Childhood Glaucoma: An Overview

Several types of childhood glaucoma exist, and the terminology is based on the time of onset of disease and its potential cause. Though childhood glaucoma occurs less commonly than adults but can lead to permanent visual damage due to amblyopia, optic neuropathy or refractive error. A detailed evaluation should be done to establish diagnosis. Medical therapy has a limited role and surgery remains main modality for treatment. Childhood glaucoma is a treatable disease, if early diagnosis is established and therapeutic intervention done in time. In children with low vision efforts should be there to maintain residual vision and visual rehabilitation with low vision aids should be done.

[1]  A. Mandal,et al.  Update on congenital glaucoma , 2011, Indian journal of ophthalmology.

[2]  S. Hasnain,et al.  Correlations of genotype with phenotype in Indian patients with primary congenital glaucoma. , 2004, Investigative ophthalmology & visual science.

[3]  R. Parrish,et al.  A comparison of latanoprost, bimatoprost, and travoprost in patients with elevated intraocular pressure: a 12-week, randomized, masked-evaluator multicenter study. , 2003, American journal of ophthalmology.

[4]  M. Sarfarazi,et al.  The Third Genetic Locus (GLC3C) for Primary Congenital Glaucoma (PCG) Maps to Chromosome 14q24.3 , 2002 .

[5]  L. Enyedi,et al.  Safety and efficacy of brimonidine in children with glaucoma. , 2001, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus.

[6]  M. Sarfarazi,et al.  Molecular genetics of primary congenital glaucoma , 2000, Eye.

[7]  E. Buckley,et al.  The effectiveness of latanoprost for the treatment of pediatric glaucoma. , 1999, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus.

[8]  R. Brubaker,et al.  Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol. , 1998, Archives of ophthalmology.

[9]  J. Lupski,et al.  Mutations in CYP1B1, the gene for cytochrome P4501B1, are the predominant cause of primary congenital glaucoma in Saudi Arabia. , 1998, American journal of human genetics.

[10]  E. Buckley,et al.  Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma. , 1998, Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus.

[11]  R. Ritch,et al.  Bleb-related ocular infection in children after trabeculectomy with mitomycin C. , 1997, Ophthalmology.

[12]  M. A. Walter,et al.  Autosomal dominant Axenfeld-Rieger anomaly maps to 6p25. , 1997, American journal of human genetics.

[13]  D. Walton,et al.  Mitomycin C-augmented trabeculectomy in refractory congenital glaucoma. , 1997, Ophthalmology.

[14]  M. Sarfarazi,et al.  Identification of three different truncating mutations in cytochrome P4501B1 (CYP1B1) as the principal cause of primary congenital glaucoma (Buphthalmos) in families linked to the GLC3A locus on chromosome 2p21. , 1997, Human molecular genetics.

[15]  M. Sarfarazi,et al.  A second locus (GLC3B) for primary congenital glaucoma (Buphthalmos) maps to the 1p36 region. , 1996, Human molecular genetics.

[16]  C. Foster,et al.  Changing patterns in uveitis of childhood. , 1996, Ophthalmology.

[17]  M. Sarfarazi,et al.  Assignment of a locus (GLC3A) for primary congenital glaucoma (Buphthalmos) to 2p21 and evidence for genetic heterogeneity. , 1995, Genomics.

[18]  A. Beck,et al.  360° Trabeculotomy for Primary Congenital Glaucoma , 1995 .

[19]  M. Nicolela,et al.  Mitomycin as Adjunct Chemotherapy with Trabeculectomy in Congenital and Developmental Glaucomas , 1995, Journal of glaucoma.

[20]  A. Negi,et al.  Surgical results of trabeculotomy ab externo for developmental glaucoma. , 1994, Archives of ophthalmology.

[21]  M. Jaafar,et al.  Effect of oral chloral hydrate sedation on the intraocular pressure measurement. , 1993, Journal of pediatric ophthalmology and strabismus.

[22]  V. Sheffield,et al.  Genetic linkage of familial open angle glaucoma to chromosome 1q21–q31 , 1993, Nature Genetics.

[23]  A. Kwitek,et al.  Clinical features and linkage analysis of a family with autosomal dominant juvenile glaucoma. , 1993, Ophthalmology.

[24]  R. Maas,et al.  Genomic structure, evolutionary conservation and aniridia mutations in the human PAX6 gene , 1992, Nature Genetics.

[25]  M. Oliver,et al.  Subconjunctival injection of 5-fluorouracil following trabeculectomy for congenital and infantile glaucoma. , 1992, Ophthalmic surgery.

[26]  K. Teichmann,et al.  Trabeculectomy versus trabeculotomy in congenital glaucoma. , 1989, The British journal of ophthalmology.

[27]  H. D. Hoskins,et al.  Clinical experience with timolol in childhood glaucoma. , 1985, Archives of ophthalmology.

[28]  H. D. Hoskins,et al.  Anatomical classification of the developmental glaucomas. , 1984, Archives of ophthalmology.

[29]  V. P. deLuise,et al.  Primary infantile glaucoma (congenital glaucoma). , 1983, Survey of ophthalmology.

[30]  Pressman Sh,et al.  Pediatric aphakic glaucoma. , 1983 .

[31]  D. Berry,et al.  Goniotomy vs external trabeculotomy for developmental glaucoma. , 1983, American journal of ophthalmology.

[32]  S. D. McPherson,et al.  External trabeculotomy for developmental glaucoma. , 1980, Ophthalmology.

[33]  R. Shaffer,et al.  The glaucomatous disc in infants. A suggested hypothesis for disc cupping. , 1969, Transactions - American Academy of Ophthalmology and Otolaryngology. American Academy of Ophthalmology and Otolaryngology.

[34]  K. Richardson,et al.  Optic-nerve cupping in congenital glaucoma. , 1966, American journal of ophthalmology.

[35]  R. Shaffer Genetics and the congenital glaucomas. , 1965, American journal of ophthalmology.

[36]  O. Barkan Pathogenesis of congenital glaucoma: gonioscopic and anatomic observation of the angle of the anterior chamber in the normal eye and in congenital glaucoma. , 1955, American journal of ophthalmology.

[37]  B. Black,et al.  The Treatment of Congenital Glaucoma * , 1950, The British journal of ophthalmology.

[38]  R. Bowman,et al.  Ocular and systemic side effects of brimonidine 0.2% eye drops (Alphagan®) in children , 2004, Eye.

[39]  K. Joos,et al.  An ocular endoscope enables a goniotomy despite a cloudy cornea. , 2001, Archives of ophthalmology.

[40]  A. Alm,et al.  Aqueous humor flow in human eyes treated with dorzolamide and different doses of acetazolamide. , 1998, Archives of ophthalmology.

[41]  Lonie Gunasekarage,et al.  Power, and C. , 1996 .

[42]  Walton Ds Pediatric aphakic glaucoma: a study of 65 patients. , 1995 .

[43]  D. Walton,et al.  Pediatric aphakic glaucoma: a study of 65 patients. , 1995, Transactions of the American Ophthalmological Society.

[44]  A. Tiret [Congenital glaucoma]. , 1991, Soins. Gynecologie, obstetrique, puericulture, pediatrie.

[45]  A. Genčík Epidemiology and genetics of primary congenital glaucoma in Slovakia. Description of a form of primary congenital glaucoma in gypsies with autosomal-recessive inheritance and complete penetrance. , 1989, Developments in ophthalmology.

[46]  G. Beauchamp,et al.  Filtering surgery in children: barriers to success. , 1979, Ophthalmology.

[47]  Miller Sj Genetic aspects of glaucoma. , 1966, Transactions of the ophthalmological societies of the United Kingdom.

[48]  J. Worst The pathogenesis of congenital glaucoma , 1966 .

[49]  B. Beiguelman [GENETIC ASPECTS OF GLAUCOMA]. , 1964, Arquivos brasileiros de oftalmologia.