Actin-Myosin Force Generation and Symmetry Breaking in the Model Contractile Fiber

Myosin-powered force generation in nonmuscle cells underlies many cell biological processes and is based on contraction of random actin arrays. One of the most prominent examples of such arrays is ...

[1]  J. Meister,et al.  Cell shape dynamics reveal balance of elasticity and contractility in peripheral arcs. , 2015, Biophysical journal.

[2]  A. Carlsson,et al.  Mechanisms of cell propulsion by active stresses , 2011, New journal of physics.

[3]  Nir S. Gov,et al.  Sarcomeric Pattern Formation by Actin Cluster Coalescence , 2012, PLoS Comput. Biol..

[4]  Mark Bathe,et al.  The contractile ring coordinates curvature-dependent septum assembly during fission yeast cytokinesis , 2015, Molecular biology of the cell.

[5]  M. Gardel,et al.  F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex , 2012, Proceedings of the National Academy of Sciences.

[6]  G. Salbreux,et al.  Stresses at the Cell Surface during Animal Cell Morphogenesis , 2014, Current Biology.

[7]  M. Gardel,et al.  Thick filament length and isoform composition determine self-organized contractile units in actomyosin bundles. , 2013, Biophysical journal.

[8]  Pekka Lappalainen,et al.  Stress fibers are generated by two distinct actin assembly mechanisms in motile cells , 2006, The Journal of cell biology.

[9]  L S Kimpton,et al.  Multiple travelling-wave solutions in a minimal model for cell motility. , 2013, Mathematical medicine and biology : a journal of the IMA.

[10]  Michael W. Davidson,et al.  Nanoscale architecture of integrin-based cell adhesions , 2010, Nature.

[11]  Sean X. Sun,et al.  Active force generation in cross-linked filament bundles without motor proteins. , 2010, Physical review. E, Statistical, nonlinear, and soft matter physics.

[12]  B. O’Shaughnessy,et al.  Recoil after severing reveals stress fiber contraction mechanisms. , 2009, Biophysical journal.

[13]  Erin L. Barnhart,et al.  Balance between cell−substrate adhesion and myosin contraction determines the frequency of motility initiation in fish keratocytes , 2015, Proceedings of the National Academy of Sciences.

[14]  M. Gardel,et al.  Requirements for contractility in disordered cytoskeletal bundles , 2011, New journal of physics.

[15]  E. Stelzer,et al.  Viscoelastic response of contractile filament bundles. , 2011, Physical review. E, Statistical, nonlinear, and soft matter physics.

[16]  Patrick M. McCall,et al.  Self-organization of myosin II in reconstituted actomyosin bundles. , 2012, Biophysical journal.

[17]  Sam Walcott,et al.  Mechanical coupling between myosin molecules causes differences between ensemble and single-molecule measurements. , 2012, Biophysical journal.

[18]  Z. Kam,et al.  Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing , 2011, Nature Cell Biology.

[19]  Eric Mazur,et al.  Viscoelastic retraction of single living stress fibers and its impact on cell shape, cytoskeletal organization, and extracellular matrix mechanics. , 2006, Biophysical journal.

[20]  G. Genin,et al.  The role of mechanics in actin stress fiber kinetics. , 2013, Experimental cell research.

[21]  L. Truskinovsky,et al.  Contraction-driven cell motility. , 2013, Physical review letters.

[22]  J. Keener.  Principles Of Applied Mathematics: Transformation And Approximation , 2019 .

[23]  Dennis E Discher,et al.  Striated acto-myosin fibers can reorganize and register in response to elastic interactions with the matrix. , 2011, Biophysical journal.

[24]  T. Svitkina,et al.  Myosin II filament assemblies in the active lamella of fibroblasts: their morphogenesis and role in the formation of actin filament bundles , 1995, The Journal of cell biology.

[25]  Ken Jacobson,et al.  Actin-myosin viscoelastic flow in the keratocyte lamellipod. , 2009, Biophysical journal.

[26]  Sean X. Sun,et al.  Actin Crosslinkers: Repairing the Sense of Touch , 2010, Current Biology.

[27]  R. Krishnan,et al.  Generation of contractile actomyosin bundles depends on mechanosensitive actin filament assembly and disassembly , 2015, eLife.

[28]  Julie A. Theriot,et al.  An Adhesion-Dependent Switch between Mechanisms That Determine Motile Cell Shape , 2011, PLoS biology.

[29]  T. Svitkina,et al.  Self-sorting of nonmuscle myosins IIA and IIB polarizes the cytoskeleton and modulates cell motility , 2017, The Journal of cell biology.

[30]  Sean X. Sun,et al.  A mechanical model of actin stress fiber formation and substrate elasticity sensing in adherent cells , 2010, Proceedings of the National Academy of Sciences.

[31]  Pekka Lappalainen,et al.  Actin stress fibers – assembly, dynamics and biological roles , 2012, Journal of Cell Science.

[32]  M. Lord,et al.  Regulation of fission yeast myosin-II function and contractile ring dynamics by regulatory light-chain and heavy-chain phosphorylation. , 2009, Molecular biology of the cell.

[33]  Patrick W. Oakes,et al.  Dynamic and structural signatures of lamellar actomyosin force generation , 2011, Molecular biology of the cell.

[34]  Fred Chang,et al.  Actin dynamics in the contractile ring during cytokinesis in fission yeast , 2002, Nature.

[35]  M. Holmes.  Introduction to Perturbation Methods , 1995 .

[36]  F. Nédélec,et al.  Architecture and Connectivity Govern Actin Network Contractility , 2016, Current Biology.

[37]  T. Pollard.  Mechanics of cytokinesis in eukaryotes. , 2010, Current opinion in cell biology.

[38]  K. Burridge,et al.  The tension mounts: Stress fibers as force-generating mechanotransducers , 2013, The Journal of cell biology.

[39]  Tom Shemesh,et al.  Assembly and mechanosensory function of focal adhesions: experiments and models. , 2006, European journal of cell biology.

[40]  Frank Jülicher,et al.  Pattern formation in active fluids. , 2011, Physical review letters.

[41]  K. Fujiwara,et al.  Isolation and contraction of the stress fiber. , 1998, Molecular biology of the cell.

[42]  Keith Burridge,et al.  Simultaneous stretching and contraction of stress fibers in vivo. , 2004, Molecular biology of the cell.

[43]  D. Vavylonis,et al.  Formation of contractile networks and fibers in the medial cell cortex through myosin‐II turnover, contraction, and stress‐stabilization , 2015, Cytoskeleton.

[44]  John V. Small,et al.  Mechanosensing in actin stress fibers revealed by a close correlation between force and protein localization , 2009, Journal of Cell Science.

[45]  Gaudenz Danuser,et al.  Mathematical modeling of eukaryotic cell migration: insights beyond experiments. , 2013, Annual review of cell and developmental biology.

[46]  T. Pollard.  Nine unanswered questions about cytokinesis , 2017, The Journal of cell biology.

[47]  A. Mogilner,et al.  A Combination of Actin Treadmilling and Cross-Linking Drives Contraction of Random Actomyosin Arrays. , 2015, Biophysical journal.

[48]  Clare M Waterman,et al.  Mechanical integration of actin and adhesion dynamics in cell migration. , 2010, Annual review of cell and developmental biology.

[49]  Karen Oegema,et al.  Structural Memory in the Contractile Ring Makes the Duration of Cytokinesis Independent of Cell Size , 2009, Cell.

[50]  Sean X. Sun,et al.  Hysteresis in cross-bridge models of muscle. , 2009, Physical chemistry chemical physics : PCCP.

[51]  L. M. Chapin,et al.  A mechanical-biochemical feedback loop regulates remodeling in the actin cytoskeleton , 2014, Proceedings of the National Academy of Sciences.

[52]  Kenneth M. Yamada,et al.  Micro-environmental control of cell migration – myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics , 2012, Journal of Cell Science.

[53]  Margaret L. Gardel,et al.  Model-based Traction Force Microscopy Reveals Differential Tension in Cellular Actin Bundles , 2015, PLoS Comput. Biol..

[54]  P. Lappalainen,et al.  Mechanisms of actin stress fibre assembly , 2008, Journal of microscopy.