Ensemble approach for differentiation of malignant melanoma

Melanoma is the deadliest type of skin cancer, yet it is the most treatable kind depending on its early diagnosis. The early prognosis of melanoma is a challenging task for both clinicians and dermatologists. Due to the importance of early diagnosis and in order to assist the dermatologists, we propose an automated framework based on ensemble learning methods and dermoscopy images to differentiate melanoma from dysplastic and benign lesions. The evaluation of our framework on the recent and public dermoscopy benchmark (PH2 dataset) indicates the potential of proposed method. Our evaluation, using only global features, revealed that ensembles such as random forest perform better than single learner. Using random forest ensemble and combination of color and texture features, our framework achieved the highest sensitivity of 94% and specificity of 92%.

[1]  Matti Pietikäinen,et al.  Multiresolution Gray-Scale and Rotation Invariant Texture Classification with Local Binary Patterns , 2002, IEEE Trans. Pattern Anal. Mach. Intell..

[2]  Robert M. Haralick,et al.  Textural Features for Image Classification , 1973, IEEE Trans. Syst. Man Cybern..

[3]  Jorge S. Marques,et al.  A Bag-of-Features Approach for the Classification of Melanomas in Dermoscopy Images: The Role of Color and Texture Descriptors , 2014 .

[4]  Rafael García,et al.  Computerized analysis of pigmented skin lesions: A review , 2012, Artif. Intell. Medicine.

[5]  Lior Rokach,et al.  Ensemble-based classifiers , 2010, Artificial Intelligence Review.

[6]  Pedro M. Ferreira,et al.  PH2 - A dermoscopic image database for research and benchmarking , 2013, 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[7]  Germán Capdehourat,et al.  Toward a combined tool to assist dermatologists in melanoma detection from dermoscopic images of pigmented skin lesions , 2011, Pattern Recognit. Lett..

[8]  Yoav Freund,et al.  Experiments with a New Boosting Algorithm , 1996, ICML.

[9]  Germán Capdehourat,et al.  Pigmented Skin Lesions Classification Using Dermatoscopic Images , 2009, CIARP.

[10]  B. S. Manjunath,et al.  Texture Features for Browsing and Retrieval of Image Data , 1996, IEEE Trans. Pattern Anal. Mach. Intell..

[11]  Lindsey A. Torre,et al.  Cancer Facts & Figures for Hispanics/Latinos 2012-2014 , 2009 .

[12]  Randy H. Moss,et al.  Detection of solid pigment in dermatoscopy images using texture analysis , 2000, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[13]  Leo Breiman,et al.  Bagging Predictors , 1996, Machine Learning.

[14]  Bill Triggs,et al.  Histograms of oriented gradients for human detection , 2005, 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05).

[15]  Ilias Maglogiannis,et al.  Overview of Advanced Computer Vision Systems for Skin Lesions Characterization , 2009, IEEE Transactions on Information Technology in Biomedicine.

[16]  G. Zouridakis,et al.  Malignant melanoma detection by Bag-of-Features classification , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[17]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[18]  Leen-Kiat Soh,et al.  Texture analysis of SAR sea ice imagery using gray level co-occurrence matrices , 1999, IEEE Trans. Geosci. Remote. Sens..

[19]  Jorge S. Marques,et al.  The Role of Keypoint Sampling on the Classification of Melanomas in Dermoscopy Images Using Bag-of-Features , 2013, IbPRIA.

[20]  David H. Wolpert,et al.  Stacked generalization , 1992, Neural Networks.

[21]  David A Clausi An analysis of co-occurrence texture statistics as a function of grey level quantization , 2002 .

[22]  V. del Marmol,et al.  Melanoma incidence and mortality in Europe: new estimates, persistent disparities , 2012, The British journal of dermatology.

[23]  Jorge S. Marques,et al.  What Is the Role of Color Symmetry in the Detection of Melanomas? , 2013, ISVC.

[24]  Randy H. Moss,et al.  A methodological approach to the classification of dermoscopy images , 2007, Comput. Medical Imaging Graph..

[25]  Vassilis P. Plagianakos,et al.  Skin Lesions Characterisation Utilising Clustering Algorithms , 2010, SETN.

[26]  Jorge S. Marques,et al.  On the role of shape in the detection of melanomas , 2013, 2013 8th International Symposium on Image and Signal Processing and Analysis (ISPA).

[27]  Ehsanollah Kabir,et al.  Improving the diagnostic accuracy of dysplastic and melanoma lesions using the decision template combination method , 2013, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[28]  Harald Ganster,et al.  Automated Melanoma Recognition , 2001, IEEE Trans. Medical Imaging.

[29]  Jorge S. Marques,et al.  Two Systems for the Detection of Melanomas in Dermoscopy Images Using Texture and Color Features , 2014, IEEE Systems Journal.

[30]  Lucila Ohno-Machado,et al.  A Comparison of Machine Learning Methods for the Diagnosis of Pigmented Skin Lesions , 2001, J. Biomed. Informatics.

[31]  Cordelia Schmid,et al.  Coloring Local Feature Extraction , 2006, ECCV.

[32]  Masafumi Hagiwara,et al.  An improved Internet-based melanoma screening system with dermatologist-like tumor area extraction algorithm , 2008, Comput. Medical Imaging Graph..

[33]  Zhenhua Guo,et al.  A Completed Modeling of Local Binary Pattern Operator for Texture Classification , 2010, IEEE Transactions on Image Processing.

[34]  Qaisar Abbas,et al.  Computer‐aided pattern classification system for dermoscopy images , 2012, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.