Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life

[1]  Fulvio Reggiori,et al.  Retraction notice to: role of the SEL1L:LC3-I complex as an ERAD tuning receptor in the mammalian ER. , 2014, Molecular cell.

[2]  Rebecca C Taylor,et al.  XBP-1 Is a Cell-Nonautonomous Regulator of Stress Resistance and Longevity , 2013, Cell.

[3]  Yingyu Chen,et al.  Transmembrane Protein 208: A Novel ER-Localized Protein That Regulates Autophagy and ER Stress , 2013, PloS one.

[4]  R. Kaufman,et al.  Targeting endoplasmic reticulum stress in metabolic disease , 2013, Expert opinion on therapeutic targets.

[5]  Yasushi Hiraoka,et al.  Autophagosomes form at ER–mitochondria contact sites , 2013, Nature.

[6]  D. Lomas,et al.  A Novel Interaction Between Aging and ER Overload in a Protein Conformational Dementia , 2013, Genetics.

[7]  T. Nyström,et al.  Effects of aging and reproduction on protein quality control in soma and gametes of Drosophila melanogaster , 2012, Aging cell.

[8]  G. Ruvkun,et al.  Induction of Cytoprotective Pathways Is Central to the Extension of Lifespan Conferred by Multiple Longevity Pathways , 2012, PLoS genetics.

[9]  Riccardo Bernasconi,et al.  RETRACTED: Role of the SEL1L:LC3-I Complex as an ERAD Tuning Receptor in the Mammalian ER , 2012, Molecular Cell.

[10]  N. Naidoo,et al.  The endoplasmic reticulum stress response in aging and age-related diseases , 2012, Front. Physio..

[11]  I. Tabas,et al.  Role of endoplasmic reticulum stress in metabolic disease and other disorders. , 2012, Annual review of medicine.

[12]  P. Walter,et al.  The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation , 2011, Science.

[13]  A. Meléndez,et al.  Autophagy and Lipid Metabolism Coordinately Modulate Life Span in Germline-less C. elegans , 2011, Current Biology.

[14]  F. Slack,et al.  Longevity and stress in Caenorhabditis elegans , 2011, Aging.

[15]  D. Rubinsztein,et al.  Protein misfolding disorders and macroautophagy , 2011, Current opinion in cell biology.

[16]  A. Cuervo,et al.  Protein homeostasis and aging: The importance of exquisite quality control , 2011, Ageing Research Reviews.

[17]  H. Coller,et al.  The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism. , 2010, Genes & development.

[18]  J. Cho,et al.  Protein N-glycosylation, protein folding, and protein quality control , 2010, Molecules and cells.

[19]  L. Wells,et al.  Intracellular protein glycosylation modulates insulin mediated lifespan in C. elegans , 2010, Aging.

[20]  Peter M. Douglas,et al.  Protein homeostasis and aging in neurodegeneration , 2010, The Journal of cell biology.

[21]  Masashi Tanaka,et al.  Trehalose extends longevity in the nematode Caenorhabditis elegans , 2010, Aging cell.

[22]  Li Yu,et al.  C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms , 2010, Cell.

[23]  Mark A. McCormick,et al.  Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity , 2010, Proceedings of the National Academy of Sciences.

[24]  C. Kenyon.  The genetics of ageing , 2010, Nature.

[25]  Z. Wang,et al.  ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy , 2010, Autophagy.

[26]  A. Kakizuka,et al.  Glucosamine induces autophagy via an mTOR-independent pathway. , 2010, Biochemical and biophysical research communications.

[27]  Frank Sinner,et al.  Induction of autophagy by spermidine promotes longevity , 2009, Nature Cell Biology.

[28]  Henry R. Bigelow,et al.  MAQGene: software to facilitate C. elegans mutant genome sequence analysis , 2009, Nature Methods.

[29]  D. Lomas,et al.  Endoplasmic Reticulum-associated Degradation (ERAD) and Autophagy Cooperate to Degrade Polymerogenic Mutant Serpins* , 2009, The Journal of Biological Chemistry.

[30]  Richard I. Morimoto,et al.  Adapting Proteostasis for Disease Intervention , 2008, Science.

[31]  D. Klionsky,et al.  Endoplasmic Reticulum Stress: A New Pathway to Induce Autophagy , 2007, Autophagy.

[32]  Kenjiro Sakaki,et al.  Genetic Interactions Due to Constitutive and Inducible Gene Regulation Mediated by the Unfolded Protein Response in C. elegans , 2005, PLoS genetics.

[33]  T. Sommer,et al.  ERAD: the long road to destruction , 2005, Nature Cell Biology.

[34]  David E Hill,et al.  Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. , 2004, Genome research.

[35]  R. Morimoto,et al.  Regulation of longevity in Caenorhabditis elegans by heat shock factor and molecular chaperones. , 2003, Molecular biology of the cell.

[36]  D. Hall,et al.  Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in C. elegans , 2003, Science.

[37]  R. Kamath,et al.  Genome-wide RNAi screening in Caenorhabditis elegans. , 2003, Methods.

[38]  Cynthia Kenyon,et al.  Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor , 2003, Science.

[39]  David H. Hall,et al.  Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34 , 2001, Neurobiology of Aging.

[40]  A. J. Parodi,et al.  Role of N-oligosaccharide endoplasmic reticulum processing reactions in glycoprotein folding and degradation. , 2000, The Biochemical journal.

[41]  W. Johnson.  Late‐onset neurodegenerative diseases—the role of protein insolubility , 2000, Journal of anatomy.

[42]  R. Plemper,et al.  Genetic interactions of Hrd3p and Der3p/Hrd1p with Sec61p suggest a retro-translocation complex mediating protein transport for ER degradation. , 1999, Journal of cell science.

[43]  J. Rine,et al.  Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. , 1996, Molecular biology of the cell.

[44]  C. Link,et al.  Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[45]  N. Munakata.  [Genetics of Caenorhabditis elegans]. , 1989, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

[46]  Kailiang Jia,et al.  Autophagy and longevity: lessons from C. elegans. , 2010, Advances in experimental medicine and biology.

[47]  Patrick W. Hullett,et al.  BMC Genomics BioMed Central Methodology article Rapid single nucleotide polymorphism mapping in C. elegans , 2005 .

[48]  J. Wixon,et al.  Caenorhabditis Elegans , 2000, Yeast.

[49]  A. Nakano,et al.  Identification of SEC12, SED4, truncated SEC16, and EKS1/HRD3 as multicopy suppressors of ts mutants of Sar1 GTPase. , 1999, Journal of biochemistry.

[50]  R. Plemper,et al.  Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins. , 1998, Molecular biology of the cell.