Expression of the bitter receptor T2R38 in pancreatic cancer: localization in lipid droplets and activation by a bacteria-derived quorum-sensing molecule
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Peter Schirmacher | P. Schirmacher | M. Gaida | G. Wabnitz | Matthias M. Gaida | Sabine Stegmaier | Ulrike Dapunt | G. Hänsch | Christine Mayer | Guido H. Wabnitz | G. Maria Hänsch | U. Dapunt | C. Mayer | S. Stegmaier | Ulrike Dapunt
[1] M. Pishvaian,et al. Current Standards and Novel Treatment Options for Metastatic Pancreatic Adenocarcinoma. , 2015, Oncology.
[2] H. Jäckle,et al. Lipid droplets: A dynamic organelle moves into focus , 2010, FEBS letters.
[3] E. Rozengurt. Taste receptors in the gastrointestinal tract. I. Bitter taste receptors and alpha-gustducin in the mammalian gut. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[4] S. Zimmermann,et al. Induction of Neutrophil Chemotaxis by the Quorum-Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone , 2006, Infection and Immunity.
[5] A. Dvorak,et al. Roles and origins of leukocyte lipid bodies: proteomic and ultrastructural studies , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[6] M. Behrens,et al. Immunohistochemical Detection of TAS2R38 Protein in Human Taste Cells , 2012, PloS one.
[7] Brian Goodman,et al. The microbiome and cancer , 2018, The Journal of pathology.
[8] F. Gossé,et al. Chemopreventive effects of lupulone, a hop {beta}-acid, on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis. , 2007, Carcinogenesis.
[9] Michael R Hamblin,et al. CA : A Cancer Journal for Clinicians , 2011 .
[10] V. Viswanathan. Sensing bacteria, without bitterness? , 2013, Gut microbes.
[11] M. Kloor,et al. Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin , 2011, PloS one.
[12] J. Palmer,et al. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. , 2012, The Journal of clinical investigation.
[13] G. Hänsch. Editorial: Molecular eavesdropping: phagocytic cells spy on bacterial communication , 2012, Journal of leukocyte biology.
[14] C. la Vecchia,et al. Coffee reduces risk for hepatocellular carcinoma: an updated meta-analysis. , 2013, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[15] Jayaram Chandrashekar,et al. A Novel Family of Mammalian Taste Receptors , 2000, Cell.
[16] R. Lee,et al. Role of the bitter taste receptor T2R38 in upper respiratory infection and chronic rhinosinusitis , 2015, Current opinion in allergy and clinical immunology.
[17] Nisha Singh,et al. Differential expression of bitter taste receptors in non-cancerous breast epithelial and breast cancer cells. , 2014, Biochemical and biophysical research communications.
[18] A. Warth,et al. Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis , 2010, Modern Pathology.
[19] Monica C. Chen,et al. Colocalization of the α-subunit of gustducin with PYY and GLP-1 in L cells of human colon , 2006 .
[20] Frank Bergmann,et al. Selective inhibition of the p38 alternative activation pathway in infiltrating T cells inhibits pancreatic cancer progression , 2015, Nature Medicine.
[21] A. Pivoriūnas,et al. The Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone stimulates phagocytic activity in human macrophages through the p38 MAPK pathway. , 2005, Microbes and infection.
[22] P. Schirmacher,et al. Adipophilin/perilipin‐2 as a lipid droplet‐specific marker for metabolically active cells and diseases associated with metabolic dysregulation , 2013, Histopathology.
[23] M. Gottesman,et al. A novel way to spread drug resistance in tumor cells: functional intercellular transfer of P-glycoprotein (ABCB1). , 2005, Trends in pharmacological sciences.
[24] K. Janda,et al. N-(3-Oxo-acyl)homoserine Lactones Signal Cell Activation through a Mechanism distinct from the Canonical Pathogen-associated Molecular Pattern Recognition Receptor Pathways* , 2006, Journal of Biological Chemistry.
[25] Monica C. Chen,et al. Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon. , 2006, American journal of physiology. Gastrointestinal and liver physiology.
[26] S. Liggett,et al. Extraoral bitter taste receptors as mediators of off‐target drug effects , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[27] S. H. Young,et al. Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[28] Nisha Singh,et al. Functional bitter taste receptors are expressed in brain cells. , 2011, Biochemical and biophysical research communications.
[29] F. Shanahan. The colonic microbiota in health and disease , 2013, Current opinion in gastroenterology.
[30] Robert V Farese,et al. Lipid Droplets Finally Get a Little R-E-S-P-E-C-T , 2009, Cell.
[31] F. Gao,et al. Epigallocatechin gallate inhibits human tongue carcinoma cells via HK2‑mediated glycolysis. , 2015, Oncology reports.
[32] M. Welte. Proteins under new management: lipid droplets deliver. , 2007, Trends in cell biology.
[33] M. Behrens,et al. Human bitter taste perception. , 2005, Chemical senses.
[34] T. Giese,et al. Tasting Pseudomonas aeruginosa Biofilms: Human Neutrophils Express the Bitter Receptor T2R38 as Sensor for the Quorum Sensing Molecule N-(3-Oxododecanoyl)-l-Homoserine Lactone , 2015, Front. Immunol..
[35] Wenkang Huang,et al. Identification of Novel Compounds for Human Bitter Taste Receptors , 2014, Chemical biology & drug design.
[36] In-Wha Kim,et al. The power of the pump: mechanisms of action of P-glycoprotein (ABCB1). , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
[37] K. Magnusson,et al. N‐Acylhomoserine lactones are potent neutrophil chemoattractants that act via calcium mobilization and actin remodeling , 2012, Journal of leukocyte biology.
[38] N. Dubrawsky. Cancer statistics , 1989, CA: a cancer journal for clinicians.
[39] T. Osborne,et al. Gut bitter taste receptor signalling induces ABCB1 through a mechanism involving CCK. , 2011, The Biochemical journal.
[40] Yehuda Ben-Shahar,et al. Motile Cilia of Human Airway Epithelia Are Chemosensory , 2009, Science.
[41] T. Finger,et al. Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals , 2010, Proceedings of the National Academy of Sciences.
[42] R. Lee,et al. Taste receptors in innate immunity , 2014, Cellular and Molecular Life Sciences.
[43] Robert G. Parton,et al. Opinion: Lipid droplets: a unified view of a dynamic organelle , 2006, Nature Reviews Molecular Cell Biology.
[44] G. Brenner-Weiss,et al. Bacterial quorum sensing molecule induces chemotaxis of human neutrophils via induction of p38 and leukocyte specific protein 1 (LSP1). , 2013, Immunobiology.
[45] Helmut Friess,et al. Pancreatic cancer microenvironment , 2007, International journal of cancer.
[46] S. Zimmermann,et al. The quorum-sensing molecule N-3-oxododecanoyl homoserine lactone (3OC12-HSL) enhances the host defence by activating human polymorphonuclear neutrophils (PMN) , 2007, Analytical and bioanalytical chemistry.