrew Striate Cortex , 1997, The Journal of Neuroscience.

[16]  R. Rosenfeld Nature , 2009, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[17]  J. Davidoff,et al.  More accurate size contrast judgments in the Ebbinghaus Illusion by a remote culture. , 2007, Journal of experimental psychology. Human perception and performance.

[18]  D. Wilkin,et al.  Neuron , 2001, Brain Research.

[19]  Michael A. Silver,et al.  Spatial attention improves reliability of fMRI retinotopic mapping signals in occipital and parietal cortex , 2010, NeuroImage.

[20]  Robert O. Duncan,et al.  Cortical Magnification within Human Primary Visual Cortex Correlates with Acuity Thresholds , 2003, Neuron.

[21]  D. Kersten,et al.  The representation of perceived angular size in human primary visual cortex , 2006, Nature Neuroscience.

[22]  Robert Turner,et al.  Image Distortion Correction in fMRI: A Quantitative Evaluation , 2002, NeuroImage.

[23]  B. Fischer,et al.  Visual field representations and locations of visual areas V1/2/3 in human visual cortex. , 2003, Journal of vision.

[24]  M. D’Esposito,et al.  Cholinergic Enhancement Reduces Spatial Spread of Visual Responses in Human Early Visual Cortex , 2008, Neuron.