Higher-order genome organization in human disease.
暂无分享,去创建一个
[1] Jie Zhang,et al. Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer , 2009, Cell.
[2] T. Misteli,et al. Aging-related chromatin defects via loss of the NURD complex , 2009, Nature Cell Biology.
[3] John H. Wilson,et al. Instability and chromatin structure of expanded trinucleotide repeats. , 2009, Trends in genetics : TIG.
[4] V. Corces,et al. CTCF: Master Weaver of the Genome , 2009, Cell.
[5] P. Jeggo,et al. The impact of heterochromatin on DSB repair. , 2009, Biochemical Society transactions.
[6] C. K. Schmidt,et al. Conserved features of cohesin binding along fission yeast chromosomes , 2009, Genome Biology.
[7] J. Aten,et al. Heterochromatin protein 1 is recruited to various types of DNA damage , 2009, The Journal of cell biology.
[8] B. Emerson,et al. Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary. , 2009, Molecular cell.
[9] A. Shilatifard,et al. Histone H4 lysine-16 acetylation regulates cellular lifespan , 2009, Nature.
[10] T. Misteli,et al. Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma , 2009, Proceedings of the National Academy of Sciences.
[11] D. Dorsett. Cohesin, gene expression and development: Lessons from Drosophila , 2009, Chromosome Research.
[12] T. Misteli,et al. The emerging role of nuclear architecture in DNA repair and genome maintenance , 2009, Nature Reviews Molecular Cell Biology.
[13] Nathaniel D. Heintzman,et al. Histone modifications at human enhancers reflect global cell-type-specific gene expression , 2009, Nature.
[14] I. Krantz,et al. On the Molecular Etiology of Cornelia de Lange Syndrome , 2009, Annals of the New York Academy of Sciences.
[15] L. Wallrath,et al. Linking Heterochromatin Protein 1 (HP1) to cancer progression. , 2008, Mutation research.
[16] J. Gerton,et al. Cohesinopathies: One ring, many obligations. , 2008, Mutation research.
[17] F. Alt,et al. SIRT1 Redistribution on Chromatin Promotes Genomic Stability but Alters Gene Expression during Aging , 2008, Cell.
[18] J. Peters,et al. The cohesin complex and its roles in chromosome biology. , 2008, Genes & development.
[19] Stephen J. Tapscott,et al. CTCF cis-Regulates Trinucleotide Repeat Instability in an Epigenetic Manner: A Novel Basis for Mutational Hot Spot Determination , 2008, PLoS genetics.
[20] G. Gerlitz,et al. The Activation Of ATM Depends On Chromatin Interactions Occurring Prior To DNA-Damage Induction , 2008, Nature Cell Biology.
[21] R. Eisenman,et al. Myc's broad reach. , 2008, Genes & development.
[22] T. Itoh,et al. Identification of cis-acting sites for condensin loading onto budding yeast chromosomes. , 2008, Genes & development.
[23] A. Hoffman,et al. CTCF Regulates Allelic Expression of Igf2 by Orchestrating a Promoter-Polycomb Repressive Complex 2 Intrachromosomal Loop , 2008, Molecular and Cellular Biology.
[24] P. Jeggo,et al. ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. , 2008, Molecular cell.
[25] A. Jeyasekharan,et al. HP1-β mobilization promotes chromatin changes that initiate the DNA damage response , 2008, Nature.
[26] L. Fanti,et al. HP1: a functionally multifaceted protein. , 2008, Current opinion in genetics & development.
[27] T. Eggermann,et al. Growth retardation versus overgrowth: Silver-Russell syndrome is genetically opposite to Beckwith-Wiedemann syndrome. , 2008, Trends in genetics : TIG.
[28] B. Chadwick,et al. The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions , 2008, The Journal of experimental medicine.
[29] J. Russo,et al. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis , 2008, Nature.
[30] P. Casaccia‐Bonnefil,et al. Epigenetic memory loss in aging oligodendrocytes in the corpus callosum , 2008, Neurobiology of Aging.
[31] H. Aburatani,et al. Cohesin mediates transcriptional insulation by CCCTC-binding factor , 2008, Nature.
[32] Stephan Sauer,et al. Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms , 2008, Cell.
[33] Michael B. Eisen,et al. Association of cohesin and Nipped-B with transcriptionally active regions of the Drosophila melanogaster genome , 2008, Chromosoma.
[34] Seung-Min Yang,et al. Global chromatin compaction limits the strength of the DNA damage response , 2007, The Journal of cell biology.
[35] D. Sinclair,et al. The role of nuclear architecture in genomic instability and ageing , 2007, Nature Reviews Molecular Cell Biology.
[36] Manel Esteller,et al. Epigenetics and aging: the targets and the marks. , 2007, Trends in genetics : TIG.
[37] Cameron S. Osborne,et al. Myc Dynamically and Preferentially Relocates to a Transcription Factory Occupied by Igh , 2007, PLoS biology.
[38] H. Zoghbi,et al. Trinucleotide repeat disorders. , 2007, Annual review of neuroscience.
[39] M. Nussenzweig,et al. Chromatin dynamics and the preservation of genetic information , 2007, Nature.
[40] P. Knoepfler. Myc goes global: new tricks for an old oncogene. , 2007, Cancer research.
[41] Gaudenz Danuser,et al. Positional stability of single double-strand breaks in mammalian cells , 2007, Nature Cell Biology.
[42] P. Fraser,et al. Nuclear organization of the genome and the potential for gene regulation , 2007, Nature.
[43] B. Johansson,et al. The impact of translocations and gene fusions on cancer causation , 2007, Nature Reviews Cancer.
[44] J. Chung,et al. Analysis of the H19ICR Insulator , 2007, Molecular and Cellular Biology.
[45] T. Misteli. Beyond the Sequence: Cellular Organization of Genome Function , 2007, Cell.
[46] M. Bustin,et al. HMG chromosomal proteins in development and disease. , 2007, Trends in cell biology.
[47] Tom Misteli,et al. Spatial genome organization in the formation of chromosomal translocations. , 2007, Seminars in cancer biology.
[48] T. Cremer,et al. Dynamic genome architecture in the nuclear space: regulation of gene expression in three dimensions , 2007, Nature Reviews Genetics.
[49] Tom Misteli,et al. Cell biology: Chromosome territories , 2007, Nature.
[50] A. Belmont. Mitotic chromosome structure and condensation. , 2006, Current opinion in cell biology.
[51] K. Sandhu,et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions , 2006, Nature Genetics.
[52] Wouter de Laat,et al. CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus. , 2006, Genes & development.
[53] Rolf Ohlsson,et al. CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[54] M. Hendrix,et al. A Requirement for Dimerization of HP1Hsα in Suppression of Breast Cancer Invasion* , 2006, Journal of Biological Chemistry.
[55] Philip R. Gafken,et al. Myc influences global chromatin structure , 2006, The EMBO journal.
[56] F. Collins,et al. Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[57] Thomas Cremer,et al. Chromosome territories--a functional nuclear landscape. , 2006, Current opinion in cell biology.
[58] T. Kohwi-Shigematsu,et al. SATB1 packages densely looped, transcriptionally active chromatin for coordinated expression of cytokine genes , 2006, Nature Genetics.
[59] T. Misteli,et al. Lamin A-Dependent Nuclear Defects in Human Aging , 2006, Science.
[60] R. Benya,et al. Consequence of gastrin-releasing peptide receptor activation in a human colon cancer cell line: a proteomic approach. , 2006, Journal of proteome research.
[61] A. Pombo,et al. Intermingling of Chromosome Territories in Interphase Suggests Role in Translocations and Transcription-Dependent Associations , 2006, PLoS biology.
[62] Hui Ling Chen,et al. CTCF Mediates Interchromosomal Colocalization Between Igf2/H19 and Wsb1/Nf1 , 2006, Science.
[63] James G. McNally,et al. Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks , 2006, The Journal of cell biology.
[64] A. Stein,et al. Histone H1 Depletion in Mammals Alters Global Chromatin Structure but Causes Specific Changes in Gene Regulation , 2005, Cell.
[65] Yosef Gruenbaum,et al. Age-related changes of nuclear architecture in Caenorhabditis elegans. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[66] M. Bustin,et al. Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3 , 2005, The EMBO journal.
[67] E. Jabs,et al. Roberts syndrome is caused by mutations in ESCO2, a human homolog of yeast ECO1 that is essential for the establishment of sister chromatid cohesion , 2005, Nature Genetics.
[68] K. Lindblad-Toh,et al. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals , 2005, Nature.
[69] Tomoharu Kiyuna,et al. Alteration of chromosome positioning during adipocyte differentiation , 2004, Journal of Cell Science.
[70] Tom Misteli,et al. Spatial Positioning A New Dimension in Genome Function , 2004, Cell.
[71] Maria Vernucci,et al. Microdeletions in the human H19 DMR result in loss of IGF2 imprinting and Beckwith-Wiedemann syndrome , 2004, Nature Genetics.
[72] T. Itoh,et al. Cohesin relocation from sites of chromosomal loading to places of convergent transcription , 2004, Nature.
[73] Tom Misteli,et al. Tissue-specific spatial organization of genomes , 2004, Genome Biology.
[74] Yosef Gruenbaum,et al. Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson–Gilford progeria syndrome , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[75] I. Krantz,et al. Cornelia de Lange syndrome is caused by mutations in NIPBL, the human homolog of Drosophila melanogaster Nipped-B , 2004, Nature Genetics.
[76] Tom Strachan,et al. NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome , 2004, Nature Genetics.
[77] Tom Misteli,et al. Spatial proximity of translocation-prone gene loci in human lymphomas , 2003, Nature Genetics.
[78] T. Kohwi-Shigematsu,et al. Tissue-specific nuclear architecture and gene expession regulated by SATB1 , 2003, Nature Genetics.
[79] Michael Bustin,et al. Chromosomal protein HMGN1 enhances the rate of DNA repair in chromatin , 2003, The EMBO journal.
[80] M. Groudine,et al. Controlling the double helix , 2003, Nature.
[81] B. Sarg,et al. Postsynthetic Trimethylation of Histone H4 at Lysine 20 in Mammalian Tissues Is Associated with Aging* , 2002, The Journal of Biological Chemistry.
[82] R. Eisenman,et al. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. , 2002, Genes & development.
[83] Tom Misteli,et al. Conservation of Relative Chromosome Positioning in Normal and Cancer Cells , 2002, Current Biology.
[84] T. Poggio,et al. Prediction of central nervous system embryonal tumour outcome based on gene expression , 2002, Nature.
[85] M. Nikiforova,et al. Proximity of chromosomal loci that participate in radiation-induced rearrangements in human cells. , 2000, Science.
[86] J. Aten,et al. High resolution analysis of interphase chromosome domains. , 2000, Journal of cell science.
[87] M. Hendrix,et al. Down-regulation of HP1Hsalpha expression is associated with the metastatic phenotype in breast cancer. , 2000, Cancer research.
[88] M Kozubek,et al. The influence of the cell cycle, differentiation and irradiation on the nuclear location of the abl, bcr and c-myc genes in human leukemic cells. , 2000, Leukemia research.
[89] D. Dorsett,et al. Nipped-B, a Drosophila homologue of chromosomal adherins, participates in activation by remote enhancers in the cut and Ultrabithorax genes. , 1999, Genetics.
[90] J. Rine,et al. The boundaries of the silenced HMR domain in Saccharomyces cerevisiae. , 1999, Genes & development.
[91] A. Parreira,et al. The Nuclear Topography of ABL, BCR, PML, and RAR Genes: Evidence for Gene Proximity in Specific Phases of the Cell Cycle and Stages of Hematopoietic Differentiation , 1999 .
[92] M. Lagally,et al. In situ visualization of DNA double-strand break repair in human fibroblasts. , 1998, Science.
[93] L. Guarente,et al. Extrachromosomal rDNA Circles— A Cause of Aging in Yeast , 1997, Cell.
[94] Michal Kozubek,et al. Localisation and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukaemia , 1997, Human Genetics.
[95] Y. Kohwi,et al. A tissue-specific MAR SAR DNA-binding protein with unusual binding site recognition , 1992, Cell.
[96] R. Cutler,et al. Mouse satellite DNA is transcribed in senescent cardiac muscle. , 1990, The Journal of biological chemistry.
[97] C. Denniston,et al. The nonrandom participation of human acrocentric chromosomes in Robertsonian translocations , 1989, Annals of human genetics.
[98] V. L. Wilson,et al. DNA methylation decreases in aging but not in immortal cells. , 1983, Science.
[99] N. Schoenherr,et al. Are H19 Variants Associated with Silver-Russell Syndrome? , 2008, Journal of pediatric endocrinology & metabolism : JPEM.
[100] W. Bickmore,et al. Influences of chromosome size, gene density and nuclear position on the frequency of constitutional translocations in the human population , 2004, Chromosome Research.
[101] C. Cremer. NUCLEAR ARCHITECTURE AND GENE REGULATION IN MAMMALIAN CELLS , 2001 .
[102] Earl F. Glynn,et al. Genome-Wide Mapping of the Cohesin Complex in the Yeast Saccharomyces cerevisiae , 2004, PLoS biology.