Albendazole Degradation Possibilities by UV-Based Advanced Oxidation Processes

Pharmaceuticals are present in an aquatic environment usually in low (ng/L) concentrations. Their continuous release can lead to unwanted effects on the nontarget organisms. The main points of their collection and release into the environment are wastewater treatment plants. The wastewater treatment plants should be upgraded by new technologies, like advanced oxidation processes (AOPs), to be able to degrade these new pollutants. In this study, the degradation of albendazole (ALB), a drug against parasitic helminths, was investigated using four UV-based AOPs: UV photolysis, UV photocatalysis (over TiO2 film), UV + O3, and UV + H2O2. The ranking of the degradation process degree of the ALB and its degradation products for studied processes is as follows: UV photolysis < UV photocatalysis with TiO2 < UV + O3 < UV + H2O2. The fastest degradation of ALB and its degradation products was obtained by UV-C + H2O2 process with a degradation efficiency of 99.95%, achieved in 15 minutes.

[1]  Davor Ljubas,et al.  Photocatalytic degradation of macrolide antibiotic azithromycin in aqueous sample , 2017 .

[2]  E. Bazrafshan,et al.  UV Activation of Persulfate for Removal of Penicillin G Antibiotics in Aqueous Solution , 2017, TheScientificWorldJournal.

[3]  Davor Ljubas,et al.  TiO2 assisted photocatalytic degradation of macrolide antibiotics , 2017 .

[4]  T. Vanek,et al.  Albendazole in environment: faecal concentrations in lambs and impact on lower development stages of helminths and seed germination , 2016, Environmental Science and Pollution Research.

[5]  Davor Ljubas,et al.  Photolytic and thin TiO2 film assisted photocatalytic degradation of sulfamethazine in aqueous solution , 2015, Environmental Science and Pollution Research.

[6]  Davor Ljubas,et al.  Photocatalytic degradation of Lissamine Green B dye by using nanostructured sol–gel TiO2 films , 2014 .

[7]  W. C. Li,et al.  Occurrence, sources, and fate of pharmaceuticals in aquatic environment and soil. , 2014, Environmental pollution.

[8]  Jung-Hwan Kwon,et al.  Evaluation of pharmaceuticals and personal care products with emphasis on anthelmintics in human sanitary waste, sewage, hospital wastewater, livestock wastewater and receiving water. , 2013, Journal of hazardous materials.

[9]  J. Marugán,et al.  Emerging micropollutant oxidation during disinfection processes using UV-C, UV-C/H2O2, UV-A/TiO2 and UV-A/TiO2/H2O2. , 2013, Water research.

[10]  V. Belgiorno,et al.  Degradation of Antibiotics in Wastewater during Sonolysis, Ozonation, and Their Simultaneous Application: Operating Conditions Effects and Processes Evaluation , 2012 .

[11]  A. Pintar,et al.  Ru/TiO2 catalyst for efficient removal of estrogens from aqueous samples by means of wet-air oxidation , 2012 .

[12]  Xin Yang,et al.  Occurrence and removal of pharmaceuticals and personal care products (PPCPs) in an advanced wastewater reclamation plant. , 2011, Water research.

[13]  Davor Ljubas,et al.  Synthesis, characterization and photocatalytic properties of sol-gel TiO2 films , 2011 .

[14]  A. M. Amat,et al.  Solar photocatalysis as a tertiary treatment to remove emerging pollutants from wastewater treatment plant effluents , 2011 .

[15]  W. Lambert,et al.  A field study on 8 pharmaceuticals and 1 pesticide in Belgium: removal rates in waste water treatment plants and occurrence in surface water. , 2010, The Science of the total environment.

[16]  G. Virkel,et al.  Enantiomeric behaviour of albendazole and fenbendazole sulfoxides in domestic animals: pharmacological implications. , 2009, Veterinary journal.

[17]  M. Gavrilescu,et al.  Pharmaceuticals, Personal Care Products and Endocrine Disrupting Agents in the Environment – A Review , 2009 .

[18]  D. Mantzavinos,et al.  Removal of residual pharmaceuticals from aqueous systems by advanced oxidation processes. , 2009, Environment international.

[19]  M. Gamal El-Din,et al.  Degradation of Aqueous Pharmaceuticals by Ozonation and Advanced Oxidation Processes: A Review , 2006 .

[20]  M. Petrovíc Analysis and removal of emerging contaminants in wastewater and drinking water , 2003 .

[21]  Gun-Young Park,et al.  Oxidation of pharmaceuticals during ozonation and advanced oxidation processes. , 2003, Environmental science & technology.

[22]  S. Jørgensen,et al.  Drugs in the environment. , 2000, Chemosphere.

[23]  M. Elovitz,et al.  Hydroxyl Radical/Ozone Ratios During Ozonation Processes. I. The Rct Concept , 1999 .

[24]  U. Gunten,et al.  Kinetics of the reaction between hydrogen peroxide and hypobromous acid: Implication on water treatment and natural systems , 1997 .

[25]  A. Hall,et al.  Albendazole as a treatment for infections with Giardia duodenalis in children in Bangladesh. , 1993, Transactions of the Royal Society of Tropical Medicine and Hygiene.

[26]  A. Jeffcoat,et al.  Aquatic photodegradation of albendazole and its major metabolites. 1. Photolysis rate and half-life for reactions in a tube , 1992 .

[27]  R. Wright,et al.  Aquatic photodegradation of albendazole and its major metabolites. 2. Reaction quantum yield, photolysis rate, and half-life in the environment , 1992 .

[28]  William H. Glaze,et al.  The Chemistry of Water Treatment Processes Involving Ozone, Hydrogen Peroxide and Ultraviolet Radiation , 1987 .