Determination of Uric Acid and Norepinephrine by Chitosan-Multiwall Carbon Nanotube Modified Electrode

A novel chemically modified electrode based on the chitosan-multiwall carbon nanotube (MWNT) coated glassy carbon electrode (GCE) is described, which exhibited an attractive ability to determine uric acid (UA) and norepinephrine (NE) simultaneously. The responses of UA and NE merged into a large peak at a bare GCE, but yielded two well-defined oxidation peaks at the chitosan-MWNT modified GCE (MC/GCE). The experimental parameters were optimized, and a direct electrochemical method for the simultaneous determine for UA and NE is proposed. The MC/GCE showed good sensitivity, selectivity and stability.

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