Labor inhibits placental mechanistic target of rapamycin complex 1 signaling.

[1]  Thomas Jansson,et al.  Increasing Maternal Body Mass Index Is Associated with Systemic Inflammation in the Mother and the Activation of Distinct Placental Inflammatory Pathways1 , 2014, Biology of reproduction.

[2]  D. Charnock-Jones,et al.  Influence of speed of sample processing on placental energetics and signalling pathways: Implications for tissue collection☆ , 2014, Placenta.

[3]  Y. Kanai,et al.  Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells , 2013, The Journal of physiology.

[4]  E. Chien,et al.  Effects of labor on placental fatty acid β oxidation , 2013, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[5]  K. Bence,et al.  Central Regulation of Metabolism by Protein Tyrosine Phosphatases , 2012, Front. Neurosci..

[6]  D. Sabatini,et al.  A unifying model for mTORC1-mediated regulation of mRNA translation , 2012, Nature.

[7]  D. Sabatini,et al.  mTOR Signaling in Growth Control and Disease , 2012, Cell.

[8]  Joseph Avruch,et al.  Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update. , 2012, Physiological reviews.

[9]  C. Vaillancourt,et al.  Stability of reference proteins in human placenta: general protein stains are the benchmark. , 2012, Placenta.

[10]  J. Ruland Return to homeostasis: downregulation of NF-κB responses , 2011, Nature Immunology.

[11]  D. Charnock-Jones,et al.  Regulation of AKT Phosphorylation at Ser473 and Thr308 by Endoplasmic Reticulum Stress Modulates Substrate Specificity in a Severity Dependent Manner , 2011, PloS one.

[12]  J. Kang,et al.  Global gene expression changes induced in the human placenta during labor. , 2010, Placenta.

[13]  D. Golenbock,et al.  Inflammasomes: too big to miss. , 2009, The Journal of clinical investigation.

[14]  T. Powell,et al.  Regulation of amino acid transporters by glucose and growth factors in cultured primary human trophoblast cells is mediated by mTOR signaling. , 2009, American journal of physiology. Cell physiology.

[15]  H. Lane,et al.  Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition , 2009, Molecular Cancer Therapeutics.

[16]  G. Rice,et al.  Transcriptional regulation of the processes of human labour and delivery. , 2009, Placenta.

[17]  G. Rice,et al.  Peroxisome proliferator-activated receptors and retinoid X receptor-alpha in term human gestational tissues: tissue specific and labour-associated changes. , 2009, Placenta.

[18]  Y. Kanai,et al.  Regulation of placental amino acid transporter activity by mammalian target of rapamycin. , 2009, American journal of physiology. Cell physiology.

[19]  B. Manning,et al.  The TSC1-TSC2 complex: a molecular switchboard controlling cell growth. , 2008, The Biochemical journal.

[20]  R. Romero,et al.  Evidence of the involvement of caspase-1 under physiologic and pathologic cellular stress during human pregnancy: A link between the inflammasome and parturition , 2008, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[21]  D. Charnock-Jones,et al.  Oxidative stress, gene expression, and protein changes induced in the human placenta during labor. , 2007, The American journal of pathology.

[22]  T. Powell,et al.  Mammalian target of rapamycin in the human placenta regulates leucine transport and is down‐regulated in restricted fetal growth , 2007, The Journal of physiology.

[23]  G. Matarese,et al.  The weight of leptin in immunity , 2004, Nature Reviews Immunology.

[24]  M. Mitchell,et al.  Cytokines, prostaglandins and parturition--a review. , 2003, Placenta.

[25]  Jane E Norman,et al.  Leukocyte density and pro-inflammatory cytokine expression in human fetal membranes, decidua, cervix and myometrium before and during labour at term. , 2003, Molecular human reproduction.

[26]  M. Turner,et al.  Secretion of Interleukin-1β and Interleukin-6 by Fragments of Term Human Placental Villi: Signalling Pathways and Effects of Tumour Necrosis Factor α and Mode of Delivery , 2002 .

[27]  M. Mitchell,et al.  Identification of suppressors of cytokine signaling (SOCS) proteins in human gestational tissues: differential regulation is associated with the onset of labor. , 2002, The Journal of clinical endocrinology and metabolism.

[28]  M. Turner,et al.  Secretion of interleukin-1beta and interleukin-6 by fragments of term human placental villi: signalling pathways and effects of tumour necrosis factor alpha and mode of delivery. , 2002, Placenta.

[29]  S K Burley,et al.  Hierarchical phosphorylation of the translation inhibitor 4E-BP1. , 2001, Genes & development.

[30]  M. Heim The Jak-STAT pathway: cytokine signalling from the receptor to the nucleus. , 1999, Journal of receptor and signal transduction research.

[31]  E. Rutanen,et al.  The interleukin-1 system in gestational tissues at term: effect of labour. , 1997, Placenta.