FePO4 based single chamber air-cathode microbial fuel cell for online monitoring levofloxacin.

A bio-electrochemical strategy was developed for constructing a simple and sensitive levofloxacin (LEV) sensor based on a single chamber microbial fuel cell (SC-MFC) using FePO4 nanoparticles (NPs) as the cathode catalyst instead of traditional Pt/C. In this assembled sensor device, FePO4 NPs dramatically promoted the electrooxidation of oxygen on the cathode, which helps to accelerate the voltage output from SC-MFC and can provide a powerful guarantee for LEV detection. Scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS) were used to fully characterize the FePO4 NPs. Under the optimized COD condition (3mM), the LEV with a concentration range of 0.1-1000µg/L could be detected successfully, and exhibited the excellent linear interval in the concentration range of 0.1-100µg/L. During this range of concentrations of LEV, a temporary effect on the anode of exoelectrogenic bacterial in less than 10min could occur, and then came back to the normal. It exhibited a long-term stability, maintaining the stable electricity production for 14 months of continuous running. Besides, the detection mechanism was investigated by quantum chemical calculation using density functional theory (DFT).

[1]  Jiangfeng Qian,et al.  Mesoporous amorphous FePO4 nanospheres as high-performance cathode material for sodium-ion batteries. , 2014, Nano letters.

[2]  Sabihe Soleimanian-Zad,et al.  Fabrication of an electrochemical DNA-based biosensor for Bacillus cereus detection in milk and infant formula. , 2016, Biosensors & bioelectronics.

[3]  B. Logan,et al.  Graphite fiber brush anodes for increased power production in air-cathode microbial fuel cells. , 2007, Environmental science & technology.

[4]  Xin Wang,et al.  Concentration responses of toxicity sensor with Shewanella oneidensis MR-1 growing in bioelectrochemical systems. , 2013, Biosensors & bioelectronics.

[5]  Bing Li,et al.  Trace heavy metal ions promoted extracellular electron transfer and power generation by Shewanella in microbial fuel cells. , 2016, Bioresource technology.

[6]  Bruce E. Logan,et al.  Increased performance of single-chamber microbial fuel cells using an improved cathode structure , 2006 .

[7]  Xia Huang,et al.  Enhanced activated carbon cathode performance for microbial fuel cell by blending carbon black. , 2014, Environmental science & technology.

[8]  Lihua Zhu,et al.  Electrochemical sensor for levofloxacin based on molecularly imprinted polypyrrole–graphene–gold nanoparticles modified electrode , 2014 .

[9]  F. Wong,et al.  Rapid stereospecific high-performance liquid chromatographic determination of levofloxacin in human plasma and urine. , 1997, Journal of pharmaceutical and biomedical analysis.

[10]  Daliang Zhang,et al.  Design and synthesis of high performance LiFePO4/C nanomaterials for lithium ion batteries assisted by a facile H+/Li+ ion exchange reaction , 2015 .

[11]  Serge R. Guiot,et al.  Application of iron-based cathode catalysts in a microbial fuel cell , 2011 .

[12]  Bryan T Grenfell,et al.  Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data. , 2014, The Lancet. Infectious diseases.

[13]  J. Raoof,et al.  A novel self-powered and sensitive label-free DNA biosensor in microbial fuel cell. , 2016, Biosensors & bioelectronics.

[14]  Yong Yuan,et al.  Conversion of sewage sludge into high-performance bifunctional electrode materials for microbial energy harvesting , 2015 .

[15]  A. Kaur,et al.  Microbial fuel cell type biosensor for specific volatile fatty acids using acclimated bacterial communities. , 2013, Biosensors & bioelectronics.

[16]  N Sabaté,et al.  Silicon-based microfabricated microbial fuel cell toxicity sensor. , 2011, Biosensors & bioelectronics.

[17]  D. Lovley,et al.  Novel Mode of Microbial Energy Metabolism: Organic Carbon Oxidation Coupled to Dissimilatory Reduction of Iron or Manganese , 1988, Applied and environmental microbiology.

[18]  G. Ying,et al.  Comprehensive evaluation of antibiotics emission and fate in the river basins of China: source analysis, multimedia modeling, and linkage to bacterial resistance. , 2015, Environmental science & technology.

[19]  Peng Liang,et al.  Enhancing the response of microbial fuel cell based toxicity sensors to Cu(II) with the applying of flow-through electrodes and controlled anode potentials. , 2015, Bioresource technology.

[20]  Stefano Freguia,et al.  Microbial fuel cells: methodology and technology. , 2006, Environmental science & technology.

[21]  Yanyu Zhang,et al.  Partial degradation of levofloxacin for biodegradability improvement by electro-Fenton process using an activated carbon fiber felt cathode. , 2016, Journal of hazardous materials.

[22]  Irini Angelidaki,et al.  Microbial Electrochemical Systems and Technologies: It Is Time To Report the Capital Costs. , 2016, Environmental science & technology.

[23]  H. Ng,et al.  Polyaniline and iron based catalysts as air cathodes for enhanced oxygen reduction in microbial fuel cells , 2015 .

[24]  Keith Scott,et al.  A single-chamber microbial fuel cell as a biosensor for wastewaters. , 2009, Water research.

[25]  I Karube,et al.  Microbial electrode BOD sensors , 1977, Biotechnology and bioengineering.

[26]  Y. Yue,et al.  Biocarbon-coated LiFePO4 nucleus nanoparticles enhancing electrochemical performances. , 2012, Chemical communications.

[27]  Jimmy C. Yu,et al.  Enhanced photo-Fenton degradation of rhodamine B using graphene oxide-amorphous FePO₄ as effective and stable heterogeneous catalyst. , 2015, Journal of colloid and interface science.

[28]  K. Rajalakshmi,et al.  Vibrational analysis, electronic structure and nonlinear optical properties of levofloxacin by density functional theory. , 2013, Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.

[29]  S. K. Mehta,et al.  Photocatalytic degradation of the antibiotic levofloxacin using highly crystalline TiO2 nanoparticles , 2014 .

[30]  Zhisheng Lv,et al.  Ruthenium oxide-coated carbon felt electrode: A highly active anode for microbial fuel cell applications , 2012 .

[31]  Geoffrey M Gadd,et al.  A novel biomonitoring system using microbial fuel cells. , 2007, Journal of environmental monitoring : JEM.

[32]  A. Murugan,et al.  A rapid, one-pot microwave-solvothermal synthesis of a hierarchical nanostructured graphene/LiFePO4 hybrid as a high performance cathode for lithium ion batteries , 2013 .

[33]  Ioannis Ieropoulos,et al.  A small-scale air-cathode microbial fuel cell for on-line monitoring of water quality. , 2014, Biosensors & bioelectronics.

[34]  Hong Liu,et al.  Electricity generation using an air-cathode single chamber microbial fuel cell in the presence and absence of a proton exchange membrane. , 2004, Environmental science & technology.

[35]  Philippe Delahaut,et al.  Simultaneous determination of (fluoro)quinolone antibiotics in kidney, marine products, eggs, and muscle by enzyme-linked immunosorbent assay (ELISA). , 2006, Journal of agricultural and food chemistry.

[36]  Jianrong Chen,et al.  Facile synthesis of P-doped carbon quantum dots with highly efficient photoluminescence , 2014 .

[37]  L. Labiadh,et al.  Electrochemical mineralization of the antibiotic levofloxacin by electro-Fenton-pyrite process. , 2015, Chemosphere.

[38]  Zhidan Liu,et al.  Microbial fuel cell based biosensor for in situ monitoring of anaerobic digestion process. , 2011, Bioresource technology.

[39]  Jun Liu,et al.  Kinetic manipulation of the morphology evolution of FePO4 microcrystals: from rugbies to porous microspheres , 2009 .